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Augmentation of DNA exonuclease TREX1 in macrophages as a therapy for cardiac ischemic injury.

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Title: Augmentation of DNA exonuclease TREX1 in macrophages as a therapy for cardiac ischemic injury.
Authors: Ibrahim AG; Cedars-Sinai Medical Center, Smidt Heart Institute, Los Angeles, CA 90048, USA., Ciullo A; Cedars-Sinai Medical Center, Smidt Heart Institute, Los Angeles, CA 90048, USA., Komuro H; Cedars-Sinai Medical Center, Smidt Heart Institute, Los Angeles, CA 90048, USA., Miyamoto K; Cedars-Sinai Medical Center, Smidt Heart Institute, Los Angeles, CA 90048, USA., Jones XM; Cedars-Sinai Medical Center, Smidt Heart Institute, Los Angeles, CA 90048, USA., Yamaguchi S; Cedars-Sinai Medical Center, Smidt Heart Institute, Los Angeles, CA 90048, USA., Tsi K; Cedars-Sinai Medical Center, Smidt Heart Institute, Los Angeles, CA 90048, USA., Anderson J; Cedars-Sinai Medical Center, Smidt Heart Institute, Los Angeles, CA 90048, USA., Godoy Coto J; Cedars-Sinai Medical Center, Smidt Heart Institute, Los Angeles, CA 90048, USA., Kitka D; Cedars-Sinai Medical Center, Smidt Heart Institute, Los Angeles, CA 90048, USA., Liao K; Cedars-Sinai Medical Center, Smidt Heart Institute, Los Angeles, CA 90048, USA., Li C; Cedars-Sinai Medical Center, Smidt Heart Institute, Los Angeles, CA 90048, USA., Rannou A; Cedars-Sinai Medical Center, Smidt Heart Institute, Los Angeles, CA 90048, USA., Nawaz A; Cedars-Sinai Medical Center, Smidt Heart Institute, Los Angeles, CA 90048, USA., Morris A; Cedars-Sinai Medical Center, Smidt Heart Institute, Los Angeles, CA 90048, USA., Marbán CH; Cedars-Sinai Medical Center, Smidt Heart Institute, Los Angeles, CA 90048, USA., Lee J; Cedars-Sinai Medical Center, Smidt Heart Institute, Los Angeles, CA 90048, USA., Manriquez N; Cedars-Sinai Medical Center, Smidt Heart Institute, Los Angeles, CA 90048, USA., Hong Y; Cedars-Sinai Medical Center, Smidt Heart Institute, Los Angeles, CA 90048, USA., Naveen Kumar A; Cedars-Sinai Medical Center, Smidt Heart Institute, Los Angeles, CA 90048, USA., Dawkins JF; Cedars-Sinai Medical Center, Smidt Heart Institute, Los Angeles, CA 90048, USA., Rogers RG; Cedars-Sinai Medical Center, Smidt Heart Institute, Los Angeles, CA 90048, USA., Marbán E; Cedars-Sinai Medical Center, Smidt Heart Institute, Los Angeles, CA 90048, USA.
Source: Science translational medicine [Sci Transl Med] 2025 Dec 03; Vol. 17 (827), pp. eadp1338. Date of Electronic Publication: 2025 Dec 03.
Publication Type: Journal Article
Journal Info: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101505086 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1946-6242 (Electronic) Linking ISSN: 19466234 NLM ISO Abbreviation: Sci Transl Med Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Augmentation of DNA exonuclease TREX1 in macrophages as a therapy for cardiac ischemic injury.
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  Data: <searchLink fieldCode="AU" term="%22Ibrahim+AG%22">Ibrahim AG</searchLink>; Cedars-Sinai Medical Center, Smidt Heart Institute, Los Angeles, CA 90048, USA.<br /><searchLink fieldCode="AU" term="%22Ciullo+A%22">Ciullo A</searchLink>; Cedars-Sinai Medical Center, Smidt Heart Institute, Los Angeles, CA 90048, USA.<br /><searchLink fieldCode="AU" term="%22Komuro+H%22">Komuro H</searchLink>; Cedars-Sinai Medical Center, Smidt Heart Institute, Los Angeles, CA 90048, USA.<br /><searchLink fieldCode="AU" term="%22Miyamoto+K%22">Miyamoto K</searchLink>; Cedars-Sinai Medical Center, Smidt Heart Institute, Los Angeles, CA 90048, USA.<br /><searchLink fieldCode="AU" term="%22Jones+XM%22">Jones XM</searchLink>; Cedars-Sinai Medical Center, Smidt Heart Institute, Los Angeles, CA 90048, USA.<br /><searchLink fieldCode="AU" term="%22Yamaguchi+S%22">Yamaguchi S</searchLink>; Cedars-Sinai Medical Center, Smidt Heart Institute, Los Angeles, CA 90048, USA.<br /><searchLink fieldCode="AU" term="%22Tsi+K%22">Tsi K</searchLink>; Cedars-Sinai Medical Center, Smidt Heart Institute, Los Angeles, CA 90048, USA.<br /><searchLink fieldCode="AU" term="%22Anderson+J%22">Anderson J</searchLink>; Cedars-Sinai Medical Center, Smidt Heart Institute, Los Angeles, CA 90048, USA.<br /><searchLink fieldCode="AU" term="%22Godoy+Coto+J%22">Godoy Coto J</searchLink>; Cedars-Sinai Medical Center, Smidt Heart Institute, Los Angeles, CA 90048, USA.<br /><searchLink fieldCode="AU" term="%22Kitka+D%22">Kitka D</searchLink>; Cedars-Sinai Medical Center, Smidt Heart Institute, Los Angeles, CA 90048, USA.<br /><searchLink fieldCode="AU" term="%22Liao+K%22">Liao K</searchLink>; Cedars-Sinai Medical Center, Smidt Heart Institute, Los Angeles, CA 90048, USA.<br /><searchLink fieldCode="AU" term="%22Li+C%22">Li C</searchLink>; Cedars-Sinai Medical Center, Smidt Heart Institute, Los Angeles, CA 90048, USA.<br /><searchLink fieldCode="AU" term="%22Rannou+A%22">Rannou A</searchLink>; Cedars-Sinai Medical Center, Smidt Heart Institute, Los Angeles, CA 90048, USA.<br /><searchLink fieldCode="AU" term="%22Nawaz+A%22">Nawaz A</searchLink>; Cedars-Sinai Medical Center, Smidt Heart Institute, Los Angeles, CA 90048, USA.<br /><searchLink fieldCode="AU" term="%22Morris+A%22">Morris A</searchLink>; Cedars-Sinai Medical Center, Smidt Heart Institute, Los Angeles, CA 90048, USA.<br /><searchLink fieldCode="AU" term="%22Marbán+CH%22">Marbán CH</searchLink>; Cedars-Sinai Medical Center, Smidt Heart Institute, Los Angeles, CA 90048, USA.<br /><searchLink fieldCode="AU" term="%22Lee+J%22">Lee J</searchLink>; Cedars-Sinai Medical Center, Smidt Heart Institute, Los Angeles, CA 90048, USA.<br /><searchLink fieldCode="AU" term="%22Manriquez+N%22">Manriquez N</searchLink>; Cedars-Sinai Medical Center, Smidt Heart Institute, Los Angeles, CA 90048, USA.<br /><searchLink fieldCode="AU" term="%22Hong+Y%22">Hong Y</searchLink>; Cedars-Sinai Medical Center, Smidt Heart Institute, Los Angeles, CA 90048, USA.<br /><searchLink fieldCode="AU" term="%22Naveen+Kumar+A%22">Naveen Kumar A</searchLink>; Cedars-Sinai Medical Center, Smidt Heart Institute, Los Angeles, CA 90048, USA.<br /><searchLink fieldCode="AU" term="%22Dawkins+JF%22">Dawkins JF</searchLink>; Cedars-Sinai Medical Center, Smidt Heart Institute, Los Angeles, CA 90048, USA.<br /><searchLink fieldCode="AU" term="%22Rogers+RG%22">Rogers RG</searchLink>; Cedars-Sinai Medical Center, Smidt Heart Institute, Los Angeles, CA 90048, USA.<br /><searchLink fieldCode="AU" term="%22Marbán+E%22">Marbán E</searchLink>; Cedars-Sinai Medical Center, Smidt Heart Institute, Los Angeles, CA 90048, USA.
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  Data: <searchLink fieldCode="JN" term="%22101505086%22">Science translational medicine</searchLink> [Sci Transl Med] 2025 Dec 03; Vol. 17 (827), pp. eadp1338. <i>Date of Electronic Publication: </i>2025 Dec 03.
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