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Towards an AI biomedical scientist: Accelerating discoveries in neurodegenerative disease.

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Title: Towards an AI biomedical scientist: Accelerating discoveries in neurodegenerative disease.
Authors: Roberts KF; Department of Pathology & Immunology, Washington University, St. Louis, MO, USA; Consortium for Biomedical Research and Artificial Intelligence in Neurodegeneration (C-brAIn)., Landsness EC; Department of Neurology, Washington University, St. Louis, MO, USA; Consortium for Biomedical Research and Artificial Intelligence in Neurodegeneration (C-brAIn)., Reese J; Environmental Genomics and Systems Biology Division, Lawrence Berkeley National Laboratory, Berkeley, CA, USA; Consortium for Biomedical Research and Artificial Intelligence in Neurodegeneration (C-brAIn)., Elbert D; Department of Neurology, University of Washington, Seattle, WA, USA; Consortium for Biomedical Research and Artificial Intelligence in Neurodegeneration (C-brAIn)., Strobel G; Alzforum Foundation Inc., MA, USA; Consortium for Biomedical Research and Artificial Intelligence in Neurodegeneration (C-brAIn)., Wu E; Alzforum Foundation Inc., MA, USA; Consortium for Biomedical Research and Artificial Intelligence in Neurodegeneration (C-brAIn)., Chen Y; Department of Computer Science & Engineering, Washington University, St. Louis, MO, USA; Consortium for Biomedical Research and Artificial Intelligence in Neurodegeneration (C-brAIn)., Lai A; Department of Computer Science & Engineering, Washington University, St. Louis, MO, USA; Institute for Informatics, Data Science and Biostatistics (I2DB), Washington University, St. Louis, MO, USA., Abrams ZB; Institute for Informatics, Data Science and Biostatistics (I2DB), Washington University, St. Louis, MO, USA; Consortium for Biomedical Research and Artificial Intelligence in Neurodegeneration (C-brAIn)., Zhu M; Department of Computer Science & Engineering, Washington University, St. Louis, MO, USA., Melendez J; Department of Neurology, Washington University, St. Louis, MO, USA; Tracy Family SILQ Center, Washington University, St. Louis, MO, USA; Consortium for Biomedical Research and Artificial Intelligence in Neurodegeneration (C-brAIn)., Koutarapu S; Department of Neurology, Washington University, St. Louis, MO, USA; Consortium for Biomedical Research and Artificial Intelligence in Neurodegeneration (C-brAIn)., Song S; Department of Neurology, Washington University, St. Louis, MO, USA; Consortium for Biomedical Research and Artificial Intelligence in Neurodegeneration (C-brAIn)., Chen Y; Department of Neurology, Washington University, St. Louis, MO, USA; Consortium for Biomedical Research and Artificial Intelligence in Neurodegeneration (C-brAIn)., Lazar R; Booz Allen Hamilton., Barnaghi P; Department of Brain Sciences, Imperial College London, London, England United Kingdom., Crary JF; Department of Pathology, Nash Family Department of Neuroscience, Department of Artificial Intelligence & Human Health, Neuropathology Brain Bank & Research CoRE, Ronald M. Loeb Center for Alzheimer's Disease, Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, NY, NY, USA., Sardi SP; Sanofi, Cambridge, MA, USA; Consortium for Biomedical Research and Artificial Intelligence in Neurodegeneration (C-brAIn)., Voss MD; Sanofi, Cambridge, MA, USA., Krishnan R; Sanofi, Cambridge, MA, USA., Schwartz JW; Bristol Myers Squibb, Cambridge, MA, USA., Mallon R; Department of Philosophy, Washington University, St. Louis, MO, USA; Consortium for Biomedical Research and Artificial Intelligence in Neurodegeneration (C-brAIn)., Jimenez-Maggiora GA; Alzheimer's Therapeutic Research Institute, Keck School of Medicine of University of Southern California, San Diego, CA, USA; Consortium for Biomedical Research and Artificial Intelligence in Neurodegeneration (C-brAIn)., Wang C; Department of Computer Science and Engineering, University of California Santa Cruz, CA, USA; Consortium for Biomedical Research and Artificial Intelligence in Neurodegeneration (C-brAIn)., Sandmann T; Denali Therapeutics Inc., South San Francisco, CA, USA; Consortium for Biomedical Research and Artificial Intelligence in Neurodegeneration (C-brAIn)., Bose N; Alzheimer's Disease Data Initiative, USA; Sage Bionetworks, USA., Phatak M; The 10,000 Brains Project, USA; Consortium for Biomedical Research and Artificial Intelligence in Neurodegeneration (C-brAIn)., Wittenberg G; Johnson & Johnson, USA., Kevrekidis YG; Department of Chemical and Biomolecular Engineering, Johns Hopkins University, Baltimore, MD, USA; Consortium for Biomedical Research and Artificial Intelligence in Neurodegeneration (C-brAIn)., Mitchell CS; Department of Biomedical Engineering, Georgia Institute of Technology, Atlanta, GA, USA., Mitchener L; FutureHouse, USA., Raj T; Department of Neuroscience, Icahn School of Medicine at Mount Sinai, NY, NY, USA., Foschini L; Sage Bionetworks, USA; Consortium for Biomedical Research and Artificial Intelligence in Neurodegeneration (C-brAIn)., Moore GJ; Gates Ventures, USA; Consortium for Biomedical Research and Artificial Intelligence in Neurodegeneration (C-brAIn)., Bateman RJ; Department of Neurology, Washington University, St. Louis, MO, USA; Tracy Family SILQ Center, Washington University, St. Louis, MO, USA; Consortium for Biomedical Research and Artificial Intelligence in Neurodegeneration (C-brAIn). Electronic address: batemanr@wustl.edu.
Source: The journal of prevention of Alzheimer's disease [J Prev Alzheimers Dis] 2025 Dec 01, pp. 100398. Date of Electronic Publication: 2025 Dec 01.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 101638820 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2426-0266 (Electronic) Linking ISSN: 22745807 NLM ISO Abbreviation: J Prev Alzheimers Dis Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Towards an AI biomedical scientist: Accelerating discoveries in neurodegenerative disease.
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  Data: <searchLink fieldCode="AU" term="%22Roberts+KF%22">Roberts KF</searchLink>; Department of Pathology & Immunology, Washington University, St. Louis, MO, USA; Consortium for Biomedical Research and Artificial Intelligence in Neurodegeneration (C-brAIn).<br /><searchLink fieldCode="AU" term="%22Landsness+EC%22">Landsness EC</searchLink>; Department of Neurology, Washington University, St. Louis, MO, USA; Consortium for Biomedical Research and Artificial Intelligence in Neurodegeneration (C-brAIn).<br /><searchLink fieldCode="AU" term="%22Reese+J%22">Reese J</searchLink>; Environmental Genomics and Systems Biology Division, Lawrence Berkeley National Laboratory, Berkeley, CA, USA; Consortium for Biomedical Research and Artificial Intelligence in Neurodegeneration (C-brAIn).<br /><searchLink fieldCode="AU" term="%22Elbert+D%22">Elbert D</searchLink>; Department of Neurology, University of Washington, Seattle, WA, USA; Consortium for Biomedical Research and Artificial Intelligence in Neurodegeneration (C-brAIn).<br /><searchLink fieldCode="AU" term="%22Strobel+G%22">Strobel G</searchLink>; Alzforum Foundation Inc., MA, USA; Consortium for Biomedical Research and Artificial Intelligence in Neurodegeneration (C-brAIn).<br /><searchLink fieldCode="AU" term="%22Wu+E%22">Wu E</searchLink>; Alzforum Foundation Inc., MA, USA; Consortium for Biomedical Research and Artificial Intelligence in Neurodegeneration (C-brAIn).<br /><searchLink fieldCode="AU" term="%22Chen+Y%22">Chen Y</searchLink>; Department of Computer Science & Engineering, Washington University, St. Louis, MO, USA; Consortium for Biomedical Research and Artificial Intelligence in Neurodegeneration (C-brAIn).<br /><searchLink fieldCode="AU" term="%22Lai+A%22">Lai A</searchLink>; Department of Computer Science & Engineering, Washington University, St. Louis, MO, USA; Institute for Informatics, Data Science and Biostatistics (I2DB), Washington University, St. Louis, MO, USA.<br /><searchLink fieldCode="AU" term="%22Abrams+ZB%22">Abrams ZB</searchLink>; Institute for Informatics, Data Science and Biostatistics (I2DB), Washington University, St. Louis, MO, USA; Consortium for Biomedical Research and Artificial Intelligence in Neurodegeneration (C-brAIn).<br /><searchLink fieldCode="AU" term="%22Zhu+M%22">Zhu M</searchLink>; Department of Computer Science & Engineering, Washington University, St. Louis, MO, USA.<br /><searchLink fieldCode="AU" term="%22Melendez+J%22">Melendez J</searchLink>; Department of Neurology, Washington University, St. Louis, MO, USA; Tracy Family SILQ Center, Washington University, St. Louis, MO, USA; Consortium for Biomedical Research and Artificial Intelligence in Neurodegeneration (C-brAIn).<br /><searchLink fieldCode="AU" term="%22Koutarapu+S%22">Koutarapu S</searchLink>; Department of Neurology, Washington University, St. Louis, MO, USA; Consortium for Biomedical Research and Artificial Intelligence in Neurodegeneration (C-brAIn).<br /><searchLink fieldCode="AU" term="%22Song+S%22">Song S</searchLink>; Department of Neurology, Washington University, St. Louis, MO, USA; Consortium for Biomedical Research and Artificial Intelligence in Neurodegeneration (C-brAIn).<br /><searchLink fieldCode="AU" term="%22Chen+Y%22">Chen Y</searchLink>; Department of Neurology, Washington University, St. Louis, MO, USA; Consortium for Biomedical Research and Artificial Intelligence in Neurodegeneration (C-brAIn).<br /><searchLink fieldCode="AU" term="%22Lazar+R%22">Lazar R</searchLink>; Booz Allen Hamilton.<br /><searchLink fieldCode="AU" term="%22Barnaghi+P%22">Barnaghi P</searchLink>; Department of Brain Sciences, Imperial College London, London, England United Kingdom.<br /><searchLink fieldCode="AU" term="%22Crary+JF%22">Crary JF</searchLink>; Department of Pathology, Nash Family Department of Neuroscience, Department of Artificial Intelligence & Human Health, Neuropathology Brain Bank & Research CoRE, Ronald M. Loeb Center for Alzheimer's Disease, Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, NY, NY, USA.<br /><searchLink fieldCode="AU" term="%22Sardi+SP%22">Sardi SP</searchLink>; Sanofi, Cambridge, MA, USA; Consortium for Biomedical Research and Artificial Intelligence in Neurodegeneration (C-brAIn).<br /><searchLink fieldCode="AU" term="%22Voss+MD%22">Voss MD</searchLink>; Sanofi, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Krishnan+R%22">Krishnan R</searchLink>; Sanofi, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Schwartz+JW%22">Schwartz JW</searchLink>; Bristol Myers Squibb, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Mallon+R%22">Mallon R</searchLink>; Department of Philosophy, Washington University, St. Louis, MO, USA; Consortium for Biomedical Research and Artificial Intelligence in Neurodegeneration (C-brAIn).<br /><searchLink fieldCode="AU" term="%22Jimenez-Maggiora+GA%22">Jimenez-Maggiora GA</searchLink>; Alzheimer's Therapeutic Research Institute, Keck School of Medicine of University of Southern California, San Diego, CA, USA; Consortium for Biomedical Research and Artificial Intelligence in Neurodegeneration (C-brAIn).<br /><searchLink fieldCode="AU" term="%22Wang+C%22">Wang C</searchLink>; Department of Computer Science and Engineering, University of California Santa Cruz, CA, USA; Consortium for Biomedical Research and Artificial Intelligence in Neurodegeneration (C-brAIn).<br /><searchLink fieldCode="AU" term="%22Sandmann+T%22">Sandmann T</searchLink>; Denali Therapeutics Inc., South San Francisco, CA, USA; Consortium for Biomedical Research and Artificial Intelligence in Neurodegeneration (C-brAIn).<br /><searchLink fieldCode="AU" term="%22Bose+N%22">Bose N</searchLink>; Alzheimer's Disease Data Initiative, USA; Sage Bionetworks, USA.<br /><searchLink fieldCode="AU" term="%22Phatak+M%22">Phatak M</searchLink>; The 10,000 Brains Project, USA; Consortium for Biomedical Research and Artificial Intelligence in Neurodegeneration (C-brAIn).<br /><searchLink fieldCode="AU" term="%22Wittenberg+G%22">Wittenberg G</searchLink>; Johnson & Johnson, USA.<br /><searchLink fieldCode="AU" term="%22Kevrekidis+YG%22">Kevrekidis YG</searchLink>; Department of Chemical and Biomolecular Engineering, Johns Hopkins University, Baltimore, MD, USA; Consortium for Biomedical Research and Artificial Intelligence in Neurodegeneration (C-brAIn).<br /><searchLink fieldCode="AU" term="%22Mitchell+CS%22">Mitchell CS</searchLink>; Department of Biomedical Engineering, Georgia Institute of Technology, Atlanta, GA, USA.<br /><searchLink fieldCode="AU" term="%22Mitchener+L%22">Mitchener L</searchLink>; FutureHouse, USA.<br /><searchLink fieldCode="AU" term="%22Raj+T%22">Raj T</searchLink>; Department of Neuroscience, Icahn School of Medicine at Mount Sinai, NY, NY, USA.<br /><searchLink fieldCode="AU" term="%22Foschini+L%22">Foschini L</searchLink>; Sage Bionetworks, USA; Consortium for Biomedical Research and Artificial Intelligence in Neurodegeneration (C-brAIn).<br /><searchLink fieldCode="AU" term="%22Moore+GJ%22">Moore GJ</searchLink>; Gates Ventures, USA; Consortium for Biomedical Research and Artificial Intelligence in Neurodegeneration (C-brAIn).<br /><searchLink fieldCode="AU" term="%22Bateman+RJ%22">Bateman RJ</searchLink>; Department of Neurology, Washington University, St. Louis, MO, USA; Tracy Family SILQ Center, Washington University, St. Louis, MO, USA; Consortium for Biomedical Research and Artificial Intelligence in Neurodegeneration (C-brAIn). Electronic address: batemanr@wustl.edu.
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