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ctDNA detectability and representativeness in seven body liquids from patients with metastatic breast cancer.

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Title: ctDNA detectability and representativeness in seven body liquids from patients with metastatic breast cancer.
Authors: Richard F; Laboratory for Translational Breast Cancer Research, Department of Oncology, KU Leuven, Leuven, Belgium., Maetens M; Laboratory for Translational Breast Cancer Research, Department of Oncology, KU Leuven, Leuven, Belgium., Van Baelen K; Laboratory for Translational Breast Cancer Research, Department of Oncology, KU Leuven, Leuven, Belgium.; Department of Gynecological Oncology, University Hospitals Leuven, Leuven, Belgium., Borremans K; Laboratory for Translational Breast Cancer Research, Department of Oncology, KU Leuven, Leuven, Belgium.; Department of Gynecological Oncology, University Hospitals Leuven, Leuven, Belgium., Van Cauwenberge J; Laboratory for Translational Breast Cancer Research, Department of Oncology, KU Leuven, Leuven, Belgium.; Department of Gynecological Oncology, University Hospitals Leuven, Leuven, Belgium., Zels G; Laboratory for Translational Breast Cancer Research, Department of Oncology, KU Leuven, Leuven, Belgium.; Department of Pathology, University Hospitals Leuven, Leuven, Belgium., Rousseau E; Laboratory for Translational Breast Cancer Research, Department of Oncology, KU Leuven, Leuven, Belgium., Geukens T; Laboratory for Translational Breast Cancer Research, Department of Oncology, KU Leuven, Leuven, Belgium.; Department of General Medical Oncology, University Hospitals Leuven, Leuven, Belgium., De Schepper M; Laboratory for Translational Breast Cancer Research, Department of Oncology, KU Leuven, Leuven, Belgium.; Department of Pathology, University Hospitals Leuven, Leuven, Belgium., Mahdami A; Laboratory for Translational Breast Cancer Research, Department of Oncology, KU Leuven, Leuven, Belgium., Vanderheyden E; Laboratory of Translational Genetics, Department of Human Genetics, KU Leuven, Leuven, Belgium.; Center for Cancer Biology, VIB, Leuven, Belgium., Van Brussel T; Laboratory of Translational Genetics, Department of Human Genetics, KU Leuven, Leuven, Belgium.; Center for Cancer Biology, VIB, Leuven, Belgium., Nguyen HL; Laboratory for Translational Breast Cancer Research, Department of Oncology, KU Leuven, Leuven, Belgium., Pabba A; Laboratory for Translational Breast Cancer Research, Department of Oncology, KU Leuven, Leuven, Belgium., Leduc S; Laboratory for Translational Breast Cancer Research, Department of Oncology, KU Leuven, Leuven, Belgium., Izci H; Laboratory for Translational Breast Cancer Research, Department of Oncology, KU Leuven, Leuven, Belgium., Bachir I; Laboratory for Translational Breast Cancer Research, Department of Oncology, KU Leuven, Leuven, Belgium., Carette C; Laboratory for Translational Breast Cancer Research, Department of Oncology, KU Leuven, Leuven, Belgium., Hatse S; Laboratory of Experimental Oncology (LEO), Department of Oncology, KU Leuven, and Department of General Medical Oncology, University Hospitals Leuven, Leuven, Belgium., Nysen M; Laboratory of Experimental Oncology (LEO), Department of Oncology, KU Leuven, and Department of General Medical Oncology, University Hospitals Leuven, Leuven, Belgium., Vermeulen P; Laboratory for Translational Breast Cancer Research, Department of Oncology, KU Leuven, Leuven, Belgium.; Translational Cancer Research Unit, Oncology Center Antwerp, Ziekenhuis aan de Stroom, Antwerp, Belgium., Boeckx B; Laboratory of Translational Genetics, Department of Human Genetics, KU Leuven, Leuven, Belgium.; Center for Cancer Biology, VIB, Leuven, Belgium., Lambrechts D; Laboratory of Translational Genetics, Department of Human Genetics, KU Leuven, Leuven, Belgium.; Center for Cancer Biology, VIB, Leuven, Belgium., Biganzoli E; Laboratory for Translational Breast Cancer Research, Department of Oncology, KU Leuven, Leuven, Belgium.; Unit of Clinical Research and Medical Statistics, Department of Biomedical and Clinical Sciences (DIBIC) & DSRC, LITA Vialba Campus, University of Milan, Milan, Italy., Neven P; Department of Gynecological Oncology, University Hospitals Leuven, Leuven, Belgium., Wildiers H; Department of General Medical Oncology, University Hospitals Leuven, Leuven, Belgium., Van Den Bogaert W; Department of Forensic Medicine, University Hospitals Leuven, Leuven, Belgium., Demeulemeester J; Laboratory of Integrative Cancer Genomics, VIB Center for Cancer Biology, Leuven, Belgium.; Department of Oncology, KU Leuven, Leuven, Belgium., Floris G; Department of Pathology, University Hospitals Leuven, Leuven, Belgium.; Department of Pathology and Imaging, Laboratory for Translational Cell and Tissue Research, KU Leuven, Belgium., Desmedt C; Laboratory for Translational Breast Cancer Research, Department of Oncology, KU Leuven, Leuven, Belgium. christine.desmedt@kuleuven.be.
Source: Nature communications [Nat Commun] 2025 Dec 02; Vol. 16 (1), pp. 10826. Date of Electronic Publication: 2025 Dec 02.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: ctDNA detectability and representativeness in seven body liquids from patients with metastatic breast cancer.
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  Data: <searchLink fieldCode="AU" term="%22Richard+F%22">Richard F</searchLink>; Laboratory for Translational Breast Cancer Research, Department of Oncology, KU Leuven, Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Maetens+M%22">Maetens M</searchLink>; Laboratory for Translational Breast Cancer Research, Department of Oncology, KU Leuven, Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Van+Baelen+K%22">Van Baelen K</searchLink>; Laboratory for Translational Breast Cancer Research, Department of Oncology, KU Leuven, Leuven, Belgium.; Department of Gynecological Oncology, University Hospitals Leuven, Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Borremans+K%22">Borremans K</searchLink>; Laboratory for Translational Breast Cancer Research, Department of Oncology, KU Leuven, Leuven, Belgium.; Department of Gynecological Oncology, University Hospitals Leuven, Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Van+Cauwenberge+J%22">Van Cauwenberge J</searchLink>; Laboratory for Translational Breast Cancer Research, Department of Oncology, KU Leuven, Leuven, Belgium.; Department of Gynecological Oncology, University Hospitals Leuven, Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Zels+G%22">Zels G</searchLink>; Laboratory for Translational Breast Cancer Research, Department of Oncology, KU Leuven, Leuven, Belgium.; Department of Pathology, University Hospitals Leuven, Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Rousseau+E%22">Rousseau E</searchLink>; Laboratory for Translational Breast Cancer Research, Department of Oncology, KU Leuven, Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Geukens+T%22">Geukens T</searchLink>; Laboratory for Translational Breast Cancer Research, Department of Oncology, KU Leuven, Leuven, Belgium.; Department of General Medical Oncology, University Hospitals Leuven, Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22De+Schepper+M%22">De Schepper M</searchLink>; Laboratory for Translational Breast Cancer Research, Department of Oncology, KU Leuven, Leuven, Belgium.; Department of Pathology, University Hospitals Leuven, Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Mahdami+A%22">Mahdami A</searchLink>; Laboratory for Translational Breast Cancer Research, Department of Oncology, KU Leuven, Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Vanderheyden+E%22">Vanderheyden E</searchLink>; Laboratory of Translational Genetics, Department of Human Genetics, KU Leuven, Leuven, Belgium.; Center for Cancer Biology, VIB, Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Van+Brussel+T%22">Van Brussel T</searchLink>; Laboratory of Translational Genetics, Department of Human Genetics, KU Leuven, Leuven, Belgium.; Center for Cancer Biology, VIB, Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Nguyen+HL%22">Nguyen HL</searchLink>; Laboratory for Translational Breast Cancer Research, Department of Oncology, KU Leuven, Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Pabba+A%22">Pabba A</searchLink>; Laboratory for Translational Breast Cancer Research, Department of Oncology, KU Leuven, Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Leduc+S%22">Leduc S</searchLink>; Laboratory for Translational Breast Cancer Research, Department of Oncology, KU Leuven, Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Izci+H%22">Izci H</searchLink>; Laboratory for Translational Breast Cancer Research, Department of Oncology, KU Leuven, Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Bachir+I%22">Bachir I</searchLink>; Laboratory for Translational Breast Cancer Research, Department of Oncology, KU Leuven, Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Carette+C%22">Carette C</searchLink>; Laboratory for Translational Breast Cancer Research, Department of Oncology, KU Leuven, Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Hatse+S%22">Hatse S</searchLink>; Laboratory of Experimental Oncology (LEO), Department of Oncology, KU Leuven, and Department of General Medical Oncology, University Hospitals Leuven, Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Nysen+M%22">Nysen M</searchLink>; Laboratory of Experimental Oncology (LEO), Department of Oncology, KU Leuven, and Department of General Medical Oncology, University Hospitals Leuven, Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Vermeulen+P%22">Vermeulen P</searchLink>; Laboratory for Translational Breast Cancer Research, Department of Oncology, KU Leuven, Leuven, Belgium.; Translational Cancer Research Unit, Oncology Center Antwerp, Ziekenhuis aan de Stroom, Antwerp, Belgium.<br /><searchLink fieldCode="AU" term="%22Boeckx+B%22">Boeckx B</searchLink>; Laboratory of Translational Genetics, Department of Human Genetics, KU Leuven, Leuven, Belgium.; Center for Cancer Biology, VIB, Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Lambrechts+D%22">Lambrechts D</searchLink>; Laboratory of Translational Genetics, Department of Human Genetics, KU Leuven, Leuven, Belgium.; Center for Cancer Biology, VIB, Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Biganzoli+E%22">Biganzoli E</searchLink>; Laboratory for Translational Breast Cancer Research, Department of Oncology, KU Leuven, Leuven, Belgium.; Unit of Clinical Research and Medical Statistics, Department of Biomedical and Clinical Sciences (DIBIC) & DSRC, LITA Vialba Campus, University of Milan, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Neven+P%22">Neven P</searchLink>; Department of Gynecological Oncology, University Hospitals Leuven, Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Wildiers+H%22">Wildiers H</searchLink>; Department of General Medical Oncology, University Hospitals Leuven, Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Van+Den+Bogaert+W%22">Van Den Bogaert W</searchLink>; Department of Forensic Medicine, University Hospitals Leuven, Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Demeulemeester+J%22">Demeulemeester J</searchLink>; Laboratory of Integrative Cancer Genomics, VIB Center for Cancer Biology, Leuven, Belgium.; Department of Oncology, KU Leuven, Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Floris+G%22">Floris G</searchLink>; Department of Pathology, University Hospitals Leuven, Leuven, Belgium.; Department of Pathology and Imaging, Laboratory for Translational Cell and Tissue Research, KU Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Desmedt+C%22">Desmedt C</searchLink>; Laboratory for Translational Breast Cancer Research, Department of Oncology, KU Leuven, Leuven, Belgium. christine.desmedt@kuleuven.be.
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  Data: <searchLink fieldCode="JN" term="%22101528555%22">Nature communications</searchLink> [Nat Commun] 2025 Dec 02; Vol. 16 (1), pp. 10826. <i>Date of Electronic Publication: </i>2025 Dec 02.
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