The E2F1-HMGCR axis promotes ferroptosis resistance in immune refractory tumor cells.
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| Title: | The E2F1-HMGCR axis promotes ferroptosis resistance in immune refractory tumor cells. |
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| Authors: | Son SW; Department of Cell biology, Daegu Catholic University School of Medicine, Daegu, South Korea., Lee HJ; Department of Biochemistry and Molecular Biology, Korea university College of Medicine, Seoul, South Korea.; Department of Convergence Medicine, College of Medicine, Korea University, Seoul, South Korea.; BK21 Graduate Program, Department of Biomedical Science, Korea university College of Medicine, Seoul, South Korea., Kang N; Department of Cell biology, Daegu Catholic University School of Medicine, Daegu, South Korea., Bae S; Department of Cell biology, Daegu Catholic University School of Medicine, Daegu, South Korea., Cho E; Department of Biochemistry and Molecular Biology, Korea university College of Medicine, Seoul, South Korea.; Department of Convergence Medicine, College of Medicine, Korea University, Seoul, South Korea., Kwon H; Department of Biochemistry and Molecular Biology, Korea university College of Medicine, Seoul, South Korea.; Department of Convergence Medicine, College of Medicine, Korea University, Seoul, South Korea.; BK21 Graduate Program, Department of Biomedical Science, Korea university College of Medicine, Seoul, South Korea., Yoon DY; Department of Biochemistry and Molecular Biology, Korea university College of Medicine, Seoul, South Korea.; Department of Convergence Medicine, College of Medicine, Korea University, Seoul, South Korea.; BK21 Graduate Program, Department of Biomedical Science, Korea university College of Medicine, Seoul, South Korea., Lee C; Department of Biochemistry and Molecular Biology, Korea university College of Medicine, Seoul, South Korea.; Department of Convergence Medicine, College of Medicine, Korea University, Seoul, South Korea.; BK21 Graduate Program, Department of Biomedical Science, Korea university College of Medicine, Seoul, South Korea., Lee S; Department of Biochemistry and Molecular Biology, Korea university College of Medicine, Seoul, South Korea.; Department of Convergence Medicine, College of Medicine, Korea University, Seoul, South Korea.; BK21 Graduate Program, Department of Biomedical Science, Korea university College of Medicine, Seoul, South Korea., Son MK; Department of Biochemistry and Molecular Biology, Korea university College of Medicine, Seoul, South Korea.; Department of Convergence Medicine, College of Medicine, Korea University, Seoul, South Korea.; BK21 Graduate Program, Department of Biomedical Science, Korea university College of Medicine, Seoul, South Korea., Chae J; Department of Biochemistry and Molecular Biology, Korea university College of Medicine, Seoul, South Korea.; Department of Convergence Medicine, College of Medicine, Korea University, Seoul, South Korea.; BK21 Graduate Program, Department of Biomedical Science, Korea university College of Medicine, Seoul, South Korea., Kim S; Department of Biochemistry and Molecular Biology, Korea university College of Medicine, Seoul, South Korea.; Department of Convergence Medicine, College of Medicine, Korea University, Seoul, South Korea., Oh SJ; Department of Biochemistry and Molecular Biology, Korea university College of Medicine, Seoul, South Korea.; Department of Convergence Medicine, College of Medicine, Korea University, Seoul, South Korea.; BK21 Graduate Program, Department of Biomedical Science, Korea university College of Medicine, Seoul, South Korea., Sim Y; Department of Biochemistry and Molecular Biology, Korea university College of Medicine, Seoul, South Korea.; Department of Convergence Medicine, College of Medicine, Korea University, Seoul, South Korea., Lee KM; Department of Biochemistry and Molecular Biology, Korea university College of Medicine, Seoul, South Korea.; Department of Convergence Medicine, College of Medicine, Korea University, Seoul, South Korea.; BK21 Graduate Program, Department of Biomedical Science, Korea university College of Medicine, Seoul, South Korea., Yee C; Department of Melanoma Medical Oncology and Immunology, U.T. MD Anderson Cancer Center, Houston, TX, USA., Woo SR; Department of Cell biology, Daegu Catholic University School of Medicine, Daegu, South Korea., Jeong YJ; Department of Cell biology, Daegu Catholic University School of Medicine, Daegu, South Korea., Choi HJ; Department of Cell biology, Daegu Catholic University School of Medicine, Daegu, South Korea.; Jin BioCell Co. Ltd. R&D Center, Yangsan, South Korea., Kwak JY; Department of Pharmacology, School of Medicine, Ajou University, Suwon, South Korea., Lee EW; Metabolic Regulation Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Daejeon, South Korea., Park J; Department of Cell biology, Daegu Catholic University School of Medicine, Daegu, South Korea.; Department of Medicine, Daegu Catholic University School of Medicine, Daegu, South Korea., Kwak SG; Department of Medical Statistics, Daegu Catholic University School of Medicine, Daegu, South Korea., Chang YC; Department of Cell biology, Daegu Catholic University School of Medicine, Daegu, South Korea. ycchang@cu.ac.kr., Kim TW; Department of Biochemistry and Molecular Biology, Korea university College of Medicine, Seoul, South Korea. twkim0421@korea.ac.kr.; Department of Convergence Medicine, College of Medicine, Korea University, Seoul, South Korea. twkim0421@korea.ac.kr.; BK21 Graduate Program, Department of Biomedical Science, Korea university College of Medicine, Seoul, South Korea. twkim0421@korea.ac.kr., Song KH; Department of Cell biology, Daegu Catholic University School of Medicine, Daegu, South Korea. khsong@cu.ac.kr. |
| Source: | Nature communications [Nat Commun] 2025 Dec 03; Vol. 16 (1), pp. 10849. Date of Electronic Publication: 2025 Dec 03. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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