Reactogenicity and immunogenicity following heterologous and homologous third dose COVID-19 vaccination in UK adolescents (Com-COV3): A randomised controlled non-inferiority trial.
Saved in:
| Title: | Reactogenicity and immunogenicity following heterologous and homologous third dose COVID-19 vaccination in UK adolescents (Com-COV3): A randomised controlled non-inferiority trial. |
|---|---|
| Authors: | Kelly E; Oxford Vaccine Group, NIHR Oxford Biomedical Research Centre, Department of Paediatrics, University of Oxford, Oxford, UK., Greenland M; Oxford Vaccine Group, NIHR Oxford Biomedical Research Centre, Department of Paediatrics, University of Oxford, Oxford, UK., de Whalley P; Oxford Vaccine Group, NIHR Oxford Biomedical Research Centre, Department of Paediatrics, University of Oxford, Oxford, UK., Macaulay GC; Oxford Vaccine Group, NIHR Oxford Biomedical Research Centre, Department of Paediatrics, University of Oxford, Oxford, UK., Aley PK; Oxford Vaccine Group, NIHR Oxford Biomedical Research Centre, Department of Paediatrics, University of Oxford, Oxford, UK., Plested E; Oxford Vaccine Group, NIHR Oxford Biomedical Research Centre, Department of Paediatrics, University of Oxford, Oxford, UK., Koleva S; Oxford Vaccine Group, NIHR Oxford Biomedical Research Centre, Department of Paediatrics, University of Oxford, Oxford, UK., Cotton J; Oxford Vaccine Group, NIHR Oxford Biomedical Research Centre, Department of Paediatrics, University of Oxford, Oxford, UK., Kinch J; Oxford Vaccine Group, NIHR Oxford Biomedical Research Centre, Department of Paediatrics, University of Oxford, Oxford, UK., Madupuri T; Oxford Vaccine Group, NIHR Oxford Biomedical Research Centre, Department of Paediatrics, University of Oxford, Oxford, UK., Read RC; NIHR Southampton Clinical Research Facility and Biomedical Research Centre, University Hospital Southampton NHS Foundation Trust, Southampton, UK; Faculty of Medicine and Institute for Life Sciences, University of Southampton, Southampton, UK., Ramsay M; Immunisation and Countermeasures Division, National Infection Service, Public Health England, London, UK., Cameron C; Health Protection Scotland, Glasgow, UK., Turner DPJ; University of Nottingham, UK; Nottingham University Hospitals NHS Trust, Nottingham, UK., Heath P; Vaccine Institute, St. George's, University of London and St. George's University Hospitals NHS Trust, London, UK., Connor P; Noah's Ark Children's Hospital for Wales, University Hospital of Wales, Cardiff, UK., Cathie K; NIHR Southampton Clinical Research Facility and Biomedical Research Centre, University Hospital Southampton NHS Foundation Trust, Southampton, UK., Faust SN; NIHR Southampton Clinical Research Facility and Biomedical Research Centre, University Hospital Southampton NHS Foundation Trust, Southampton, UK; Faculty of Medicine and Institute for Life Sciences, University of Southampton, Southampton, UK., Banerjee I; Royal Manchester Children's Hospital, Manchester University Hospitals Foundation Trust, UK., Man K; Royal Free Hospital NHS Foundation Trust, London, UK., Shackley F; Sheffield's Children NHS Foundation Trust, Sheffield, UK., O' Riordan S; Leeds Teaching Hospital NHS Foundation Trust, Leeds, UK., Owens S; Newcastle Upon Tyne Hospitals NHS Foundation Trust, UK., Polychronakis T; Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK., Trari Belhadef H; Oxford Vaccine Group, NIHR Oxford Biomedical Research Centre, Department of Paediatrics, University of Oxford, Oxford, UK., Mujadidi Y; Oxford Vaccine Group, NIHR Oxford Biomedical Research Centre, Department of Paediatrics, University of Oxford, Oxford, UK., Singha A; Oxford Vaccine Group, NIHR Oxford Biomedical Research Centre, Department of Paediatrics, University of Oxford, Oxford, UK., Cantrell L; Oxford Vaccine Group, NIHR Oxford Biomedical Research Centre, Department of Paediatrics, University of Oxford, Oxford, UK., Clutterbuck E; Oxford Vaccine Group, NIHR Oxford Biomedical Research Centre, Department of Paediatrics, University of Oxford, Oxford, UK., Anslow R; Oxford Vaccine Group, NIHR Oxford Biomedical Research Centre, Department of Paediatrics, University of Oxford, Oxford, UK., James T; Oxford University Hospitals NHS Foundation Trust, Oxford, UK., Hallis B; UK Health Security Agency, Porton Down, Salisbury, UK., Matheson M; UK Health Security Agency, Porton Down, Salisbury, UK., Chang L; Nuffield Department of Medicine, University of Oxford, Oxford, UK., Lambe T; Oxford Vaccine Group, NIHR Oxford Biomedical Research Centre, Department of Paediatrics, University of Oxford, Oxford, UK; Chinese Academy of Medical Science (CAMS) Oxford Institute, University of Oxford, Oxford, UK., Nguyen-Van-Tam JS; Population and Lifespan Health, University of Nottingham, Nottingham, UK., Snape MD; Oxford Vaccine Group, NIHR Oxford Biomedical Research Centre, Department of Paediatrics, University of Oxford, Oxford, UK., Minassian AM; Oxford Vaccine Group, NIHR Oxford Biomedical Research Centre, Department of Paediatrics, University of Oxford, Oxford, UK., Liu X; Oxford Vaccine Group, NIHR Oxford Biomedical Research Centre, Department of Paediatrics, University of Oxford, Oxford, UK. Electronic address: Xinxue.liu@paediatrics.ox.ac.uk. |
| Source: | The Journal of infection [J Infect] 2026 Jan; Vol. 92 (1), pp. 106663. Date of Electronic Publication: 2025 Dec 01. |
| Publication Type: | Clinical Trial, Phase II; Equivalence Trial; Journal Article; Multicenter Study |
| Journal Info: | Publisher: W.B. Saunders Country of Publication: England NLM ID: 7908424 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-2742 (Electronic) Linking ISSN: 01634453 NLM ISO Abbreviation: J Infect Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
|---|---|
| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 41338394 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
| IllustrationInfo | |
| Items | – Name: Title Label: Title Group: Ti Data: Reactogenicity and immunogenicity following heterologous and homologous third dose COVID-19 vaccination in UK adolescents (Com-COV3): A randomised controlled non-inferiority trial. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Kelly+E%22">Kelly E</searchLink>; Oxford Vaccine Group, NIHR Oxford Biomedical Research Centre, Department of Paediatrics, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Greenland+M%22">Greenland M</searchLink>; Oxford Vaccine Group, NIHR Oxford Biomedical Research Centre, Department of Paediatrics, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22de+Whalley+P%22">de Whalley P</searchLink>; Oxford Vaccine Group, NIHR Oxford Biomedical Research Centre, Department of Paediatrics, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Macaulay+GC%22">Macaulay GC</searchLink>; Oxford Vaccine Group, NIHR Oxford Biomedical Research Centre, Department of Paediatrics, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Aley+PK%22">Aley PK</searchLink>; Oxford Vaccine Group, NIHR Oxford Biomedical Research Centre, Department of Paediatrics, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Plested+E%22">Plested E</searchLink>; Oxford Vaccine Group, NIHR Oxford Biomedical Research Centre, Department of Paediatrics, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Koleva+S%22">Koleva S</searchLink>; Oxford Vaccine Group, NIHR Oxford Biomedical Research Centre, Department of Paediatrics, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Cotton+J%22">Cotton J</searchLink>; Oxford Vaccine Group, NIHR Oxford Biomedical Research Centre, Department of Paediatrics, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Kinch+J%22">Kinch J</searchLink>; Oxford Vaccine Group, NIHR Oxford Biomedical Research Centre, Department of Paediatrics, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Madupuri+T%22">Madupuri T</searchLink>; Oxford Vaccine Group, NIHR Oxford Biomedical Research Centre, Department of Paediatrics, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Read+RC%22">Read RC</searchLink>; NIHR Southampton Clinical Research Facility and Biomedical Research Centre, University Hospital Southampton NHS Foundation Trust, Southampton, UK; Faculty of Medicine and Institute for Life Sciences, University of Southampton, Southampton, UK.<br /><searchLink fieldCode="AU" term="%22Ramsay+M%22">Ramsay M</searchLink>; Immunisation and Countermeasures Division, National Infection Service, Public Health England, London, UK.<br /><searchLink fieldCode="AU" term="%22Cameron+C%22">Cameron C</searchLink>; Health Protection Scotland, Glasgow, UK.<br /><searchLink fieldCode="AU" term="%22Turner+DPJ%22">Turner DPJ</searchLink>; University of Nottingham, UK; Nottingham University Hospitals NHS Trust, Nottingham, UK.<br /><searchLink fieldCode="AU" term="%22Heath+P%22">Heath P</searchLink>; Vaccine Institute, St. George's, University of London and St. George's University Hospitals NHS Trust, London, UK.<br /><searchLink fieldCode="AU" term="%22Connor+P%22">Connor P</searchLink>; Noah's Ark Children's Hospital for Wales, University Hospital of Wales, Cardiff, UK.<br /><searchLink fieldCode="AU" term="%22Cathie+K%22">Cathie K</searchLink>; NIHR Southampton Clinical Research Facility and Biomedical Research Centre, University Hospital Southampton NHS Foundation Trust, Southampton, UK.<br /><searchLink fieldCode="AU" term="%22Faust+SN%22">Faust SN</searchLink>; NIHR Southampton Clinical Research Facility and Biomedical Research Centre, University Hospital Southampton NHS Foundation Trust, Southampton, UK; Faculty of Medicine and Institute for Life Sciences, University of Southampton, Southampton, UK.<br /><searchLink fieldCode="AU" term="%22Banerjee+I%22">Banerjee I</searchLink>; Royal Manchester Children's Hospital, Manchester University Hospitals Foundation Trust, UK.<br /><searchLink fieldCode="AU" term="%22Man+K%22">Man K</searchLink>; Royal Free Hospital NHS Foundation Trust, London, UK.<br /><searchLink fieldCode="AU" term="%22Shackley+F%22">Shackley F</searchLink>; Sheffield's Children NHS Foundation Trust, Sheffield, UK.<br /><searchLink fieldCode="AU" term="%22O'+Riordan+S%22">O' Riordan S</searchLink>; Leeds Teaching Hospital NHS Foundation Trust, Leeds, UK.<br /><searchLink fieldCode="AU" term="%22Owens+S%22">Owens S</searchLink>; Newcastle Upon Tyne Hospitals NHS Foundation Trust, UK.<br /><searchLink fieldCode="AU" term="%22Polychronakis+T%22">Polychronakis T</searchLink>; Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Trari+Belhadef+H%22">Trari Belhadef H</searchLink>; Oxford Vaccine Group, NIHR Oxford Biomedical Research Centre, Department of Paediatrics, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Mujadidi+Y%22">Mujadidi Y</searchLink>; Oxford Vaccine Group, NIHR Oxford Biomedical Research Centre, Department of Paediatrics, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Singha+A%22">Singha A</searchLink>; Oxford Vaccine Group, NIHR Oxford Biomedical Research Centre, Department of Paediatrics, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Cantrell+L%22">Cantrell L</searchLink>; Oxford Vaccine Group, NIHR Oxford Biomedical Research Centre, Department of Paediatrics, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Clutterbuck+E%22">Clutterbuck E</searchLink>; Oxford Vaccine Group, NIHR Oxford Biomedical Research Centre, Department of Paediatrics, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Anslow+R%22">Anslow R</searchLink>; Oxford Vaccine Group, NIHR Oxford Biomedical Research Centre, Department of Paediatrics, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22James+T%22">James T</searchLink>; Oxford University Hospitals NHS Foundation Trust, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Hallis+B%22">Hallis B</searchLink>; UK Health Security Agency, Porton Down, Salisbury, UK.<br /><searchLink fieldCode="AU" term="%22Matheson+M%22">Matheson M</searchLink>; UK Health Security Agency, Porton Down, Salisbury, UK.<br /><searchLink fieldCode="AU" term="%22Chang+L%22">Chang L</searchLink>; Nuffield Department of Medicine, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Lambe+T%22">Lambe T</searchLink>; Oxford Vaccine Group, NIHR Oxford Biomedical Research Centre, Department of Paediatrics, University of Oxford, Oxford, UK; Chinese Academy of Medical Science (CAMS) Oxford Institute, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Nguyen-Van-Tam+JS%22">Nguyen-Van-Tam JS</searchLink>; Population and Lifespan Health, University of Nottingham, Nottingham, UK.<br /><searchLink fieldCode="AU" term="%22Snape+MD%22">Snape MD</searchLink>; Oxford Vaccine Group, NIHR Oxford Biomedical Research Centre, Department of Paediatrics, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Minassian+AM%22">Minassian AM</searchLink>; Oxford Vaccine Group, NIHR Oxford Biomedical Research Centre, Department of Paediatrics, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Liu+X%22">Liu X</searchLink>; Oxford Vaccine Group, NIHR Oxford Biomedical Research Centre, Department of Paediatrics, University of Oxford, Oxford, UK. Electronic address: Xinxue.liu@paediatrics.ox.ac.uk. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%227908424%22">The Journal of infection</searchLink> [J Infect] 2026 Jan; Vol. 92 (1), pp. 106663. <i>Date of Electronic Publication: </i>2025 Dec 01. – Name: TypePub Label: Publication Type Group: TypPub Data: Clinical Trial, Phase II; Equivalence Trial; Journal Article; Multicenter Study – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22W%2EB%2E+Saunders%22">W.B. Saunders </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>7908424 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1532-2742 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2201634453%22">01634453 </searchLink><i>NLM ISO Abbreviation: </i>J Infect <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=41338394 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1016/j.jinf.2025.106663 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 106663 Titles: – TitleFull: Reactogenicity and immunogenicity following heterologous and homologous third dose COVID-19 vaccination in UK adolescents (Com-COV3): A randomised controlled non-inferiority trial. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Kelly E – PersonEntity: Name: NameFull: Greenland M – PersonEntity: Name: NameFull: de Whalley P – PersonEntity: Name: NameFull: Macaulay GC – PersonEntity: Name: NameFull: Aley PK – PersonEntity: Name: NameFull: Plested E – PersonEntity: Name: NameFull: Koleva S – PersonEntity: Name: NameFull: Cotton J – PersonEntity: Name: NameFull: Kinch J – PersonEntity: Name: NameFull: Madupuri T – PersonEntity: Name: NameFull: Read RC – PersonEntity: Name: NameFull: Ramsay M – PersonEntity: Name: NameFull: Cameron C – PersonEntity: Name: NameFull: Turner DPJ – PersonEntity: Name: NameFull: Heath P – PersonEntity: Name: NameFull: Connor P – PersonEntity: Name: NameFull: Cathie K – PersonEntity: Name: NameFull: Faust SN – PersonEntity: Name: NameFull: Banerjee I – PersonEntity: Name: NameFull: Man K – PersonEntity: Name: NameFull: Shackley F – PersonEntity: Name: NameFull: O' Riordan S – PersonEntity: Name: NameFull: Owens S – PersonEntity: Name: NameFull: Polychronakis T – PersonEntity: Name: NameFull: Trari Belhadef H – PersonEntity: Name: NameFull: Mujadidi Y – PersonEntity: Name: NameFull: Singha A – PersonEntity: Name: NameFull: Cantrell L – PersonEntity: Name: NameFull: Clutterbuck E – PersonEntity: Name: NameFull: Anslow R – PersonEntity: Name: NameFull: James T – PersonEntity: Name: NameFull: Hallis B – PersonEntity: Name: NameFull: Matheson M – PersonEntity: Name: NameFull: Chang L – PersonEntity: Name: NameFull: Lambe T – PersonEntity: Name: NameFull: Nguyen-Van-Tam JS – PersonEntity: Name: NameFull: Snape MD – PersonEntity: Name: NameFull: Minassian AM – PersonEntity: Name: NameFull: Liu X IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 01 Text: 2026 Jan Type: published Y: 2026 Identifiers: – Type: issn-electronic Value: 1532-2742 Numbering: – Type: volume Value: 92 – Type: issue Value: 1 Titles: – TitleFull: The Journal of infection Type: main |
| ResultId | 1 |
