View in EDS

Molecular basis for CSB stimulation of the SNM1A DNA repair nuclease.

Saved in:
Bibliographic Details
Title: Molecular basis for CSB stimulation of the SNM1A DNA repair nuclease.
Authors: Roddan R; Department of Oncology, MRC Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, OX3 9DS, U.K., Schaich MA; Department of Pharmacology and Chemical Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.; UPMC-Hillman Cancer Center, Pittsburgh, PA, 15232, USA., Nathan WJ; Laboratory of Genome Integrity, National Cancer Institute, NIH, Bethesda, MD, USA., Kis I; Department of Oncology, MRC Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, OX3 9DS, U.K., Pierangelini A; Target Discovery Institute, Centre for Medicines Discovery, Nuffield Department of Medicine, University of Oxford, Oxford, OX3 7FZ, U.K., Henderson LR; Department of Oncology, MRC Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, OX3 9DS, U.K., van Wee R; Physical and Theoretical Chemistry, Department of Chemistry, Kavli Institute for Nanoscience Discovery, Dorothy Crowfoot Hodgkin Building, University of Oxford, South Parks Road, Oxford OX1 3QU, U.K.; Department of Physiology, Anatomy and Genetics, University of Oxford, OX1 3QX, U.K., Martin L; Department of Oncology, MRC Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, OX3 9DS, U.K., El-Sagheer A; School of Chemistry, University of Southampton, SO17 1BJ, U.K., Kukura P; Physical and Theoretical Chemistry, Department of Chemistry, Kavli Institute for Nanoscience Discovery, Dorothy Crowfoot Hodgkin Building, University of Oxford, South Parks Road, Oxford OX1 3QU, U.K., Brown T; Chemistry Research Laboratory, 12 Mansfield Road, Department of Chemistry, University of Oxford, Oxford, OX1 3TA, U.K., O'Brien D; Target Discovery Institute, Centre for Medicines Discovery, Nuffield Department of Medicine, University of Oxford, Oxford, OX3 7FZ, U.K., Newman JA; Centre for Medicines Discovery, University of Oxford, NDMRB, Oxford, OX3 7DQ, U.K., Wilson DM 3rd; Biomedical Research Institute, Hasselt University, 3590 Diepenbeek, Belgium., Schofield CJ; Chemistry Research Laboratory, 12 Mansfield Road, Department of Chemistry, University of Oxford, Oxford, OX1 3TA, U.K.; Ineos Oxford Institute for Antimicrobial Research, University of Oxford, Oxford, OX1 3TA, U.K., Van Houten B; Department of Pharmacology and Chemical Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.; UPMC-Hillman Cancer Center, Pittsburgh, PA, 15232, USA., McHugh PJ; Department of Oncology, MRC Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, OX3 9DS, U.K.
Source: Research square [Res Sq] 2025 Nov 17. Date of Electronic Publication: 2025 Nov 17.
Publication Type: Journal Article; Preprint
Journal Info: Country of Publication: United States NLM ID: 101768035 Publication Model: Electronic Cited Medium: Internet ISSN: 2693-5015 (Electronic) Linking ISSN: 26935015 NLM ISO Abbreviation: Res Sq Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
FullText Text:
  Availability: 0
Header DbId: mdl
DbLabel: MEDLINE Ultimate
An: 41333433
AccessLevel: 2
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: Molecular basis for CSB stimulation of the SNM1A DNA repair nuclease.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AU" term="%22Roddan+R%22">Roddan R</searchLink>; Department of Oncology, MRC Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, OX3 9DS, U.K.<br /><searchLink fieldCode="AU" term="%22Schaich+MA%22">Schaich MA</searchLink>; Department of Pharmacology and Chemical Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.; UPMC-Hillman Cancer Center, Pittsburgh, PA, 15232, USA.<br /><searchLink fieldCode="AU" term="%22Nathan+WJ%22">Nathan WJ</searchLink>; Laboratory of Genome Integrity, National Cancer Institute, NIH, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Kis+I%22">Kis I</searchLink>; Department of Oncology, MRC Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, OX3 9DS, U.K.<br /><searchLink fieldCode="AU" term="%22Pierangelini+A%22">Pierangelini A</searchLink>; Target Discovery Institute, Centre for Medicines Discovery, Nuffield Department of Medicine, University of Oxford, Oxford, OX3 7FZ, U.K.<br /><searchLink fieldCode="AU" term="%22Henderson+LR%22">Henderson LR</searchLink>; Department of Oncology, MRC Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, OX3 9DS, U.K.<br /><searchLink fieldCode="AU" term="%22van+Wee+R%22">van Wee R</searchLink>; Physical and Theoretical Chemistry, Department of Chemistry, Kavli Institute for Nanoscience Discovery, Dorothy Crowfoot Hodgkin Building, University of Oxford, South Parks Road, Oxford OX1 3QU, U.K.; Department of Physiology, Anatomy and Genetics, University of Oxford, OX1 3QX, U.K.<br /><searchLink fieldCode="AU" term="%22Martin+L%22">Martin L</searchLink>; Department of Oncology, MRC Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, OX3 9DS, U.K.<br /><searchLink fieldCode="AU" term="%22El-Sagheer+A%22">El-Sagheer A</searchLink>; School of Chemistry, University of Southampton, SO17 1BJ, U.K.<br /><searchLink fieldCode="AU" term="%22Kukura+P%22">Kukura P</searchLink>; Physical and Theoretical Chemistry, Department of Chemistry, Kavli Institute for Nanoscience Discovery, Dorothy Crowfoot Hodgkin Building, University of Oxford, South Parks Road, Oxford OX1 3QU, U.K.<br /><searchLink fieldCode="AU" term="%22Brown+T%22">Brown T</searchLink>; Chemistry Research Laboratory, 12 Mansfield Road, Department of Chemistry, University of Oxford, Oxford, OX1 3TA, U.K.<br /><searchLink fieldCode="AU" term="%22O'Brien+D%22">O'Brien D</searchLink>; Target Discovery Institute, Centre for Medicines Discovery, Nuffield Department of Medicine, University of Oxford, Oxford, OX3 7FZ, U.K.<br /><searchLink fieldCode="AU" term="%22Newman+JA%22">Newman JA</searchLink>; Centre for Medicines Discovery, University of Oxford, NDMRB, Oxford, OX3 7DQ, U.K.<br /><searchLink fieldCode="AU" term="%22Wilson+DM+3rd%22">Wilson DM 3rd</searchLink>; Biomedical Research Institute, Hasselt University, 3590 Diepenbeek, Belgium.<br /><searchLink fieldCode="AU" term="%22Schofield+CJ%22">Schofield CJ</searchLink>; Chemistry Research Laboratory, 12 Mansfield Road, Department of Chemistry, University of Oxford, Oxford, OX1 3TA, U.K.; Ineos Oxford Institute for Antimicrobial Research, University of Oxford, Oxford, OX1 3TA, U.K.<br /><searchLink fieldCode="AU" term="%22Van+Houten+B%22">Van Houten B</searchLink>; Department of Pharmacology and Chemical Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.; UPMC-Hillman Cancer Center, Pittsburgh, PA, 15232, USA.<br /><searchLink fieldCode="AU" term="%22McHugh+PJ%22">McHugh PJ</searchLink>; Department of Oncology, MRC Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, OX3 9DS, U.K.
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%22101768035%22">Research square</searchLink> [Res Sq] 2025 Nov 17. <i>Date of Electronic Publication: </i>2025 Nov 17.
– Name: TypePub
  Label: Publication Type
  Group: TypPub
  Data: Journal Article; Preprint
– Name: TitleSource
  Label: Journal Info
  Group: Src
  Data: <i>Country of Publication: </i>United States <i>NLM ID: </i>101768035 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2693-5015 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2226935015%22">26935015 </searchLink><i>NLM ISO Abbreviation: </i>Res Sq <i>Subsets: </i>PubMed not MEDLINE
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=41333433
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.21203/rs.3.rs-7886236/v1
    Languages:
      – Code: eng
        Text: English
    Titles:
      – TitleFull: Molecular basis for CSB stimulation of the SNM1A DNA repair nuclease.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Roddan R
      – PersonEntity:
          Name:
            NameFull: Schaich MA
      – PersonEntity:
          Name:
            NameFull: Nathan WJ
      – PersonEntity:
          Name:
            NameFull: Kis I
      – PersonEntity:
          Name:
            NameFull: Pierangelini A
      – PersonEntity:
          Name:
            NameFull: Henderson LR
      – PersonEntity:
          Name:
            NameFull: van Wee R
      – PersonEntity:
          Name:
            NameFull: Martin L
      – PersonEntity:
          Name:
            NameFull: El-Sagheer A
      – PersonEntity:
          Name:
            NameFull: Kukura P
      – PersonEntity:
          Name:
            NameFull: Brown T
      – PersonEntity:
          Name:
            NameFull: O'Brien D
      – PersonEntity:
          Name:
            NameFull: Newman JA
      – PersonEntity:
          Name:
            NameFull: Wilson DM 3rd
      – PersonEntity:
          Name:
            NameFull: Schofield CJ
      – PersonEntity:
          Name:
            NameFull: Van Houten B
      – PersonEntity:
          Name:
            NameFull: McHugh PJ
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 17
              M: 11
              Text: 2025 Nov 17
              Type: published
              Y: 2025
          Identifiers:
            – Type: issn-electronic
              Value: 2693-5015
          Titles:
            – TitleFull: Research square
              Type: main
ResultId 1