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Model-based antithymocyte globulin dosing in ex vivo CD34+ selected allogeneic haematopoietic cell transplantation: a single-centre, single-arm, phase 2 study.

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Title: Model-based antithymocyte globulin dosing in ex vivo CD34+ selected allogeneic haematopoietic cell transplantation: a single-centre, single-arm, phase 2 study.
Authors: Scordo M; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA; Department of Medicine, Weill Cornell Medical College, New York, NY, USA., Perales MA; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA; Department of Medicine, Weill Cornell Medical College, New York, NY, USA., Mauguen A; Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Lin A; Department of Pharmacy, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Kunvarjee B; Department of Pharmacy, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Paes Pena M; Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Mcavoy D; Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Nguyen LK; Department of Nursing, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Hogan M; Department of Nursing, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Chapman N; Department of Nursing, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Bieler J; Department of Nursing, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Cho C; John Theurer Cancer Center, Hackensack University Medical Center, Hackensack, NJ, USA., Gyurkocza B; Fred Hutch Cancer Center, University of Washington School of Medicine, Seattle, WA, USA., Harris AC; Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, NY, USA; Department of Pediatrics, Weill Cornell Medical College, New York, NY, USA., Spitzer B; John Theurer Cancer Center, Hackensack University Medical Center, Hackensack, NJ, USA., O'Reilly RJ; Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, NY, USA; Department of Pediatrics, Weill Cornell Medical College, New York, NY, USA., Jakubowski AA; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA; Department of Medicine, Weill Cornell Medical College, New York, NY, USA., Lin RJ; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA; Department of Medicine, Weill Cornell Medical College, New York, NY, USA., Papadopoulos EB; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA; Department of Medicine, Weill Cornell Medical College, New York, NY, USA., Politikos I; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA; Department of Medicine, Weill Cornell Medical College, New York, NY, USA., Ponce DM; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA; Department of Medicine, Weill Cornell Medical College, New York, NY, USA., Shaffer BC; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA; Department of Medicine, Weill Cornell Medical College, New York, NY, USA., Shah GL; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA; Department of Medicine, Weill Cornell Medical College, New York, NY, USA., Tamari R; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA; Department of Medicine, Weill Cornell Medical College, New York, NY, USA., Giralt SA; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA; Department of Medicine, Weill Cornell Medical College, New York, NY, USA., Boelens JJ; Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, NY, USA; Department of Pediatrics, Weill Cornell Medical College, New York, NY, USA., Curran KJ; Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, NY, USA; Department of Pediatrics, Weill Cornell Medical College, New York, NY, USA. Electronic address: currank@mskcc.org.
Source: The Lancet. Haematology [Lancet Haematol] 2025 Dec; Vol. 12 (12), pp. e956-e965.
Publication Type: Journal Article; Clinical Trial, Phase II
Journal Info: Publisher: Elsevier Ltd Country of Publication: England NLM ID: 101643584 Publication Model: Print Cited Medium: Internet ISSN: 2352-3026 (Electronic) Linking ISSN: 23523026 NLM ISO Abbreviation: Lancet Haematol Subsets: MEDLINE
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  Data: Model-based antithymocyte globulin dosing in ex vivo CD34+ selected allogeneic haematopoietic cell transplantation: a single-centre, single-arm, phase 2 study.
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  Data: <searchLink fieldCode="AU" term="%22Scordo+M%22">Scordo M</searchLink>; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA; Department of Medicine, Weill Cornell Medical College, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Perales+MA%22">Perales MA</searchLink>; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA; Department of Medicine, Weill Cornell Medical College, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Mauguen+A%22">Mauguen A</searchLink>; Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Lin+A%22">Lin A</searchLink>; Department of Pharmacy, Memorial Sloan Kettering Cancer Center, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Kunvarjee+B%22">Kunvarjee B</searchLink>; Department of Pharmacy, Memorial Sloan Kettering Cancer Center, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Paes+Pena+M%22">Paes Pena M</searchLink>; Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Mcavoy+D%22">Mcavoy D</searchLink>; Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Nguyen+LK%22">Nguyen LK</searchLink>; Department of Nursing, Memorial Sloan Kettering Cancer Center, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Hogan+M%22">Hogan M</searchLink>; Department of Nursing, Memorial Sloan Kettering Cancer Center, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Chapman+N%22">Chapman N</searchLink>; Department of Nursing, Memorial Sloan Kettering Cancer Center, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Bieler+J%22">Bieler J</searchLink>; Department of Nursing, Memorial Sloan Kettering Cancer Center, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Cho+C%22">Cho C</searchLink>; John Theurer Cancer Center, Hackensack University Medical Center, Hackensack, NJ, USA.<br /><searchLink fieldCode="AU" term="%22Gyurkocza+B%22">Gyurkocza B</searchLink>; Fred Hutch Cancer Center, University of Washington School of Medicine, Seattle, WA, USA.<br /><searchLink fieldCode="AU" term="%22Harris+AC%22">Harris AC</searchLink>; Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, NY, USA; Department of Pediatrics, Weill Cornell Medical College, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Spitzer+B%22">Spitzer B</searchLink>; John Theurer Cancer Center, Hackensack University Medical Center, Hackensack, NJ, USA.<br /><searchLink fieldCode="AU" term="%22O'Reilly+RJ%22">O'Reilly RJ</searchLink>; Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, NY, USA; Department of Pediatrics, Weill Cornell Medical College, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Jakubowski+AA%22">Jakubowski AA</searchLink>; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA; Department of Medicine, Weill Cornell Medical College, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Lin+RJ%22">Lin RJ</searchLink>; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA; Department of Medicine, Weill Cornell Medical College, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Papadopoulos+EB%22">Papadopoulos EB</searchLink>; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA; Department of Medicine, Weill Cornell Medical College, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Politikos+I%22">Politikos I</searchLink>; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA; Department of Medicine, Weill Cornell Medical College, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Ponce+DM%22">Ponce DM</searchLink>; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA; Department of Medicine, Weill Cornell Medical College, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Shaffer+BC%22">Shaffer BC</searchLink>; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA; Department of Medicine, Weill Cornell Medical College, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Shah+GL%22">Shah GL</searchLink>; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA; Department of Medicine, Weill Cornell Medical College, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Tamari+R%22">Tamari R</searchLink>; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA; Department of Medicine, Weill Cornell Medical College, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Giralt+SA%22">Giralt SA</searchLink>; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA; Department of Medicine, Weill Cornell Medical College, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Boelens+JJ%22">Boelens JJ</searchLink>; Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, NY, USA; Department of Pediatrics, Weill Cornell Medical College, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Curran+KJ%22">Curran KJ</searchLink>; Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, NY, USA; Department of Pediatrics, Weill Cornell Medical College, New York, NY, USA. Electronic address: currank@mskcc.org.
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