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Aspartyl protease MfSAP2 is a key virulence factor in mycelial form of skin fungi Malassezia furfur.

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Title: Aspartyl protease MfSAP2 is a key virulence factor in mycelial form of skin fungi Malassezia furfur.
Authors: Chua W; Molecular Engineering Lab, Institute of Molecular and Cell Biology, Agency for Science Technology and Research, 138673, Singapore., Hei Y; Department of Chemistry, National University of Singapore, 3 Science Drive 3, Singapore 117543., Koh LF; A*STAR Skin Research Labs (A*SRL), Agency for Science, Technology and Research (A*STAR), 8A Biomedical Grove, 138648Singapore.; Skin Research Institute of Singapore (SRIS), 8A Biomedical Grove, 138648, Singapore., Yap BLH; A*STAR Skin Research Labs (A*SRL), Agency for Science, Technology and Research (A*STAR), 8A Biomedical Grove, 138648Singapore., Saw HL; Molecular Engineering Lab, Institute of Molecular and Cell Biology, Agency for Science Technology and Research, 138673, Singapore., Maciel Fernandes TH; Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, La Jolla, California, 92093, U.S.A., da Silva EB; Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, La Jolla, California, 92093, U.S.A., Goh S; Molecular Engineering Lab, Institute of Molecular and Cell Biology, Agency for Science Technology and Research, 138673, Singapore., Dawson TL; A*STAR Skin Research Labs (A*SRL), Agency for Science, Technology and Research (A*STAR), 8A Biomedical Grove, 138648Singapore.; Skin Research Institute of Singapore (SRIS), 8A Biomedical Grove, 138648, Singapore., O'Donoghue AJ; Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, La Jolla, California, 92093, U.S.A., Common JE; A*STAR Skin Research Labs (A*SRL), Agency for Science, Technology and Research (A*STAR), 8A Biomedical Grove, 138648Singapore.; Skin Research Institute of Singapore (SRIS), 8A Biomedical Grove, 138648, Singapore.; Translational and Clinical Research Institute and NIHR Newcastle Biomedical Research Centre, Newcastle University, Newcastle upon Tyne, U.K., Li H; Molecular Engineering Lab, Institute of Molecular and Cell Biology, Agency for Science Technology and Research, 138673, Singapore.; A*STAR Skin Research Labs (A*SRL), Agency for Science, Technology and Research (A*STAR), 8A Biomedical Grove, 138648Singapore.
Source: The Biochemical journal [Biochem J] 2025 Dec 24; Vol. 483 (1).
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Published by Portland Press on behalf of the Biochemical Society Country of Publication: England NLM ID: 2984726R Publication Model: Print Cited Medium: Internet ISSN: 1470-8728 (Electronic) Linking ISSN: 02646021 NLM ISO Abbreviation: Biochem J Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Aspartyl protease MfSAP2 is a key virulence factor in mycelial form of skin fungi Malassezia furfur.
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  Data: <searchLink fieldCode="AU" term="%22Chua+W%22">Chua W</searchLink>; Molecular Engineering Lab, Institute of Molecular and Cell Biology, Agency for Science Technology and Research, 138673, Singapore.<br /><searchLink fieldCode="AU" term="%22Hei+Y%22">Hei Y</searchLink>; Department of Chemistry, National University of Singapore, 3 Science Drive 3, Singapore 117543.<br /><searchLink fieldCode="AU" term="%22Koh+LF%22">Koh LF</searchLink>; A*STAR Skin Research Labs (A*SRL), Agency for Science, Technology and Research (A*STAR), 8A Biomedical Grove, 138648Singapore.; Skin Research Institute of Singapore (SRIS), 8A Biomedical Grove, 138648, Singapore.<br /><searchLink fieldCode="AU" term="%22Yap+BLH%22">Yap BLH</searchLink>; A*STAR Skin Research Labs (A*SRL), Agency for Science, Technology and Research (A*STAR), 8A Biomedical Grove, 138648Singapore.<br /><searchLink fieldCode="AU" term="%22Saw+HL%22">Saw HL</searchLink>; Molecular Engineering Lab, Institute of Molecular and Cell Biology, Agency for Science Technology and Research, 138673, Singapore.<br /><searchLink fieldCode="AU" term="%22Maciel+Fernandes+TH%22">Maciel Fernandes TH</searchLink>; Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, La Jolla, California, 92093, U.S.A.<br /><searchLink fieldCode="AU" term="%22da+Silva+EB%22">da Silva EB</searchLink>; Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, La Jolla, California, 92093, U.S.A.<br /><searchLink fieldCode="AU" term="%22Goh+S%22">Goh S</searchLink>; Molecular Engineering Lab, Institute of Molecular and Cell Biology, Agency for Science Technology and Research, 138673, Singapore.<br /><searchLink fieldCode="AU" term="%22Dawson+TL%22">Dawson TL</searchLink>; A*STAR Skin Research Labs (A*SRL), Agency for Science, Technology and Research (A*STAR), 8A Biomedical Grove, 138648Singapore.; Skin Research Institute of Singapore (SRIS), 8A Biomedical Grove, 138648, Singapore.<br /><searchLink fieldCode="AU" term="%22O'Donoghue+AJ%22">O'Donoghue AJ</searchLink>; Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, La Jolla, California, 92093, U.S.A.<br /><searchLink fieldCode="AU" term="%22Common+JE%22">Common JE</searchLink>; A*STAR Skin Research Labs (A*SRL), Agency for Science, Technology and Research (A*STAR), 8A Biomedical Grove, 138648Singapore.; Skin Research Institute of Singapore (SRIS), 8A Biomedical Grove, 138648, Singapore.; Translational and Clinical Research Institute and NIHR Newcastle Biomedical Research Centre, Newcastle University, Newcastle upon Tyne, U.K.<br /><searchLink fieldCode="AU" term="%22Li+H%22">Li H</searchLink>; Molecular Engineering Lab, Institute of Molecular and Cell Biology, Agency for Science Technology and Research, 138673, Singapore.; A*STAR Skin Research Labs (A*SRL), Agency for Science, Technology and Research (A*STAR), 8A Biomedical Grove, 138648Singapore.
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              Text: 2025 Dec 24
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