Bacteriophage lysin P26ly combats multidrug-resistant Escherichia coli O157 and methicillin-resistant Staphylococcus aureus via cell wall degradation and membrane disruption.

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Title: Bacteriophage lysin P26ly combats multidrug-resistant Escherichia coli O157 and methicillin-resistant Staphylococcus aureus via cell wall degradation and membrane disruption.
Authors: Zhu GS; Faculty of Life Science and Technology, Kunming University of Science and Technology, Kunming, 650500, China., Yang XX; Faculty of Life Science and Technology, Kunming University of Science and Technology, Kunming, 650500, China., Zhang Y; Faculty of Life Science and Technology, Kunming University of Science and Technology, Kunming, 650500, China., Zhang XY; Faculty of Life Science and Technology, Kunming University of Science and Technology, Kunming, 650500, China., Lin LB; Faculty of Life Science and Technology, Kunming University of Science and Technology, Kunming, 650500, China; Engineering Research Center for Replacement Technology of Feed Antibiotics of Yunnan College, Kunming, 650500, China. Electronic address: linlb@kust.edu.cn., Wang F; Faculty of Life Science and Technology, Kunming University of Science and Technology, Kunming, 650500, China; Engineering Research Center for Replacement Technology of Feed Antibiotics of Yunnan College, Kunming, 650500, China. Electronic address: wangf@kust.edu.cn.
Source: International journal of biological macromolecules [Int J Biol Macromol] 2026 Jan; Vol. 336, pp. 149288. Date of Electronic Publication: 2025 Nov 27.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 7909578 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0003 (Electronic) Linking ISSN: 01418130 NLM ISO Abbreviation: Int J Biol Macromol Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1879-0003
DOI:10.1016/j.ijbiomac.2025.149288