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Malaria pigment hemozoin drives M1 pro-inflammatory macrophage polarization in vitro.

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Title: Malaria pigment hemozoin drives M1 pro-inflammatory macrophage polarization in vitro.
Authors: Perego F; Parvirlab, DipartimentDepartment of Biomedical, Surgical and Dental Sciences, University of Milan, Milan, Via Pascal 36, 20133, Italy., Parapini S; Department of Biomedical Sciences for Health, University of Milan, Via Pascal 36, 20133, Milan, Italy., Calvo-Alvarez E; Department of Pharmacological and Biomolecular Sciences 'Rodolfo Paoletti', University of Milan, Via Pascal 36, 20133, Milan, Italy., Dolci M; Parvirlab, DipartimentDepartment of Biomedical, Surgical and Dental Sciences, University of Milan, Milan, Via Pascal 36, 20133, Italy., Delbue S; Parvirlab, DipartimentDepartment of Biomedical, Surgical and Dental Sciences, University of Milan, Milan, Via Pascal 36, 20133, Italy., Ghezzi S; Viral Pathogenesis and Biosafety Unit, Division of Immunology, Transplantation and Infectious Diseases, IRCCS San Raffaele Scientific Institute, Via Olgettina 58, 20132, Milan, Italy., Vicenzi E; Viral Pathogenesis and Biosafety Unit, Division of Immunology, Transplantation and Infectious Diseases, IRCCS San Raffaele Scientific Institute, Via Olgettina 58, 20132, Milan, Italy., Poli G; Human Immuno-Virology (H.I.V.) Unit, Division of Immunology, Transplantation and Infectious Diseases, IRCCS San Raffaele Scientific Institute, Via Olgettina 58, 20132, Milan, Italy.; Vita-Salute San Raffaele University School of Medicine, Via Olgettina 58, 20132, Milan, Italy., Basilico N; Parvirlab, DipartimentDepartment of Biomedical, Surgical and Dental Sciences, University of Milan, Milan, Via Pascal 36, 20133, Italy. nicoletta.basilico@unimi.it., D'Alessandro S; Department of Pharmacological and Biomolecular Sciences 'Rodolfo Paoletti', University of Milan, Via Pascal 36, 20133, Milan, Italy.
Source: Scientific reports [Sci Rep] 2025 Dec 03; Vol. 16 (1), pp. 732. Date of Electronic Publication: 2025 Dec 03.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22Perego+F%22">Perego F</searchLink>; Parvirlab, DipartimentDepartment of Biomedical, Surgical and Dental Sciences, University of Milan, Milan, Via Pascal 36, 20133, Italy.<br /><searchLink fieldCode="AU" term="%22Parapini+S%22">Parapini S</searchLink>; Department of Biomedical Sciences for Health, University of Milan, Via Pascal 36, 20133, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Calvo-Alvarez+E%22">Calvo-Alvarez E</searchLink>; Department of Pharmacological and Biomolecular Sciences 'Rodolfo Paoletti', University of Milan, Via Pascal 36, 20133, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Dolci+M%22">Dolci M</searchLink>; Parvirlab, DipartimentDepartment of Biomedical, Surgical and Dental Sciences, University of Milan, Milan, Via Pascal 36, 20133, Italy.<br /><searchLink fieldCode="AU" term="%22Delbue+S%22">Delbue S</searchLink>; Parvirlab, DipartimentDepartment of Biomedical, Surgical and Dental Sciences, University of Milan, Milan, Via Pascal 36, 20133, Italy.<br /><searchLink fieldCode="AU" term="%22Ghezzi+S%22">Ghezzi S</searchLink>; Viral Pathogenesis and Biosafety Unit, Division of Immunology, Transplantation and Infectious Diseases, IRCCS San Raffaele Scientific Institute, Via Olgettina 58, 20132, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Vicenzi+E%22">Vicenzi E</searchLink>; Viral Pathogenesis and Biosafety Unit, Division of Immunology, Transplantation and Infectious Diseases, IRCCS San Raffaele Scientific Institute, Via Olgettina 58, 20132, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Poli+G%22">Poli G</searchLink>; Human Immuno-Virology (H.I.V.) Unit, Division of Immunology, Transplantation and Infectious Diseases, IRCCS San Raffaele Scientific Institute, Via Olgettina 58, 20132, Milan, Italy.; Vita-Salute San Raffaele University School of Medicine, Via Olgettina 58, 20132, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Basilico+N%22">Basilico N</searchLink>; Parvirlab, DipartimentDepartment of Biomedical, Surgical and Dental Sciences, University of Milan, Milan, Via Pascal 36, 20133, Italy. nicoletta.basilico@unimi.it.<br /><searchLink fieldCode="AU" term="%22D'Alessandro+S%22">D'Alessandro S</searchLink>; Department of Pharmacological and Biomolecular Sciences 'Rodolfo Paoletti', University of Milan, Via Pascal 36, 20133, Milan, Italy.
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  Data: <searchLink fieldCode="JN" term="%22101563288%22">Scientific reports</searchLink> [Sci Rep] 2025 Dec 03; Vol. 16 (1), pp. 732. <i>Date of Electronic Publication: </i>2025 Dec 03.
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              Text: 2025 Dec 03
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