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ERK-mTOR crosstalk suppresses autophagy and upregulates proteasomal degradation pathway to confer chronic myeloid leukemia cells resistant to imatinib.

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Title: ERK-mTOR crosstalk suppresses autophagy and upregulates proteasomal degradation pathway to confer chronic myeloid leukemia cells resistant to imatinib.
Authors: Roy R; Department of Life Sciences, Presidency University, Kolkata, India., Paul T; Department of Life Sciences, Presidency University, Kolkata, India., Das PK; Department of Life Sciences, Presidency University, Kolkata, India., Sinha S; Department of Life Sciences, Presidency University, Kolkata, India., Ray SS; Institute of Hematology & Transfusion Medicine, Medical College Kolkata, India., Bhattacharyya M; Institute of Hematology & Transfusion Medicine, Medical College Kolkata, India., Biswas N; Department of Life Sciences, Presidency University, Kolkata, India. Electronic address: nabendu.dbs@presiuniv.ac.in.
Source: Experimental hematology [Exp Hematol] 2026 Feb; Vol. 154, pp. 105330. Date of Electronic Publication: 2025 Nov 28.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Science Inc Country of Publication: Netherlands NLM ID: 0402313 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-2399 (Electronic) Linking ISSN: 0301472X NLM ISO Abbreviation: Exp Hematol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: ERK-mTOR crosstalk suppresses autophagy and upregulates proteasomal degradation pathway to confer chronic myeloid leukemia cells resistant to imatinib.
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  Data: <searchLink fieldCode="AU" term="%22Roy+R%22">Roy R</searchLink>; Department of Life Sciences, Presidency University, Kolkata, India.<br /><searchLink fieldCode="AU" term="%22Paul+T%22">Paul T</searchLink>; Department of Life Sciences, Presidency University, Kolkata, India.<br /><searchLink fieldCode="AU" term="%22Das+PK%22">Das PK</searchLink>; Department of Life Sciences, Presidency University, Kolkata, India.<br /><searchLink fieldCode="AU" term="%22Sinha+S%22">Sinha S</searchLink>; Department of Life Sciences, Presidency University, Kolkata, India.<br /><searchLink fieldCode="AU" term="%22Ray+SS%22">Ray SS</searchLink>; Institute of Hematology & Transfusion Medicine, Medical College Kolkata, India.<br /><searchLink fieldCode="AU" term="%22Bhattacharyya+M%22">Bhattacharyya M</searchLink>; Institute of Hematology & Transfusion Medicine, Medical College Kolkata, India.<br /><searchLink fieldCode="AU" term="%22Biswas+N%22">Biswas N</searchLink>; Department of Life Sciences, Presidency University, Kolkata, India. Electronic address: nabendu.dbs@presiuniv.ac.in.
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  Data: <searchLink fieldCode="JN" term="%220402313%22">Experimental hematology</searchLink> [Exp Hematol] 2026 Feb; Vol. 154, pp. 105330. <i>Date of Electronic Publication: </i>2025 Nov 28.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier+Science+Inc%22">Elsevier Science Inc </searchLink><i>Country of Publication: </i>Netherlands <i>NLM ID: </i>0402313 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1873-2399 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%220301472X%22">0301472X </searchLink><i>NLM ISO Abbreviation: </i>Exp Hematol <i>Subsets: </i>MEDLINE
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      – Type: doi
        Value: 10.1016/j.exphem.2025.105330
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      – Code: eng
        Text: English
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      – TitleFull: ERK-mTOR crosstalk suppresses autophagy and upregulates proteasomal degradation pathway to confer chronic myeloid leukemia cells resistant to imatinib.
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            NameFull: Roy R
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            NameFull: Paul T
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            NameFull: Sinha S
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            NameFull: Bhattacharyya M
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              Text: 2026 Feb
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              Y: 2026
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              Value: 154
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            – TitleFull: Experimental hematology
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