Malaria pigment hemozoin drives M1 pro-inflammatory macrophage polarization in vitro.

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Title: Malaria pigment hemozoin drives M1 pro-inflammatory macrophage polarization in vitro.
Authors: Perego F; Parvirlab, DipartimentDepartment of Biomedical, Surgical and Dental Sciences, University of Milan, Milan, Via Pascal 36, 20133, Italy., Parapini S; Department of Biomedical Sciences for Health, University of Milan, Via Pascal 36, 20133, Milan, Italy., Calvo-Alvarez E; Department of Pharmacological and Biomolecular Sciences 'Rodolfo Paoletti', University of Milan, Via Pascal 36, 20133, Milan, Italy., Dolci M; Parvirlab, DipartimentDepartment of Biomedical, Surgical and Dental Sciences, University of Milan, Milan, Via Pascal 36, 20133, Italy., Delbue S; Parvirlab, DipartimentDepartment of Biomedical, Surgical and Dental Sciences, University of Milan, Milan, Via Pascal 36, 20133, Italy., Ghezzi S; Viral Pathogenesis and Biosafety Unit, Division of Immunology, Transplantation and Infectious Diseases, IRCCS San Raffaele Scientific Institute, Via Olgettina 58, 20132, Milan, Italy., Vicenzi E; Viral Pathogenesis and Biosafety Unit, Division of Immunology, Transplantation and Infectious Diseases, IRCCS San Raffaele Scientific Institute, Via Olgettina 58, 20132, Milan, Italy., Poli G; Human Immuno-Virology (H.I.V.) Unit, Division of Immunology, Transplantation and Infectious Diseases, IRCCS San Raffaele Scientific Institute, Via Olgettina 58, 20132, Milan, Italy.; Vita-Salute San Raffaele University School of Medicine, Via Olgettina 58, 20132, Milan, Italy., Basilico N; Parvirlab, DipartimentDepartment of Biomedical, Surgical and Dental Sciences, University of Milan, Milan, Via Pascal 36, 20133, Italy. nicoletta.basilico@unimi.it., D'Alessandro S; Department of Pharmacological and Biomolecular Sciences 'Rodolfo Paoletti', University of Milan, Via Pascal 36, 20133, Milan, Italy.
Source: Scientific reports [Sci Rep] 2025 Dec 03; Vol. 16 (1), pp. 732. Date of Electronic Publication: 2025 Dec 03.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2045-2322
DOI:10.1038/s41598-025-30231-x