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Human plasma proteomic profile of clonal hematopoiesis.

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Title: Human plasma proteomic profile of clonal hematopoiesis.
Authors: Yu Z; Clinical and Translational Epidemiology Unit, Massachusetts General Hospital, Boston, MA, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Cardiovascular Research Center and Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA., Vromman A; Division of Cardiovascular Medicine, Brigham and Women's Hospital Heart & Vascular Center, Boston, MA, USA., Nguyen NQH; Department of Epidemiology, Human Genetics and Environmental Sciences, School of Public Health, University of Texas Health Science Center at Houston, Houston, TX, USA., Schuermans A; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Cardiovascular Research Center and Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA.; Faculty of Medicine, KU Leuven, Leuven, Belgium., Li L; Clinical and Translational Epidemiology Unit, Massachusetts General Hospital, Boston, MA, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Rentz T; Division of Cardiovascular Medicine, Brigham and Women's Hospital Heart & Vascular Center, Boston, MA, USA., Nakao T; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Cardiovascular Research Center and Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA.; Division of Cardiovascular Medicine, Brigham and Women's Hospital Heart & Vascular Center, Boston, MA, USA., Vellarikkal SK; Division of Cardiovascular Medicine, Brigham and Women's Hospital Heart & Vascular Center, Boston, MA, USA., Uddin MM; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Cardiovascular Research Center and Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA., Niroula A; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Medical Biochemistry and Cell Biology, Institute of Biomedicine, University of Gothenburg, Gothenburg, Sweden.; SciLifeLab, University of Gothenburg, Gothenburg, Sweden., Griffin G; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Pathology, Brigham and Women's Hospital, Boston, MA, USA.; Department of Pathology, Dana-Farber Cancer Institute, Boston, MA, USA., Honigberg MC; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Cardiovascular Research Center and Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA.; Department of Medicine, Harvard Medical School, Boston, MA, USA., Lin AE; Division of Cardiology, Section of Cardio-Oncology and Immunology, University of California-San Francisco, San Francisco, CA, USA., Gibson CJ; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA., Katz DH; Division of Cardiovascular Medicine, Beth Israel Deaconess Medical Center, Boston, MA, USA.; Department of Cardiovascular Medicine, Stanford University, Stanford, CA, USA., Tahir UA; Division of Cardiovascular Medicine, Beth Israel Deaconess Medical Center, Boston, MA, USA., Fang S; Department of Epidemiology, Human Genetics and Environmental Sciences, School of Public Health, University of Texas Health Science Center at Houston, Houston, TX, USA., Dron JS; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Cardiovascular Research Center and Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA., Pan M; Cardiovascular Research Center and Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA.; Department of Medicine, Harvard Medical School, Boston, MA, USA., Haidermota S; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Cardiovascular Research Center and Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA., Ganesh S; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Cardiovascular Research Center and Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA., Antoine T; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Cardiovascular Research Center and Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA., Weinstock J; Department of Human Genetics, Emory University School of Medicine, Atlanta, GA, USA., Austin TR; Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, WA, USA.; Department of Epidemiology, University of Washington, Seattle, WA, USA., Vasan RS; University of Texas Health Sciences Center, San Antonio, TX, USA.; Framingham Heart Study, Framingham, MA, USA., Peloso GM; Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA., Hornsby W; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Cardiovascular Research Center and Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA., Ganz P; Division of Cardiology, Zuckerberg San Francisco General Hospital and Department of Medicine, University of California, San Francisco, CA, USA., Manson JE; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, USA.; Division of Preventive Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA., Haring B; Department of Medicine IV, Clinic Hietzing, Vienna, Austria., Kooperberg C; Public Health Sciences Division, Fred Hutchinson Cancer Center, Seattle, WA, USA., Reiner AP; Public Health Sciences Division, Fred Hutchinson Cancer Center, Seattle, WA, USA.; Department of Health Systems and Population Health, University of Washington, Seattle, WA, USA., Bis JC; Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, WA, USA., Psaty BM; Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, WA, USA.; Department of Epidemiology, University of Washington, Seattle, WA, USA.; Department of Health Systems and Population Health, University of Washington, Seattle, WA, USA., Min YI; Department of Medicine, University of Mississippi Medical Center, Jackson, MS, USA., Correa A; Department of Medicine, University of Mississippi Medical Center, Jackson, MS, USA., Lange LA; Department of Medicine, Division of Biomedical Informatics and Personalized Medicine, University of Colorado Anschutz Medical Campus, Denver, CO, USA., Post WS; Division of Cardiology, Department of Medicine, Johns Hopkins University, Baltimore, MD, USA., Rotter JI; The Institute for Translational Genomics and Population Sciences, Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA, USA., Rich SS; Department of Genome Sciences, University of Virginia, Charlottesville, VA, USA., Wilson JG; Division of Cardiovascular Medicine, Beth Israel Deaconess Medical Center, Boston, MA, USA., Ebert BL; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Medicine, Harvard Medical School, Boston, MA, USA.; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA., Yu B; Department of Epidemiology, Human Genetics and Environmental Sciences, School of Public Health, University of Texas Health Science Center at Houston, Houston, TX, USA., Ballantyne CM; Department of Medicine, Baylor College of Medicine, Houston, TX, USA., Coresh J; Departments of Population Health and Medicine, NYU Grossman School of Medicine, New York, NY, USA., Sankaran VG; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Division of Hematology and Oncology, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA.; Harvard Stem Cell Institute, Cambridge, MA, USA.; Howard Hughes Medical Institute, Boston, MA, USA., Bick AG; Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA., Jaiswal S; Department of Pathology and Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, CA, USA., Gerszten RE; Department of Medicine, Harvard Medical School, Boston, MA, USA.; Division of Cardiovascular Medicine, Beth Israel Deaconess Medical Center, Boston, MA, USA., Libby P; Division of Cardiovascular Medicine, Brigham and Women's Hospital Heart & Vascular Center, Boston, MA, USA., Gupta RM; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Division of Cardiovascular Medicine, Brigham and Women's Hospital Heart & Vascular Center, Boston, MA, USA., Natarajan P; Broad Institute of MIT and Harvard, Cambridge, MA, USA. pnatarajan@mgh.harvard.edu.; Cardiovascular Research Center and Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA. pnatarajan@mgh.harvard.edu.; Department of Medicine, Harvard Medical School, Boston, MA, USA. pnatarajan@mgh.harvard.edu.
Corporate Authors: NHLBI Trans-Omics for Precision Medicine
Source: Nature communications [Nat Commun] 2025 Nov 27; Vol. 16 (1), pp. 11688. Date of Electronic Publication: 2025 Nov 27.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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            NameFull: Ballantyne CM
      – PersonEntity:
          Name:
            NameFull: Coresh J
      – PersonEntity:
          Name:
            NameFull: Sankaran VG
      – PersonEntity:
          Name:
            NameFull: Bick AG
      – PersonEntity:
          Name:
            NameFull: Jaiswal S
      – PersonEntity:
          Name:
            NameFull: Gerszten RE
      – PersonEntity:
          Name:
            NameFull: Libby P
      – PersonEntity:
          Name:
            NameFull: Gupta RM
      – PersonEntity:
          Name:
            NameFull: Natarajan P
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 27
              M: 11
              Text: 2025 Nov 27
              Type: published
              Y: 2025
          Identifiers:
            – Type: issn-electronic
              Value: 2041-1723
          Numbering:
            – Type: volume
              Value: 16
            – Type: issue
              Value: 1
          Titles:
            – TitleFull: Nature communications
              Type: main
ResultId 1