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Editorial Expression of Concern: Munc13 C2B domain is an activity-dependent Ca2+ regulator of synaptic exocytosis.

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Title: Editorial Expression of Concern: Munc13 C2B domain is an activity-dependent Ca2+ regulator of synaptic exocytosis.
Authors: Shin OH; Departments of Neuroscience, University of Texas Southwestern Medical Center, Dallas, Texas, USA.; Department of Neuroscience & Cell Biology, University of Texas Medical Branch, Galveston, Texas, USA., Lu J; Departments of Biochemistry, University of Texas Southwestern Medical Center, Dallas, Texas, USA.; Merck & Co. Inc., Rahway, New Jersey, USA., Rhee JS; Department of Membrane Biophysics, Max-Planck-Institut für Biophysikalische Chemie, Göttingen, Germany.; Department of Neuroscience, Baylor College of Medicine, Houston, Texas, USA.; Department of Molecular Neurobiology, Max-Planck-Institut für Experimentelle Medizin, Göttingen, Germany., Tomchick DR; Departments of Biochemistry, University of Texas Southwestern Medical Center, Dallas, Texas, USA., Pang ZP; Departments of Neuroscience, University of Texas Southwestern Medical Center, Dallas, Texas, USA.; Department of Molecular & Cellular Physiology, Stanford University, California, USA., Wojcik SM; Department of Molecular Neurobiology, Max-Planck-Institut für Experimentelle Medizin, Göttingen, Germany., Camacho-Perez M; Department of Neuroscience, Baylor College of Medicine, Houston, Texas, USA.; Department of Molecular & Human Genetics, Baylor College of Medicine, Houston, Texas, USA., Brose N; Department of Molecular Neurobiology, Max-Planck-Institut für Experimentelle Medizin, Göttingen, Germany., Machius M; Departments of Biochemistry, University of Texas Southwestern Medical Center, Dallas, Texas, USA., Rizo J; Departments of Biochemistry, University of Texas Southwestern Medical Center, Dallas, Texas, USA. jose@arnie.swmed.edu.; Department of Pharmacology, University of Texas Southwestern Medical Center, Dallas, Texas, USA. jose@arnie.swmed.edu., Rosenmund C; Department of Membrane Biophysics, Max-Planck-Institut für Biophysikalische Chemie, Göttingen, Germany. rosenmun@bcm.tmc.edu.; Department of Neuroscience, Baylor College of Medicine, Houston, Texas, USA. rosenmun@bcm.tmc.edu.; Department of Pharmacology, University of Texas Southwestern Medical Center, Dallas, Texas, USA. rosenmun@bcm.tmc.edu., Südhof TC; Departments of Neuroscience, University of Texas Southwestern Medical Center, Dallas, Texas, USA. tcs1@stanford.edu.; Department of Molecular & Cellular Physiology, Stanford University, California, USA. tcs1@stanford.edu.; Department of Molecular Genetics, University of Texas Southwestern Medical Center, Dallas, Texas, USA. tcs1@stanford.edu.; Howard Hughes Medical Institute, University of Texas Southwestern Medical Center, Dallas, Texas, USA. tcs1@stanford.edu.; Howard Hughes Medical Institute, Stanford University, Stanford, California, USA. tcs1@stanford.edu.
Source: Nature structural & molecular biology [Nat Struct Mol Biol] 2025 Dec; Vol. 32 (12), pp. 2634.
Publication Type: Expression of Concern
Journal Info: Publisher: Nature Pub. Group Country of Publication: United States NLM ID: 101186374 Publication Model: Print Cited Medium: Internet ISSN: 1545-9985 (Electronic) Linking ISSN: 15459985 NLM ISO Abbreviation: Nat Struct Mol Biol Subsets: MEDLINE; In Process
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  Data: Editorial Expression of Concern: Munc13 C<subscript>2</subscript>B domain is an activity-dependent Ca<superscript>2+</superscript> regulator of synaptic exocytosis.
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  Data: <searchLink fieldCode="AU" term="%22Shin+OH%22">Shin OH</searchLink>; Departments of Neuroscience, University of Texas Southwestern Medical Center, Dallas, Texas, USA.; Department of Neuroscience & Cell Biology, University of Texas Medical Branch, Galveston, Texas, USA.<br /><searchLink fieldCode="AU" term="%22Lu+J%22">Lu J</searchLink>; Departments of Biochemistry, University of Texas Southwestern Medical Center, Dallas, Texas, USA.; Merck & Co. Inc., Rahway, New Jersey, USA.<br /><searchLink fieldCode="AU" term="%22Rhee+JS%22">Rhee JS</searchLink>; Department of Membrane Biophysics, Max-Planck-Institut für Biophysikalische Chemie, Göttingen, Germany.; Department of Neuroscience, Baylor College of Medicine, Houston, Texas, USA.; Department of Molecular Neurobiology, Max-Planck-Institut für Experimentelle Medizin, Göttingen, Germany.<br /><searchLink fieldCode="AU" term="%22Tomchick+DR%22">Tomchick DR</searchLink>; Departments of Biochemistry, University of Texas Southwestern Medical Center, Dallas, Texas, USA.<br /><searchLink fieldCode="AU" term="%22Pang+ZP%22">Pang ZP</searchLink>; Departments of Neuroscience, University of Texas Southwestern Medical Center, Dallas, Texas, USA.; Department of Molecular & Cellular Physiology, Stanford University, California, USA.<br /><searchLink fieldCode="AU" term="%22Wojcik+SM%22">Wojcik SM</searchLink>; Department of Molecular Neurobiology, Max-Planck-Institut für Experimentelle Medizin, Göttingen, Germany.<br /><searchLink fieldCode="AU" term="%22Camacho-Perez+M%22">Camacho-Perez M</searchLink>; Department of Neuroscience, Baylor College of Medicine, Houston, Texas, USA.; Department of Molecular & Human Genetics, Baylor College of Medicine, Houston, Texas, USA.<br /><searchLink fieldCode="AU" term="%22Brose+N%22">Brose N</searchLink>; Department of Molecular Neurobiology, Max-Planck-Institut für Experimentelle Medizin, Göttingen, Germany.<br /><searchLink fieldCode="AU" term="%22Machius+M%22">Machius M</searchLink>; Departments of Biochemistry, University of Texas Southwestern Medical Center, Dallas, Texas, USA.<br /><searchLink fieldCode="AU" term="%22Rizo+J%22">Rizo J</searchLink>; Departments of Biochemistry, University of Texas Southwestern Medical Center, Dallas, Texas, USA. jose@arnie.swmed.edu.; Department of Pharmacology, University of Texas Southwestern Medical Center, Dallas, Texas, USA. jose@arnie.swmed.edu.<br /><searchLink fieldCode="AU" term="%22Rosenmund+C%22">Rosenmund C</searchLink>; Department of Membrane Biophysics, Max-Planck-Institut für Biophysikalische Chemie, Göttingen, Germany. rosenmun@bcm.tmc.edu.; Department of Neuroscience, Baylor College of Medicine, Houston, Texas, USA. rosenmun@bcm.tmc.edu.; Department of Pharmacology, University of Texas Southwestern Medical Center, Dallas, Texas, USA. rosenmun@bcm.tmc.edu.<br /><searchLink fieldCode="AU" term="%22Südhof+TC%22">Südhof TC</searchLink>; Departments of Neuroscience, University of Texas Southwestern Medical Center, Dallas, Texas, USA. tcs1@stanford.edu.; Department of Molecular & Cellular Physiology, Stanford University, California, USA. tcs1@stanford.edu.; Department of Molecular Genetics, University of Texas Southwestern Medical Center, Dallas, Texas, USA. tcs1@stanford.edu.; Howard Hughes Medical Institute, University of Texas Southwestern Medical Center, Dallas, Texas, USA. tcs1@stanford.edu.; Howard Hughes Medical Institute, Stanford University, Stanford, California, USA. tcs1@stanford.edu.
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  Data: <searchLink fieldCode="JN" term="%22101186374%22">Nature structural & molecular biology</searchLink> [Nat Struct Mol Biol] 2025 Dec; Vol. 32 (12), pp. 2634.
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