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Integration of gut microbiome and lipid metabolism reveals the anti-cancer effects of pentadecanoic acid on bladder cancer.

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Title: Integration of gut microbiome and lipid metabolism reveals the anti-cancer effects of pentadecanoic acid on bladder cancer.
Authors: Chen YT; Key Laboratory of Environmental Medicine and Engineering of Ministry of Education, School of Public Health, Southeast University, Nanjing, 210009, China.; Department of Epidemiology & Biostatistics, School of Public Health, Southeast University, Nanjing, 210009, China., Sui J; Key Laboratory of Environmental Medicine and Engineering of Ministry of Education, School of Public Health, Southeast University, Nanjing, 210009, China.; Research Institute for Environment and Health, Nanjing University of Information Science and Technology, Nanjing, 210044, China., Yang Y; Key Laboratory of Environmental Medicine and Engineering of Ministry of Education, School of Public Health, Southeast University, Nanjing, 210009, China.; Department of Nutrition and Food Hygiene, School of Public Health, Southeast University, Nanjing, 210009, China., Zhang H; Department of Critical Care Medicine, Jinling Hospital, Medical School of Nanjing University, Nanjing, 210002, China., Wesselius A; Department of Epidemiology, School of Nutrition and Translational Research in Metabolism, Maastricht University, Maastricht, 6229ER, The Netherlands., Shen Y; Department of Gastroenterology, Ma'anshan People's Hospital, Ma'anshan, 243000, China., Qin QR; Ma'anshan Center for Disease Control and Prevention, Ma'anshan, 243000, China.; The Affiliated Ma'anshan Center for Disease Control and Prevention of Anhui Medical University, Ma'anshan, 243000, China.; Department of Epidemiology and Biostatistics, School of Public Health, Anhui Medical University, Hefei, 230032, China., Sun GJ; Key Laboratory of Environmental Medicine and Engineering of Ministry of Education, School of Public Health, Southeast University, Nanjing, 210009, China.; Department of Nutrition and Food Hygiene, School of Public Health, Southeast University, Nanjing, 210009, China., Wang SK; Key Laboratory of Environmental Medicine and Engineering of Ministry of Education, School of Public Health, Southeast University, Nanjing, 210009, China.; Department of Nutrition and Food Hygiene, School of Public Health, Southeast University, Nanjing, 210009, China., Wang XD; Nutrition and Cancer Biology Laboratory, Jean Mayer USDA Human Nutrition Research Center On Aging at Tufts University, Boston, MA, 02111, USA.; Gerald J. and Dorothy R. Friedman School of Nutrition Science and Policy, Tufts University, Boston, MA, 02111, USA., Wang S; Center for Obesity and Metabolic Diseases Research, School of Basic Medicine, The First Affiliated Hospital of Chongqing Medical University, Chongqing Medical University, Chongqing, China., Li WC; Department of Urology, Affiliated Zhongda Hospital of Southeast University, Nanjing, 210009, China., Cheng KK; Department of Applied Health Research, University of Birmingham, Birmingham, B152TT, UK., James ND; Bladder Cancer Research Centre, College of Medicine and Health, University of Birmingham, Birmingham, B152TT, UK.; Institute of Cancer Research, London, SW7 3RP, UK., Bryan RT; Bladder Cancer Research Centre, College of Medicine and Health, University of Birmingham, Birmingham, B152TT, UK., Zeegers MP; Department of Epidemiology, School of Nutrition and Translational Research in Metabolism, Maastricht University, Maastricht, 6229ER, The Netherlands., Chen L; Changzhou Medical Center, The Third Affiliated Hospital of Nanjing Medical University, Nanjing Medical University, Changzhou, 213003, China. lianminchen@njmu.edu.cn.; Department of Cardiology, The First Affiliated Hospital with Nanjing Medical University, Nanjing Medical University, Nanjing, 210029, China. lianminchen@njmu.edu.cn., Xia H; Key Laboratory of Environmental Medicine and Engineering of Ministry of Education, School of Public Health, Southeast University, Nanjing, 210009, China. huixia@seu.edu.cn.; Department of Nutrition and Food Hygiene, School of Public Health, Southeast University, Nanjing, 210009, China. huixia@seu.edu.cn., Yu EY; Key Laboratory of Environmental Medicine and Engineering of Ministry of Education, School of Public Health, Southeast University, Nanjing, 210009, China. evan.yu@maastrichtuniversity.nl.; Department of Epidemiology & Biostatistics, School of Public Health, Southeast University, Nanjing, 210009, China. evan.yu@maastrichtuniversity.nl.; Department of Epidemiology, School of Nutrition and Translational Research in Metabolism, Maastricht University, Maastricht, 6229ER, The Netherlands. evan.yu@maastrichtuniversity.nl.
Source: BMC medicine [BMC Med] 2025 Dec 03; Vol. 24 (1), pp. 10. Date of Electronic Publication: 2025 Dec 03.
Publication Type: Journal Article
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101190723 Publication Model: Electronic Cited Medium: Internet ISSN: 1741-7015 (Electronic) Linking ISSN: 17417015 NLM ISO Abbreviation: BMC Med Subsets: MEDLINE
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  Data: Integration of gut microbiome and lipid metabolism reveals the anti-cancer effects of pentadecanoic acid on bladder cancer.
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  Data: <searchLink fieldCode="AU" term="%22Chen+YT%22">Chen YT</searchLink>; Key Laboratory of Environmental Medicine and Engineering of Ministry of Education, School of Public Health, Southeast University, Nanjing, 210009, China.; Department of Epidemiology & Biostatistics, School of Public Health, Southeast University, Nanjing, 210009, China.<br /><searchLink fieldCode="AU" term="%22Sui+J%22">Sui J</searchLink>; Key Laboratory of Environmental Medicine and Engineering of Ministry of Education, School of Public Health, Southeast University, Nanjing, 210009, China.; Research Institute for Environment and Health, Nanjing University of Information Science and Technology, Nanjing, 210044, China.<br /><searchLink fieldCode="AU" term="%22Yang+Y%22">Yang Y</searchLink>; Key Laboratory of Environmental Medicine and Engineering of Ministry of Education, School of Public Health, Southeast University, Nanjing, 210009, China.; Department of Nutrition and Food Hygiene, School of Public Health, Southeast University, Nanjing, 210009, China.<br /><searchLink fieldCode="AU" term="%22Zhang+H%22">Zhang H</searchLink>; Department of Critical Care Medicine, Jinling Hospital, Medical School of Nanjing University, Nanjing, 210002, China.<br /><searchLink fieldCode="AU" term="%22Wesselius+A%22">Wesselius A</searchLink>; Department of Epidemiology, School of Nutrition and Translational Research in Metabolism, Maastricht University, Maastricht, 6229ER, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Shen+Y%22">Shen Y</searchLink>; Department of Gastroenterology, Ma'anshan People's Hospital, Ma'anshan, 243000, China.<br /><searchLink fieldCode="AU" term="%22Qin+QR%22">Qin QR</searchLink>; Ma'anshan Center for Disease Control and Prevention, Ma'anshan, 243000, China.; The Affiliated Ma'anshan Center for Disease Control and Prevention of Anhui Medical University, Ma'anshan, 243000, China.; Department of Epidemiology and Biostatistics, School of Public Health, Anhui Medical University, Hefei, 230032, China.<br /><searchLink fieldCode="AU" term="%22Sun+GJ%22">Sun GJ</searchLink>; Key Laboratory of Environmental Medicine and Engineering of Ministry of Education, School of Public Health, Southeast University, Nanjing, 210009, China.; Department of Nutrition and Food Hygiene, School of Public Health, Southeast University, Nanjing, 210009, China.<br /><searchLink fieldCode="AU" term="%22Wang+SK%22">Wang SK</searchLink>; Key Laboratory of Environmental Medicine and Engineering of Ministry of Education, School of Public Health, Southeast University, Nanjing, 210009, China.; Department of Nutrition and Food Hygiene, School of Public Health, Southeast University, Nanjing, 210009, China.<br /><searchLink fieldCode="AU" term="%22Wang+XD%22">Wang XD</searchLink>; Nutrition and Cancer Biology Laboratory, Jean Mayer USDA Human Nutrition Research Center On Aging at Tufts University, Boston, MA, 02111, USA.; Gerald J. and Dorothy R. Friedman School of Nutrition Science and Policy, Tufts University, Boston, MA, 02111, USA.<br /><searchLink fieldCode="AU" term="%22Wang+S%22">Wang S</searchLink>; Center for Obesity and Metabolic Diseases Research, School of Basic Medicine, The First Affiliated Hospital of Chongqing Medical University, Chongqing Medical University, Chongqing, China.<br /><searchLink fieldCode="AU" term="%22Li+WC%22">Li WC</searchLink>; Department of Urology, Affiliated Zhongda Hospital of Southeast University, Nanjing, 210009, China.<br /><searchLink fieldCode="AU" term="%22Cheng+KK%22">Cheng KK</searchLink>; Department of Applied Health Research, University of Birmingham, Birmingham, B152TT, UK.<br /><searchLink fieldCode="AU" term="%22James+ND%22">James ND</searchLink>; Bladder Cancer Research Centre, College of Medicine and Health, University of Birmingham, Birmingham, B152TT, UK.; Institute of Cancer Research, London, SW7 3RP, UK.<br /><searchLink fieldCode="AU" term="%22Bryan+RT%22">Bryan RT</searchLink>; Bladder Cancer Research Centre, College of Medicine and Health, University of Birmingham, Birmingham, B152TT, UK.<br /><searchLink fieldCode="AU" term="%22Zeegers+MP%22">Zeegers MP</searchLink>; Department of Epidemiology, School of Nutrition and Translational Research in Metabolism, Maastricht University, Maastricht, 6229ER, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Chen+L%22">Chen L</searchLink>; Changzhou Medical Center, The Third Affiliated Hospital of Nanjing Medical University, Nanjing Medical University, Changzhou, 213003, China. lianminchen@njmu.edu.cn.; Department of Cardiology, The First Affiliated Hospital with Nanjing Medical University, Nanjing Medical University, Nanjing, 210029, China. lianminchen@njmu.edu.cn.<br /><searchLink fieldCode="AU" term="%22Xia+H%22">Xia H</searchLink>; Key Laboratory of Environmental Medicine and Engineering of Ministry of Education, School of Public Health, Southeast University, Nanjing, 210009, China. huixia@seu.edu.cn.; Department of Nutrition and Food Hygiene, School of Public Health, Southeast University, Nanjing, 210009, China. huixia@seu.edu.cn.<br /><searchLink fieldCode="AU" term="%22Yu+EY%22">Yu EY</searchLink>; Key Laboratory of Environmental Medicine and Engineering of Ministry of Education, School of Public Health, Southeast University, Nanjing, 210009, China. evan.yu@maastrichtuniversity.nl.; Department of Epidemiology & Biostatistics, School of Public Health, Southeast University, Nanjing, 210009, China. evan.yu@maastrichtuniversity.nl.; Department of Epidemiology, School of Nutrition and Translational Research in Metabolism, Maastricht University, Maastricht, 6229ER, The Netherlands. evan.yu@maastrichtuniversity.nl.
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  Data: <searchLink fieldCode="JN" term="%22101190723%22">BMC medicine</searchLink> [BMC Med] 2025 Dec 03; Vol. 24 (1), pp. 10. <i>Date of Electronic Publication: </i>2025 Dec 03.
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              Text: 2025 Dec 03
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