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The CIP2A-TOPBP1 axis facilitates mitotic DNA repair via MiDAS and MMEJ.

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Title: The CIP2A-TOPBP1 axis facilitates mitotic DNA repair via MiDAS and MMEJ.
Authors: Martin PR; Division of Cell and Molecular Biology, The Institute of Cancer Research, London, UK. peter.martin@icr.ac.uk., Nieminuszczy J; Division of Cell and Molecular Biology, The Institute of Cancer Research, London, UK., Kozik Z; Division of Cell and Molecular Biology, The Institute of Cancer Research, London, UK., Jakub N; Division of Cell and Molecular Biology, The Institute of Cancer Research, London, UK., Kowalski S; Division of Cell and Molecular Biology, The Institute of Cancer Research, London, UK.; Department of Pharmacology, Faculty of Medicine, Medical University of Gdańsk, Gdańsk, Poland., Lecot M; Faculty of Medicine of Rennes, University of Rennes, Rennes, France., Vorhauser J; Division of Cell and Molecular Biology, The Institute of Cancer Research, London, UK., Lane KA; Division of Cell and Molecular Biology, The Institute of Cancer Research, London, UK., Kanellou A; Division of Cell and Molecular Biology, The Institute of Cancer Research, London, UK., Mansfeld J; Division of Cell and Molecular Biology, The Institute of Cancer Research, London, UK., Pearl LH; Division of Structural Biology, The Institute of Cancer Research, London, UK.; Genome Damage and Stability Centre, University of Sussex, Brighton, UK., Oliver AW; Genome Damage and Stability Centre, University of Sussex, Brighton, UK., Downs JA; Division of Cell and Molecular Biology, The Institute of Cancer Research, London, UK., Choudhary JS; Division of Cell and Molecular Biology, The Institute of Cancer Research, London, UK., Day M; Division of Structural Biology, The Institute of Cancer Research, London, UK.; Centre of Molecular Cell Biology, Queen Mary University of London, London, UK., Niedzwiedz W; Division of Cell and Molecular Biology, The Institute of Cancer Research, London, UK. wojciech.niedzwiedz@icr.ac.uk.
Source: Nature communications [Nat Commun] 2025 Nov 27; Vol. 16 (1), pp. 10623. Date of Electronic Publication: 2025 Nov 27.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22Martin+PR%22">Martin PR</searchLink>; Division of Cell and Molecular Biology, The Institute of Cancer Research, London, UK. peter.martin@icr.ac.uk.<br /><searchLink fieldCode="AU" term="%22Nieminuszczy+J%22">Nieminuszczy J</searchLink>; Division of Cell and Molecular Biology, The Institute of Cancer Research, London, UK.<br /><searchLink fieldCode="AU" term="%22Kozik+Z%22">Kozik Z</searchLink>; Division of Cell and Molecular Biology, The Institute of Cancer Research, London, UK.<br /><searchLink fieldCode="AU" term="%22Jakub+N%22">Jakub N</searchLink>; Division of Cell and Molecular Biology, The Institute of Cancer Research, London, UK.<br /><searchLink fieldCode="AU" term="%22Kowalski+S%22">Kowalski S</searchLink>; Division of Cell and Molecular Biology, The Institute of Cancer Research, London, UK.; Department of Pharmacology, Faculty of Medicine, Medical University of Gdańsk, Gdańsk, Poland.<br /><searchLink fieldCode="AU" term="%22Lecot+M%22">Lecot M</searchLink>; Faculty of Medicine of Rennes, University of Rennes, Rennes, France.<br /><searchLink fieldCode="AU" term="%22Vorhauser+J%22">Vorhauser J</searchLink>; Division of Cell and Molecular Biology, The Institute of Cancer Research, London, UK.<br /><searchLink fieldCode="AU" term="%22Lane+KA%22">Lane KA</searchLink>; Division of Cell and Molecular Biology, The Institute of Cancer Research, London, UK.<br /><searchLink fieldCode="AU" term="%22Kanellou+A%22">Kanellou A</searchLink>; Division of Cell and Molecular Biology, The Institute of Cancer Research, London, UK.<br /><searchLink fieldCode="AU" term="%22Mansfeld+J%22">Mansfeld J</searchLink>; Division of Cell and Molecular Biology, The Institute of Cancer Research, London, UK.<br /><searchLink fieldCode="AU" term="%22Pearl+LH%22">Pearl LH</searchLink>; Division of Structural Biology, The Institute of Cancer Research, London, UK.; Genome Damage and Stability Centre, University of Sussex, Brighton, UK.<br /><searchLink fieldCode="AU" term="%22Oliver+AW%22">Oliver AW</searchLink>; Genome Damage and Stability Centre, University of Sussex, Brighton, UK.<br /><searchLink fieldCode="AU" term="%22Downs+JA%22">Downs JA</searchLink>; Division of Cell and Molecular Biology, The Institute of Cancer Research, London, UK.<br /><searchLink fieldCode="AU" term="%22Choudhary+JS%22">Choudhary JS</searchLink>; Division of Cell and Molecular Biology, The Institute of Cancer Research, London, UK.<br /><searchLink fieldCode="AU" term="%22Day+M%22">Day M</searchLink>; Division of Structural Biology, The Institute of Cancer Research, London, UK.; Centre of Molecular Cell Biology, Queen Mary University of London, London, UK.<br /><searchLink fieldCode="AU" term="%22Niedzwiedz+W%22">Niedzwiedz W</searchLink>; Division of Cell and Molecular Biology, The Institute of Cancer Research, London, UK. wojciech.niedzwiedz@icr.ac.uk.
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