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Synergistic antiviral activity against human adenovirus through combination of itraconazole and brincidofovir.

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Title: Synergistic antiviral activity against human adenovirus through combination of itraconazole and brincidofovir.
Authors: Zamzamy M; Research Department Virus Immunology, Leibniz Institute of Virology, Hamburg, Germany., Post S; Research Department Virus Immunology, Leibniz Institute of Virology, Hamburg, Germany., Ip WH; Research Department Viral Transformation, Leibniz Institute of Virology, Hamburg, Germany., Hahlin E; Research Department of Clinical Microbiology, Umeå University, Umeå, Sweden.; Umeå Centre for Microbial Research (UCMR), Umeå University, Umeå, Sweden.; Molecular Infection Biology Sweden (MIMS), Umeå University, Umeå, Sweden.; Science for Life Laboratory (SciLifeLab), Umeå University, Umeå, Sweden., Kühn S; Technology Platform Microscopy and Image Analysis, Leibniz Institute of Virology, Hamburg, Germany., Pirosu A; Research Department Virus Immunology, Leibniz Institute of Virology, Hamburg, Germany., Conze C; Technology Platform Microscopy and Image Analysis, Leibniz Institute of Virology, Hamburg, Germany., Baumdick M; Research Department Virus Immunology, Leibniz Institute of Virology, Hamburg, Germany.; Division for Regenerative Medicine and Immunology, III. Department of Medicine, University Medical Center Hamburg-Eppendorf (UKE), Hamburg, Germany., Bunders MJ; Research Department Virus Immunology, Leibniz Institute of Virology, Hamburg, Germany.; Division for Regenerative Medicine and Immunology, III. Department of Medicine, University Medical Center Hamburg-Eppendorf (UKE), Hamburg, Germany., Zecher BF; Research Department Virus Immunology, Leibniz Institute of Virology, Hamburg, Germany.; I. Department of Medicine, University Medical Centre Hamburg-Eppendorf, Hamburg, Germany., Hoelzemer A; I. Department of Medicine, University Medical Centre Hamburg-Eppendorf, Hamburg, Germany.; Institute for Infection Research and Vaccine Development (IIRVD), University Medical Centre Hamburg-Eppendorf, Hamburg, Germany., Linder S; Institute for Medical Microbiology, Virology and Hygiene, University Medical Centre Hamburg-Eppendorf, Hamburg, Germany., Arnberg N; Research Department of Clinical Microbiology, Umeå University, Umeå, Sweden.; Umeå Centre for Microbial Research (UCMR), Umeå University, Umeå, Sweden.; Molecular Infection Biology Sweden (MIMS), Umeå University, Umeå, Sweden.; Science for Life Laboratory (SciLifeLab), Umeå University, Umeå, Sweden., Dobner T; Research Department Viral Transformation, Leibniz Institute of Virology, Hamburg, Germany., Altfeld M; Research Department Virus Immunology, Leibniz Institute of Virology, Hamburg, Germany., Schloer S; Research Department Virus Immunology, Leibniz Institute of Virology, Hamburg, Germany.; Institute of Immunology, University Medical Centre Hamburg-Eppendorf, Hamburg, Germany.
Source: British journal of pharmacology [Br J Pharmacol] 2026 Apr; Vol. 183 (7), pp. 1578-1601. Date of Electronic Publication: 2025 Nov 28.
Publication Type: Journal Article
Journal Info: Publisher: Wiley Country of Publication: England NLM ID: 7502536 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5381 (Electronic) Linking ISSN: 00071188 NLM ISO Abbreviation: Br J Pharmacol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Zamzamy+M%22">Zamzamy M</searchLink>; Research Department Virus Immunology, Leibniz Institute of Virology, Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Post+S%22">Post S</searchLink>; Research Department Virus Immunology, Leibniz Institute of Virology, Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Ip+WH%22">Ip WH</searchLink>; Research Department Viral Transformation, Leibniz Institute of Virology, Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Hahlin+E%22">Hahlin E</searchLink>; Research Department of Clinical Microbiology, Umeå University, Umeå, Sweden.; Umeå Centre for Microbial Research (UCMR), Umeå University, Umeå, Sweden.; Molecular Infection Biology Sweden (MIMS), Umeå University, Umeå, Sweden.; Science for Life Laboratory (SciLifeLab), Umeå University, Umeå, Sweden.<br /><searchLink fieldCode="AU" term="%22Kühn+S%22">Kühn S</searchLink>; Technology Platform Microscopy and Image Analysis, Leibniz Institute of Virology, Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Pirosu+A%22">Pirosu A</searchLink>; Research Department Virus Immunology, Leibniz Institute of Virology, Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Conze+C%22">Conze C</searchLink>; Technology Platform Microscopy and Image Analysis, Leibniz Institute of Virology, Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Baumdick+M%22">Baumdick M</searchLink>; Research Department Virus Immunology, Leibniz Institute of Virology, Hamburg, Germany.; Division for Regenerative Medicine and Immunology, III. Department of Medicine, University Medical Center Hamburg-Eppendorf (UKE), Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Bunders+MJ%22">Bunders MJ</searchLink>; Research Department Virus Immunology, Leibniz Institute of Virology, Hamburg, Germany.; Division for Regenerative Medicine and Immunology, III. Department of Medicine, University Medical Center Hamburg-Eppendorf (UKE), Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Zecher+BF%22">Zecher BF</searchLink>; Research Department Virus Immunology, Leibniz Institute of Virology, Hamburg, Germany.; I. Department of Medicine, University Medical Centre Hamburg-Eppendorf, Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Hoelzemer+A%22">Hoelzemer A</searchLink>; I. Department of Medicine, University Medical Centre Hamburg-Eppendorf, Hamburg, Germany.; Institute for Infection Research and Vaccine Development (IIRVD), University Medical Centre Hamburg-Eppendorf, Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Linder+S%22">Linder S</searchLink>; Institute for Medical Microbiology, Virology and Hygiene, University Medical Centre Hamburg-Eppendorf, Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Arnberg+N%22">Arnberg N</searchLink>; Research Department of Clinical Microbiology, Umeå University, Umeå, Sweden.; Umeå Centre for Microbial Research (UCMR), Umeå University, Umeå, Sweden.; Molecular Infection Biology Sweden (MIMS), Umeå University, Umeå, Sweden.; Science for Life Laboratory (SciLifeLab), Umeå University, Umeå, Sweden.<br /><searchLink fieldCode="AU" term="%22Dobner+T%22">Dobner T</searchLink>; Research Department Viral Transformation, Leibniz Institute of Virology, Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Altfeld+M%22">Altfeld M</searchLink>; Research Department Virus Immunology, Leibniz Institute of Virology, Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Schloer+S%22">Schloer S</searchLink>; Research Department Virus Immunology, Leibniz Institute of Virology, Hamburg, Germany.; Institute of Immunology, University Medical Centre Hamburg-Eppendorf, Hamburg, Germany.
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