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Targeting KRAS mutations: orchestrating cancer evolution and therapeutic challenges.

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Title: Targeting KRAS mutations: orchestrating cancer evolution and therapeutic challenges.
Authors: Choucair K; Department of Oncology, Wayne State University School of Medicine, Detroit, MI, USA., Imtiaz H; Department of Oncology, Wayne State University School of Medicine, Detroit, MI, USA., Uddin MH; Department of Oncology, Wayne State University School of Medicine, Detroit, MI, USA., Nagasaka M; Department of Division of Hematology/Oncology and Medicine, School of Medicine University of California Irvine, Irvine, CA, USA., Al-Hallak MN; Department of Oncology, Wayne State University School of Medicine, Detroit, MI, USA., Philip PA; Henry Ford Health Systems, Detroit, MI, USA., El-Rayes B; Department of Internal Medicine, Department of Hematology and Oncology, University of Alabama at Birmingham, Birmingham, AL, USA., Pasche BC; Department of Oncology, Wayne State University School of Medicine, Detroit, MI, USA., Azmi AS; Department of Oncology, Wayne State University School of Medicine, Detroit, MI, USA. azmia@karmanos.org.
Source: Signal transduction and targeted therapy [Signal Transduct Target Ther] 2025 Nov 28; Vol. 10 (1), pp. 385. Date of Electronic Publication: 2025 Nov 28.
Publication Type: Journal Article; Review; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101676423 Publication Model: Electronic Cited Medium: Internet ISSN: 2059-3635 (Electronic) Linking ISSN: 20593635 NLM ISO Abbreviation: Signal Transduct Target Ther Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Targeting KRAS mutations: orchestrating cancer evolution and therapeutic challenges.
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  Data: <searchLink fieldCode="AU" term="%22Choucair+K%22">Choucair K</searchLink>; Department of Oncology, Wayne State University School of Medicine, Detroit, MI, USA.<br /><searchLink fieldCode="AU" term="%22Imtiaz+H%22">Imtiaz H</searchLink>; Department of Oncology, Wayne State University School of Medicine, Detroit, MI, USA.<br /><searchLink fieldCode="AU" term="%22Uddin+MH%22">Uddin MH</searchLink>; Department of Oncology, Wayne State University School of Medicine, Detroit, MI, USA.<br /><searchLink fieldCode="AU" term="%22Nagasaka+M%22">Nagasaka M</searchLink>; Department of Division of Hematology/Oncology and Medicine, School of Medicine University of California Irvine, Irvine, CA, USA.<br /><searchLink fieldCode="AU" term="%22Al-Hallak+MN%22">Al-Hallak MN</searchLink>; Department of Oncology, Wayne State University School of Medicine, Detroit, MI, USA.<br /><searchLink fieldCode="AU" term="%22Philip+PA%22">Philip PA</searchLink>; Henry Ford Health Systems, Detroit, MI, USA.<br /><searchLink fieldCode="AU" term="%22El-Rayes+B%22">El-Rayes B</searchLink>; Department of Internal Medicine, Department of Hematology and Oncology, University of Alabama at Birmingham, Birmingham, AL, USA.<br /><searchLink fieldCode="AU" term="%22Pasche+BC%22">Pasche BC</searchLink>; Department of Oncology, Wayne State University School of Medicine, Detroit, MI, USA.<br /><searchLink fieldCode="AU" term="%22Azmi+AS%22">Azmi AS</searchLink>; Department of Oncology, Wayne State University School of Medicine, Detroit, MI, USA. azmia@karmanos.org.
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        Value: 10.1038/s41392-025-02473-8
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              Text: 2025 Nov 28
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