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GFER Represents a Target for Dual Disruption of Redox Homeostasis and Reactivation of the Immune Response in Pancreatic Adenocarcinoma.

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Title: GFER Represents a Target for Dual Disruption of Redox Homeostasis and Reactivation of the Immune Response in Pancreatic Adenocarcinoma.
Authors: Chen Z; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas., Ho IL; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas., Liu J; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas., Soeung M; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas., Yen EY; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas., Sainani S; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas.; MD Anderson Cancer Center UTHealth Houston Graduate School of Biomedical Sciences, Houston, Texas., Dyke CA; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas., Shah R; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas.; MD Anderson Cancer Center UTHealth Houston Graduate School of Biomedical Sciences, Houston, Texas., Kwon HJ; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas.; MD Anderson Cancer Center UTHealth Houston Graduate School of Biomedical Sciences, Houston, Texas., Han G; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas., Yan X; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas., Zhang S; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas., Srinivasan S; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas.; Translational Research to Advance Therapeutics and Innovation in Oncology (TRACTION), Therapeutics Discovery Division, The University of Texas MD Anderson Cancer Center, Houston, Texas., Rose JL; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas.; Translational Research to Advance Therapeutics and Innovation in Oncology (TRACTION), Therapeutics Discovery Division, The University of Texas MD Anderson Cancer Center, Houston, Texas., Citron F; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas., Jiang S; Translational Research to Advance Therapeutics and Innovation in Oncology (TRACTION), Therapeutics Discovery Division, The University of Texas MD Anderson Cancer Center, Houston, Texas., Chang Q; Translational Research to Advance Therapeutics and Innovation in Oncology (TRACTION), Therapeutics Discovery Division, The University of Texas MD Anderson Cancer Center, Houston, Texas., Feng N; Translational Research to Advance Therapeutics and Innovation in Oncology (TRACTION), Therapeutics Discovery Division, The University of Texas MD Anderson Cancer Center, Houston, Texas., Genovese G; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas.; Translational Research to Advance Therapeutics and Innovation in Oncology (TRACTION), Therapeutics Discovery Division, The University of Texas MD Anderson Cancer Center, Houston, Texas.; Department of Genitourinary Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas.; David H. Koch Center for Applied Research of Genitourinary Cancers, The University of Texas MD Anderson Cancer Center, Houston, Texas., Gao S; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas.; Translational Research to Advance Therapeutics and Innovation in Oncology (TRACTION), Therapeutics Discovery Division, The University of Texas MD Anderson Cancer Center, Houston, Texas., Yao W; Department of Translational Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, Texas., Wang L; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas.; UTHealth Houston Graduate School of Biomedical Sciences (GSBS), The University of Texas MD Anderson Cancer Center, Houston, Texas., Wang H; Department of Pathology, Division of Pathology/Lab Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas., Ying H; Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, University of Texas, Houston, Texas., Viale A; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas., Draetta GF; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas.
Source: Cancer research [Cancer Res] 2026 Mar 02; Vol. 86 (5), pp. 1132-1147.
Publication Type: Journal Article
Journal Info: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 2984705R Publication Model: Print Cited Medium: Internet ISSN: 1538-7445 (Electronic) Linking ISSN: 00085472 NLM ISO Abbreviation: Cancer Res Subsets: MEDLINE
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  Data: GFER Represents a Target for Dual Disruption of Redox Homeostasis and Reactivation of the Immune Response in Pancreatic Adenocarcinoma.
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  Data: <searchLink fieldCode="AU" term="%22Chen+Z%22">Chen Z</searchLink>; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas.<br /><searchLink fieldCode="AU" term="%22Ho+IL%22">Ho IL</searchLink>; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas.<br /><searchLink fieldCode="AU" term="%22Liu+J%22">Liu J</searchLink>; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas.<br /><searchLink fieldCode="AU" term="%22Soeung+M%22">Soeung M</searchLink>; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas.<br /><searchLink fieldCode="AU" term="%22Yen+EY%22">Yen EY</searchLink>; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas.<br /><searchLink fieldCode="AU" term="%22Sainani+S%22">Sainani S</searchLink>; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas.; MD Anderson Cancer Center UTHealth Houston Graduate School of Biomedical Sciences, Houston, Texas.<br /><searchLink fieldCode="AU" term="%22Dyke+CA%22">Dyke CA</searchLink>; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas.<br /><searchLink fieldCode="AU" term="%22Shah+R%22">Shah R</searchLink>; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas.; MD Anderson Cancer Center UTHealth Houston Graduate School of Biomedical Sciences, Houston, Texas.<br /><searchLink fieldCode="AU" term="%22Kwon+HJ%22">Kwon HJ</searchLink>; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas.; MD Anderson Cancer Center UTHealth Houston Graduate School of Biomedical Sciences, Houston, Texas.<br /><searchLink fieldCode="AU" term="%22Han+G%22">Han G</searchLink>; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas.<br /><searchLink fieldCode="AU" term="%22Yan+X%22">Yan X</searchLink>; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas.<br /><searchLink fieldCode="AU" term="%22Zhang+S%22">Zhang S</searchLink>; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas.<br /><searchLink fieldCode="AU" term="%22Srinivasan+S%22">Srinivasan S</searchLink>; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas.; Translational Research to Advance Therapeutics and Innovation in Oncology (TRACTION), Therapeutics Discovery Division, The University of Texas MD Anderson Cancer Center, Houston, Texas.<br /><searchLink fieldCode="AU" term="%22Rose+JL%22">Rose JL</searchLink>; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas.; Translational Research to Advance Therapeutics and Innovation in Oncology (TRACTION), Therapeutics Discovery Division, The University of Texas MD Anderson Cancer Center, Houston, Texas.<br /><searchLink fieldCode="AU" term="%22Citron+F%22">Citron F</searchLink>; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas.<br /><searchLink fieldCode="AU" term="%22Jiang+S%22">Jiang S</searchLink>; Translational Research to Advance Therapeutics and Innovation in Oncology (TRACTION), Therapeutics Discovery Division, The University of Texas MD Anderson Cancer Center, Houston, Texas.<br /><searchLink fieldCode="AU" term="%22Chang+Q%22">Chang Q</searchLink>; Translational Research to Advance Therapeutics and Innovation in Oncology (TRACTION), Therapeutics Discovery Division, The University of Texas MD Anderson Cancer Center, Houston, Texas.<br /><searchLink fieldCode="AU" term="%22Feng+N%22">Feng N</searchLink>; Translational Research to Advance Therapeutics and Innovation in Oncology (TRACTION), Therapeutics Discovery Division, The University of Texas MD Anderson Cancer Center, Houston, Texas.<br /><searchLink fieldCode="AU" term="%22Genovese+G%22">Genovese G</searchLink>; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas.; Translational Research to Advance Therapeutics and Innovation in Oncology (TRACTION), Therapeutics Discovery Division, The University of Texas MD Anderson Cancer Center, Houston, Texas.; Department of Genitourinary Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas.; David H. Koch Center for Applied Research of Genitourinary Cancers, The University of Texas MD Anderson Cancer Center, Houston, Texas.<br /><searchLink fieldCode="AU" term="%22Gao+S%22">Gao S</searchLink>; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas.; Translational Research to Advance Therapeutics and Innovation in Oncology (TRACTION), Therapeutics Discovery Division, The University of Texas MD Anderson Cancer Center, Houston, Texas.<br /><searchLink fieldCode="AU" term="%22Yao+W%22">Yao W</searchLink>; Department of Translational Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, Texas.<br /><searchLink fieldCode="AU" term="%22Wang+L%22">Wang L</searchLink>; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas.; UTHealth Houston Graduate School of Biomedical Sciences (GSBS), The University of Texas MD Anderson Cancer Center, Houston, Texas.<br /><searchLink fieldCode="AU" term="%22Wang+H%22">Wang H</searchLink>; Department of Pathology, Division of Pathology/Lab Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas.<br /><searchLink fieldCode="AU" term="%22Ying+H%22">Ying H</searchLink>; Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, University of Texas, Houston, Texas.<br /><searchLink fieldCode="AU" term="%22Viale+A%22">Viale A</searchLink>; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas.<br /><searchLink fieldCode="AU" term="%22Draetta+GF%22">Draetta GF</searchLink>; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22American+Association+for+Cancer+Research%22">American Association for Cancer Research </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>2984705R <i>Publication Model: </i>Print <i>Cited Medium: </i>Internet <i>ISSN: </i>1538-7445 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200085472%22">00085472 </searchLink><i>NLM ISO Abbreviation: </i>Cancer Res <i>Subsets: </i>MEDLINE
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