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Space radiation induces distinct senescent phenotypes: Implications for space travel.

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Title: Space radiation induces distinct senescent phenotypes: Implications for space travel.
Authors: Pitcher LE; Masonic Institute on the Biology of Aging and Metabolism and Department of Biochemistry, Molecular Biology and Biophysics, University of Minnesota, Minneapolis, MN, USA., Mukherjee B; Department of Neurosurgery, University of Texas Health Science Center, San Antonio, TX, USA., Saathoff AM; Masonic Institute on the Biology of Aging and Metabolism and Department of Biochemistry, Molecular Biology and Biophysics, University of Minnesota, Minneapolis, MN, USA., Eduvas ZA; Masonic Institute on the Biology of Aging and Metabolism and Department of Biochemistry, Molecular Biology and Biophysics, University of Minnesota, Minneapolis, MN, USA., Bartz J; Masonic Institute on the Biology of Aging and Metabolism, University of Minnesota and Department of Genetics, Cell Biology, and Development, 420 Washington Avenue SE, Minneapolis, MN, USA., Zhang X; Robert and Arlene Kogod Center on Aging, Mayo Clinic, Rochester, MN, USA., Giorgadze N; Center for Advanced Gerotherapeutics, Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, CA, USA., Pirtskhalava T; Center for Advanced Gerotherapeutics, Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, CA, USA., Habib AA; Department of Neurology, University of Texas Southwestern Medical Center, Dallas, TX, USA., LeBrasseur NK; Robert and Arlene Kogod Center on Aging, Mayo Clinic, Rochester, MN, USA., Tchkonia T; Center for Advanced Gerotherapeutics, Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, CA, USA., Kirkland JL; Center for Advanced Gerotherapeutics, Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, CA, USA., Dong X; Masonic Institute on the Biology of Aging and Metabolism, University of Minnesota and Department of Genetics, Cell Biology, and Development, 420 Washington Avenue SE, Minneapolis, MN, USA., Burma S; Department of Neurosurgery, University of Texas Health Science Center, San Antonio, TX, USA. burma@uthscsa.edu., Robbins PD; Masonic Institute on the Biology of Aging and Metabolism and Department of Biochemistry, Molecular Biology and Biophysics, University of Minnesota, Minneapolis, MN, USA. probbins@umn.edu.
Source: Npj aging [NPJ Aging] 2025 Nov 27; Vol. 11 (1), pp. 95. Date of Electronic Publication: 2025 Nov 27.
Publication Type: Journal Article
Journal Info: Publisher: Springer Nature Country of Publication: England NLM ID: 9918402285106676 Publication Model: Electronic Cited Medium: Internet ISSN: 2731-6068 (Electronic) Linking ISSN: 27316068 NLM ISO Abbreviation: NPJ Aging Subsets: PubMed not MEDLINE
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  Data: Space radiation induces distinct senescent phenotypes: Implications for space travel.
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  Data: <searchLink fieldCode="AU" term="%22Pitcher+LE%22">Pitcher LE</searchLink>; Masonic Institute on the Biology of Aging and Metabolism and Department of Biochemistry, Molecular Biology and Biophysics, University of Minnesota, Minneapolis, MN, USA.<br /><searchLink fieldCode="AU" term="%22Mukherjee+B%22">Mukherjee B</searchLink>; Department of Neurosurgery, University of Texas Health Science Center, San Antonio, TX, USA.<br /><searchLink fieldCode="AU" term="%22Saathoff+AM%22">Saathoff AM</searchLink>; Masonic Institute on the Biology of Aging and Metabolism and Department of Biochemistry, Molecular Biology and Biophysics, University of Minnesota, Minneapolis, MN, USA.<br /><searchLink fieldCode="AU" term="%22Eduvas+ZA%22">Eduvas ZA</searchLink>; Masonic Institute on the Biology of Aging and Metabolism and Department of Biochemistry, Molecular Biology and Biophysics, University of Minnesota, Minneapolis, MN, USA.<br /><searchLink fieldCode="AU" term="%22Bartz+J%22">Bartz J</searchLink>; Masonic Institute on the Biology of Aging and Metabolism, University of Minnesota and Department of Genetics, Cell Biology, and Development, 420 Washington Avenue SE, Minneapolis, MN, USA.<br /><searchLink fieldCode="AU" term="%22Zhang+X%22">Zhang X</searchLink>; Robert and Arlene Kogod Center on Aging, Mayo Clinic, Rochester, MN, USA.<br /><searchLink fieldCode="AU" term="%22Giorgadze+N%22">Giorgadze N</searchLink>; Center for Advanced Gerotherapeutics, Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, CA, USA.<br /><searchLink fieldCode="AU" term="%22Pirtskhalava+T%22">Pirtskhalava T</searchLink>; Center for Advanced Gerotherapeutics, Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, CA, USA.<br /><searchLink fieldCode="AU" term="%22Habib+AA%22">Habib AA</searchLink>; Department of Neurology, University of Texas Southwestern Medical Center, Dallas, TX, USA.<br /><searchLink fieldCode="AU" term="%22LeBrasseur+NK%22">LeBrasseur NK</searchLink>; Robert and Arlene Kogod Center on Aging, Mayo Clinic, Rochester, MN, USA.<br /><searchLink fieldCode="AU" term="%22Tchkonia+T%22">Tchkonia T</searchLink>; Center for Advanced Gerotherapeutics, Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, CA, USA.<br /><searchLink fieldCode="AU" term="%22Kirkland+JL%22">Kirkland JL</searchLink>; Center for Advanced Gerotherapeutics, Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, CA, USA.<br /><searchLink fieldCode="AU" term="%22Dong+X%22">Dong X</searchLink>; Masonic Institute on the Biology of Aging and Metabolism, University of Minnesota and Department of Genetics, Cell Biology, and Development, 420 Washington Avenue SE, Minneapolis, MN, USA.<br /><searchLink fieldCode="AU" term="%22Burma+S%22">Burma S</searchLink>; Department of Neurosurgery, University of Texas Health Science Center, San Antonio, TX, USA. burma@uthscsa.edu.<br /><searchLink fieldCode="AU" term="%22Robbins+PD%22">Robbins PD</searchLink>; Masonic Institute on the Biology of Aging and Metabolism and Department of Biochemistry, Molecular Biology and Biophysics, University of Minnesota, Minneapolis, MN, USA. probbins@umn.edu.
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