12/15-lipoxygenase deficiency attenuates disturbed flow-induced LDL oxidation in endothelial cells.

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Title: 12/15-lipoxygenase deficiency attenuates disturbed flow-induced LDL oxidation in endothelial cells.
Authors: Chen JW; Department of Cardiovascular Medicine, Ruijin Hospital, Shanghai Jiao-Tong University School of Medicine, Shanghai, 200025, China; Institute of Cardiovascular Diseases, Shanghai Jiao-Tong University School of Medicine, Shanghai, 200025, China., Li YR; Department of Cardiovascular Medicine, Ruijin Hospital, Shanghai Jiao-Tong University School of Medicine, Shanghai, 200025, China; Institute of Cardiovascular Diseases, Shanghai Jiao-Tong University School of Medicine, Shanghai, 200025, China., Tao LY; Department of Cardiovascular Medicine, Ruijin Hospital, Shanghai Jiao-Tong University School of Medicine, Shanghai, 200025, China; Institute of Cardiovascular Diseases, Shanghai Jiao-Tong University School of Medicine, Shanghai, 200025, China., Tang SY; Department of Cardiovascular Medicine, Ruijin Hospital, Shanghai Jiao-Tong University School of Medicine, Shanghai, 200025, China; Institute of Cardiovascular Diseases, Shanghai Jiao-Tong University School of Medicine, Shanghai, 200025, China., Shu XY; Department of Cardiovascular Medicine, Ruijin Hospital, Shanghai Jiao-Tong University School of Medicine, Shanghai, 200025, China; Institute of Cardiovascular Diseases, Shanghai Jiao-Tong University School of Medicine, Shanghai, 200025, China., Feng S; Department of Cardiovascular Medicine, Ruijin Hospital, Shanghai Jiao-Tong University School of Medicine, Shanghai, 200025, China., Yuan RS; Department of Cardiovascular Medicine, Ruijin Hospital, Shanghai Jiao-Tong University School of Medicine, Shanghai, 200025, China., Tay GP; Department of Cardiovascular Medicine, Ruijin Hospital, Shanghai Jiao-Tong University School of Medicine, Shanghai, 200025, China; Institute of Cardiovascular Diseases, Shanghai Jiao-Tong University School of Medicine, Shanghai, 200025, China., Zhang RY; Department of Cardiovascular Medicine, Ruijin Hospital, Shanghai Jiao-Tong University School of Medicine, Shanghai, 200025, China; Institute of Cardiovascular Diseases, Shanghai Jiao-Tong University School of Medicine, Shanghai, 200025, China., Yang CD; Department of Cardiovascular Medicine, Ruijin Hospital, Shanghai Jiao-Tong University School of Medicine, Shanghai, 200025, China. Electronic address: yangcd@shsmu.edu.cn., Wang XQ; Department of Cardiovascular Medicine, Ruijin Hospital, Shanghai Jiao-Tong University School of Medicine, Shanghai, 200025, China; Institute of Cardiovascular Diseases, Shanghai Jiao-Tong University School of Medicine, Shanghai, 200025, China. Electronic address: wangxq@shsmu.edu.cn.
Source: Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2026 Jan 01; Vol. 794, pp. 153010. Date of Electronic Publication: 2025 Nov 19.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 0372516 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1090-2104 (Electronic) Linking ISSN: 0006291X NLM ISO Abbreviation: Biochem Biophys Res Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: 12/15-lipoxygenase deficiency attenuates disturbed flow-induced LDL oxidation in endothelial cells.
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  Data: <searchLink fieldCode="AU" term="%22Chen+JW%22">Chen JW</searchLink>; Department of Cardiovascular Medicine, Ruijin Hospital, Shanghai Jiao-Tong University School of Medicine, Shanghai, 200025, China; Institute of Cardiovascular Diseases, Shanghai Jiao-Tong University School of Medicine, Shanghai, 200025, China.<br /><searchLink fieldCode="AU" term="%22Li+YR%22">Li YR</searchLink>; Department of Cardiovascular Medicine, Ruijin Hospital, Shanghai Jiao-Tong University School of Medicine, Shanghai, 200025, China; Institute of Cardiovascular Diseases, Shanghai Jiao-Tong University School of Medicine, Shanghai, 200025, China.<br /><searchLink fieldCode="AU" term="%22Tao+LY%22">Tao LY</searchLink>; Department of Cardiovascular Medicine, Ruijin Hospital, Shanghai Jiao-Tong University School of Medicine, Shanghai, 200025, China; Institute of Cardiovascular Diseases, Shanghai Jiao-Tong University School of Medicine, Shanghai, 200025, China.<br /><searchLink fieldCode="AU" term="%22Tang+SY%22">Tang SY</searchLink>; Department of Cardiovascular Medicine, Ruijin Hospital, Shanghai Jiao-Tong University School of Medicine, Shanghai, 200025, China; Institute of Cardiovascular Diseases, Shanghai Jiao-Tong University School of Medicine, Shanghai, 200025, China.<br /><searchLink fieldCode="AU" term="%22Shu+XY%22">Shu XY</searchLink>; Department of Cardiovascular Medicine, Ruijin Hospital, Shanghai Jiao-Tong University School of Medicine, Shanghai, 200025, China; Institute of Cardiovascular Diseases, Shanghai Jiao-Tong University School of Medicine, Shanghai, 200025, China.<br /><searchLink fieldCode="AU" term="%22Feng+S%22">Feng S</searchLink>; Department of Cardiovascular Medicine, Ruijin Hospital, Shanghai Jiao-Tong University School of Medicine, Shanghai, 200025, China.<br /><searchLink fieldCode="AU" term="%22Yuan+RS%22">Yuan RS</searchLink>; Department of Cardiovascular Medicine, Ruijin Hospital, Shanghai Jiao-Tong University School of Medicine, Shanghai, 200025, China.<br /><searchLink fieldCode="AU" term="%22Tay+GP%22">Tay GP</searchLink>; Department of Cardiovascular Medicine, Ruijin Hospital, Shanghai Jiao-Tong University School of Medicine, Shanghai, 200025, China; Institute of Cardiovascular Diseases, Shanghai Jiao-Tong University School of Medicine, Shanghai, 200025, China.<br /><searchLink fieldCode="AU" term="%22Zhang+RY%22">Zhang RY</searchLink>; Department of Cardiovascular Medicine, Ruijin Hospital, Shanghai Jiao-Tong University School of Medicine, Shanghai, 200025, China; Institute of Cardiovascular Diseases, Shanghai Jiao-Tong University School of Medicine, Shanghai, 200025, China.<br /><searchLink fieldCode="AU" term="%22Yang+CD%22">Yang CD</searchLink>; Department of Cardiovascular Medicine, Ruijin Hospital, Shanghai Jiao-Tong University School of Medicine, Shanghai, 200025, China. Electronic address: yangcd@shsmu.edu.cn.<br /><searchLink fieldCode="AU" term="%22Wang+XQ%22">Wang XQ</searchLink>; Department of Cardiovascular Medicine, Ruijin Hospital, Shanghai Jiao-Tong University School of Medicine, Shanghai, 200025, China; Institute of Cardiovascular Diseases, Shanghai Jiao-Tong University School of Medicine, Shanghai, 200025, China. Electronic address: wangxq@shsmu.edu.cn.
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  Data: <searchLink fieldCode="JN" term="%220372516%22">Biochemical and biophysical research communications</searchLink> [Biochem Biophys Res Commun] 2026 Jan 01; Vol. 794, pp. 153010. <i>Date of Electronic Publication: </i>2025 Nov 19.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier%22">Elsevier </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>0372516 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1090-2104 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%220006291X%22">0006291X </searchLink><i>NLM ISO Abbreviation: </i>Biochem Biophys Res Commun <i>Subsets: </i>MEDLINE
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        Value: 10.1016/j.bbrc.2025.153010
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      – TitleFull: 12/15-lipoxygenase deficiency attenuates disturbed flow-induced LDL oxidation in endothelial cells.
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              M: 01
              Text: 2026 Jan 01
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