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A genome-scale single-cell CRISPRi map of trans gene regulation across human pluripotent stem cell lines.

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Title: A genome-scale single-cell CRISPRi map of trans gene regulation across human pluripotent stem cell lines.
Authors: Feng C; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK., Peets EM; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK., Zhou Y; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK., Crepaldi L; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK., Usluer S; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK., Dunham A; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK., Braunger JM; Heidelberg University, Heidelberg, Germany., Su J; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK., Strauss ME; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK; European Bioinformatics Institute, European Molecular Biology Laboratory, Hinxton, UK., Muraro D; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK., Xian Cheam KA; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK., Bonder MJ; Deutsches Krebsforschungszentrum, Heidelberg, Germany., Nogales EG; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK., Cooper S; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK., Bassett A; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK., Leonard S; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK., Gu Y; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK., Fussing B; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK., Burke D; King's College London, London, UK., Parts L; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK. Electronic address: leopold.parts@sanger.ac.uk., Stegle O; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK; European Bioinformatics Institute, European Molecular Biology Laboratory, Hinxton, UK; Deutsches Krebsforschungszentrum, Heidelberg, Germany; European Molecular Biology Laboratory, Heidelberg, Germany. Electronic address: oliver.stegle@embl.de., Velten B; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK; Heidelberg University, Heidelberg, Germany. Electronic address: britta.velten@cos.uni-heidelberg.de.
Source: Cell genomics [Cell Genom] 2026 Feb 11; Vol. 6 (2), pp. 101076. Date of Electronic Publication: 2025 Dec 01.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier, Inc Country of Publication: United States NLM ID: 9918284260106676 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2666-979X (Electronic) Linking ISSN: 2666979X NLM ISO Abbreviation: Cell Genom Subsets: MEDLINE
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  Data: A genome-scale single-cell CRISPRi map of trans gene regulation across human pluripotent stem cell lines.
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  Data: <searchLink fieldCode="AU" term="%22Feng+C%22">Feng C</searchLink>; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK.<br /><searchLink fieldCode="AU" term="%22Peets+EM%22">Peets EM</searchLink>; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK.<br /><searchLink fieldCode="AU" term="%22Zhou+Y%22">Zhou Y</searchLink>; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK.<br /><searchLink fieldCode="AU" term="%22Crepaldi+L%22">Crepaldi L</searchLink>; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK.<br /><searchLink fieldCode="AU" term="%22Usluer+S%22">Usluer S</searchLink>; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK.<br /><searchLink fieldCode="AU" term="%22Dunham+A%22">Dunham A</searchLink>; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK.<br /><searchLink fieldCode="AU" term="%22Braunger+JM%22">Braunger JM</searchLink>; Heidelberg University, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Su+J%22">Su J</searchLink>; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK.<br /><searchLink fieldCode="AU" term="%22Strauss+ME%22">Strauss ME</searchLink>; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK; European Bioinformatics Institute, European Molecular Biology Laboratory, Hinxton, UK.<br /><searchLink fieldCode="AU" term="%22Muraro+D%22">Muraro D</searchLink>; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK.<br /><searchLink fieldCode="AU" term="%22Xian+Cheam+KA%22">Xian Cheam KA</searchLink>; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK.<br /><searchLink fieldCode="AU" term="%22Bonder+MJ%22">Bonder MJ</searchLink>; Deutsches Krebsforschungszentrum, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Nogales+EG%22">Nogales EG</searchLink>; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK.<br /><searchLink fieldCode="AU" term="%22Cooper+S%22">Cooper S</searchLink>; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK.<br /><searchLink fieldCode="AU" term="%22Bassett+A%22">Bassett A</searchLink>; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK.<br /><searchLink fieldCode="AU" term="%22Leonard+S%22">Leonard S</searchLink>; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK.<br /><searchLink fieldCode="AU" term="%22Gu+Y%22">Gu Y</searchLink>; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK.<br /><searchLink fieldCode="AU" term="%22Fussing+B%22">Fussing B</searchLink>; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK.<br /><searchLink fieldCode="AU" term="%22Burke+D%22">Burke D</searchLink>; King's College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Parts+L%22">Parts L</searchLink>; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK. Electronic address: leopold.parts@sanger.ac.uk.<br /><searchLink fieldCode="AU" term="%22Stegle+O%22">Stegle O</searchLink>; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK; European Bioinformatics Institute, European Molecular Biology Laboratory, Hinxton, UK; Deutsches Krebsforschungszentrum, Heidelberg, Germany; European Molecular Biology Laboratory, Heidelberg, Germany. Electronic address: oliver.stegle@embl.de.<br /><searchLink fieldCode="AU" term="%22Velten+B%22">Velten B</searchLink>; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK; Heidelberg University, Heidelberg, Germany. Electronic address: britta.velten@cos.uni-heidelberg.de.
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  Data: <searchLink fieldCode="JN" term="%229918284260106676%22">Cell genomics</searchLink> [Cell Genom] 2026 Feb 11; Vol. 6 (2), pp. 101076. <i>Date of Electronic Publication: </i>2025 Dec 01.
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              Text: 2026 Feb 11
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