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Reduced Cas9 transgene silencing by incorporation of intron sequences.

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Title: Reduced Cas9 transgene silencing by incorporation of intron sequences.
Authors: Arana S; Department of Genetics, School of Medicine, Stanford University, Stanford, CA, USA.; Department of Neurosurgery, School of Medicine, Stanford University, Stanford, CA, USA., Du PP; Department of Genetics, School of Medicine, Stanford University, Stanford, CA, USA.; Cancer Biology Program, School of Medicine, Stanford University, Stanford, CA, USA., Vaughan-Jackson A; Department of Genetics, School of Medicine, Stanford University, Stanford, CA, USA.; Chan Zuckerberg Biohub, San Francisco, CA, USA., Enright N; Department of Genetics, School of Medicine, Stanford University, Stanford, CA, USA., Spees K; Department of Genetics, School of Medicine, Stanford University, Stanford, CA, USA., Valbuena R; Department of Genetics, School of Medicine, Stanford University, Stanford, CA, USA., Garcia CA; Department of Genetics, School of Medicine, Stanford University, Stanford, CA, USA., Nguyen T; Division of Pediatric Hematology/Oncology, Lucile Packard Children's Hospital, Stanford, CA, USA., Venida A; Department of Genetics, School of Medicine, Stanford University, Stanford, CA, USA., Seczynska M; Department of Genetics, School of Medicine, Stanford University, Stanford, CA, USA., Bintu L; Department of Bioengineering, Stanford University, Stanford, CA, USA., Lehner PJ; Cambridge Institute for Therapeutic Immunology and Infectious Disease, Jeffrey Cheah Biomedical Centre, Cambridge Biomedical Campus, University of Cambridge, Cambridge, UK., Prolo LM; Department of Neurosurgery, School of Medicine, Stanford University, Stanford, CA, USA., Bassik MC; Department of Genetics, School of Medicine, Stanford University, Stanford, CA, USA. bassik@stanford.edu.
Source: Nature communications [Nat Commun] 2025 Nov 27; Vol. 16 (1), pp. 10656. Date of Electronic Publication: 2025 Nov 27.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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