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A High-Fiber, Plant-Based Diet in Myeloma Precursor Disorders: Results from the NUTRIVENTION Clinical Trial and Preclinical Vk*MYC Model.

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Title: A High-Fiber, Plant-Based Diet in Myeloma Precursor Disorders: Results from the NUTRIVENTION Clinical Trial and Preclinical Vk*MYC Model.
Authors: Shah UA; Department of Medicine, Myeloma Service, Memorial Sloan Kettering Cancer Center, New York, New York.; Weill Cornell Medical College, New York, New York., Cogrossi LL; Cellular Immunology Unit, Division of Immunology, Transplantation, and Infectious Diseases, IRCCS San Raffaele Scientific Institute, Milano, Italy.; Vita-Salute San Raffaele University , Milano, Italy., Garcés JJ; Department of Medicine, Myeloma Service, Memorial Sloan Kettering Cancer Center, New York, New York.; Computational Oncology, Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, New York., Policastro A; Cellular Immunology Unit, Division of Immunology, Transplantation, and Infectious Diseases, IRCCS San Raffaele Scientific Institute, Milano, Italy., Castro F; Department of Medicine, Myeloma Service, Memorial Sloan Kettering Cancer Center, New York, New York., Derkach A; Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, New York., Fei T; Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, New York., DeWolf S; Department of Medicine, Leukemia Service, Memorial Sloan Kettering Cancer Center, New York, New York., Grioni M; Cellular Immunology Unit, Division of Immunology, Transplantation, and Infectious Diseases, IRCCS San Raffaele Scientific Institute, Milano, Italy., Sisti S; Vita-Salute San Raffaele University , Milano, Italy.; Laboratory of Microbiology and Virology, IRCCS San Raffaele Hospital, Milan, Italy., Blaslov J; Department of Medicine, Myeloma Service, Memorial Sloan Kettering Cancer Center, New York, New York., Adintori PA; Food and Nutrition Services, Memorial Sloan Kettering Cancer Center, New York, New York., Hosszu KK; Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, New York., McAvoy D; Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, New York., Baichoo M; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York., Cross JR; Donald B. and Catherine C. Marron Cancer Metabolism Center, Sloan Kettering Institute, New York, New York., Paredes J; Beckham Research Institute, City of Hope, Los Angeles, California., Anuraj A; Department of Medicine, Myeloma Service, Memorial Sloan Kettering Cancer Center, New York, New York., Raj SS; Weill Cornell Medical College, New York, New York.; Department of Medicine, Adult Bone Marrow Transplantation Service, Memorial Sloan Kettering Cancer Center, New York, New York., Pohl C; Donald B. and Catherine C. Marron Cancer Metabolism Center, Sloan Kettering Institute, New York, New York., Zordan P; Cellular Immunology Unit, Division of Immunology, Transplantation, and Infectious Diseases, IRCCS San Raffaele Scientific Institute, Milano, Italy., Zinsmeyer V; Computational Oncology, Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, New York., Jesus Faustino Ramos RJ; Donald B. and Catherine C. Marron Cancer Metabolism Center, Sloan Kettering Institute, New York, New York., Lorenzoni M; Cellular Immunology Unit, Division of Immunology, Transplantation, and Infectious Diseases, IRCCS San Raffaele Scientific Institute, Milano, Italy., Gipson B; Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, New York., Maclachlan KH; Department of Medicine, Myeloma Service, Memorial Sloan Kettering Cancer Center, New York, New York.; Weill Cornell Medical College, New York, New York., Gradissimo A; Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, New York., Boiocchi L; Department of Pathology and Laboratory Medicine, Memorial Sloan Kettering Cancer Center, New York, New York., Aleynick N; Department of Pathology and Laboratory Medicine, Memorial Sloan Kettering Cancer Center, New York, New York., Marchigiani C; Cellular Immunology Unit, Division of Immunology, Transplantation, and Infectious Diseases, IRCCS San Raffaele Scientific Institute, Milano, Italy., Pagani S; Cellular Immunology Unit, Division of Immunology, Transplantation, and Infectious Diseases, IRCCS San Raffaele Scientific Institute, Milano, Italy., Salehi E; Department of Medicine, Breast Medicine Service, Memorial Sloan Kettering Cancer Center, New York, New York., Koche RP; Center for Epigenetics Research, Memorial Sloan Kettering Cancer Center, New York, New York., Chaligne R; Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, New York., Block T; NutritionQuest , Berkeley, California., Korde N; Department of Medicine, Myeloma Service, Memorial Sloan Kettering Cancer Center, New York, New York.; Weill Cornell Medical College, New York, New York., Tan CR; Department of Medicine, Myeloma Service, Memorial Sloan Kettering Cancer Center, New York, New York.; Weill Cornell Medical College, New York, New York., Hultcrantz M; Department of Medicine, Myeloma Service, Memorial Sloan Kettering Cancer Center, New York, New York.; Weill Cornell Medical College, New York, New York., Hassoun H; Department of Medicine, Myeloma Service, Memorial Sloan Kettering Cancer Center, New York, New York.; Weill Cornell Medical College, New York, New York., Shah GL; Weill Cornell Medical College, New York, New York.; Department of Medicine, Adult Bone Marrow Transplantation Service, Memorial Sloan Kettering Cancer Center, New York, New York., Scordo M; Weill Cornell Medical College, New York, New York.; Department of Medicine, Adult Bone Marrow Transplantation Service, Memorial Sloan Kettering Cancer Center, New York, New York., Lahoud OB; Department of Hematology and Medical Oncology, Perlmutter Cancer Center, NYU Langone Hospital, Brooklyn, New York.; Department of Medicine, NYU Grossman School of Medicine, New York, New York., Chung DJ; Weill Cornell Medical College, New York, New York.; Department of Medicine, Adult Bone Marrow Transplantation Service, Memorial Sloan Kettering Cancer Center, New York, New York., Landau HJ; Weill Cornell Medical College, New York, New York.; Department of Medicine, Adult Bone Marrow Transplantation Service, Memorial Sloan Kettering Cancer Center, New York, New York., Peled JU; Weill Cornell Medical College, New York, New York.; Department of Medicine, Adult Bone Marrow Transplantation Service, Memorial Sloan Kettering Cancer Center, New York, New York., Clementi N; Vita-Salute San Raffaele University , Milano, Italy.; Laboratory of Microbiology and Virology, IRCCS San Raffaele Hospital, Milan, Italy., Chesi M; Comprehensive Cancer Center, Mayo Clinic Arizona, Scottsdale, Arizona., Bergsagel PL; Comprehensive Cancer Center, Mayo Clinic Arizona, Scottsdale, Arizona., Mailankody S; Department of Medicine, Myeloma Service, Memorial Sloan Kettering Cancer Center, New York, New York.; Weill Cornell Medical College, New York, New York., Pollak MN; Department of Medicine and Oncology, McGill University, Montreal, Canada., D'Souza A; Medical College of Wisconsin , Milwaukee, Wisconsin., Landgren O; Division of Myeloma, Department of Medicine, Sylvester Comprehensive Cancer Center, Myeloma Division, University of Miami, Miami, Florida., Chimonas S; Center for Health Policy and Outcomes, Memorial Sloan Kettering Cancer Center, New York, New York., Giralt SA; Weill Cornell Medical College, New York, New York.; Department of Medicine, Adult Bone Marrow Transplantation Service, Memorial Sloan Kettering Cancer Center, New York, New York., Usmani SZ; Department of Medicine, Myeloma Service, Memorial Sloan Kettering Cancer Center, New York, New York.; Weill Cornell Medical College, New York, New York., Iyengar NM; Weill Cornell Medical College, New York, New York.; Department of Medicine, Breast Medicine Service, Memorial Sloan Kettering Cancer Center, New York, New York., Lesokhin AM; Department of Medicine, Myeloma Service, Memorial Sloan Kettering Cancer Center, New York, New York.; Weill Cornell Medical College, New York, New York., van den Brink MRM; City of Hope Los Angeles and National Medical Center, Los Angeles, California., Bellone M; Cellular Immunology Unit, Division of Immunology, Transplantation, and Infectious Diseases, IRCCS San Raffaele Scientific Institute, Milano, Italy.
Source: Cancer discovery [Cancer Discov] 2026 Apr 01; Vol. 16 (4), pp. 697-720.
Publication Type: Journal Article
Journal Info: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 101561693 Publication Model: Print Cited Medium: Internet ISSN: 2159-8290 (Electronic) Linking ISSN: 21598274 NLM ISO Abbreviation: Cancer Discov Subsets: MEDLINE
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  Data: A High-Fiber, Plant-Based Diet in Myeloma Precursor Disorders: Results from the NUTRIVENTION Clinical Trial and Preclinical Vk*MYC Model.
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Department of Pathology and Laboratory Medicine, Memorial Sloan Kettering Cancer Center, New York, New York.<br /><searchLink fieldCode="AU" term="%22Marchigiani+C%22">Marchigiani C</searchLink>; Cellular Immunology Unit, Division of Immunology, Transplantation, and Infectious Diseases, IRCCS San Raffaele Scientific Institute, Milano, Italy.<br /><searchLink fieldCode="AU" term="%22Pagani+S%22">Pagani S</searchLink>; Cellular Immunology Unit, Division of Immunology, Transplantation, and Infectious Diseases, IRCCS San Raffaele Scientific Institute, Milano, Italy.<br /><searchLink fieldCode="AU" term="%22Salehi+E%22">Salehi E</searchLink>; Department of Medicine, Breast Medicine Service, Memorial Sloan Kettering Cancer Center, New York, New York.<br /><searchLink fieldCode="AU" term="%22Koche+RP%22">Koche RP</searchLink>; Center for Epigenetics Research, Memorial Sloan Kettering Cancer Center, New York, New York.<br /><searchLink fieldCode="AU" term="%22Chaligne+R%22">Chaligne R</searchLink>; Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, New York.<br /><searchLink fieldCode="AU" term="%22Block+T%22">Block T</searchLink>; NutritionQuest , Berkeley, California.<br /><searchLink fieldCode="AU" term="%22Korde+N%22">Korde N</searchLink>; Department of Medicine, Myeloma Service, Memorial Sloan Kettering Cancer Center, New York, New York.; Weill Cornell Medical College, New York, New York.<br /><searchLink fieldCode="AU" term="%22Tan+CR%22">Tan CR</searchLink>; Department of Medicine, Myeloma Service, Memorial Sloan Kettering Cancer Center, New York, New York.; Weill Cornell Medical College, New York, New York.<br /><searchLink fieldCode="AU" term="%22Hultcrantz+M%22">Hultcrantz M</searchLink>; Department of Medicine, Myeloma Service, Memorial Sloan Kettering Cancer Center, New York, New York.; Weill Cornell Medical College, New York, New York.<br /><searchLink fieldCode="AU" term="%22Hassoun+H%22">Hassoun H</searchLink>; Department of Medicine, Myeloma Service, Memorial Sloan Kettering Cancer Center, New York, New York.; Weill Cornell Medical College, New York, New York.<br /><searchLink fieldCode="AU" term="%22Shah+GL%22">Shah GL</searchLink>; Weill Cornell Medical College, New York, New York.; Department of Medicine, Adult Bone Marrow Transplantation Service, Memorial Sloan Kettering Cancer Center, New York, New York.<br /><searchLink fieldCode="AU" term="%22Scordo+M%22">Scordo M</searchLink>; Weill Cornell Medical College, New York, New York.; Department of Medicine, Adult Bone Marrow Transplantation Service, Memorial Sloan Kettering Cancer Center, New York, New York.<br /><searchLink fieldCode="AU" term="%22Lahoud+OB%22">Lahoud OB</searchLink>; Department of Hematology and Medical Oncology, Perlmutter Cancer Center, NYU Langone Hospital, Brooklyn, New York.; Department of Medicine, NYU Grossman School of Medicine, New York, New York.<br /><searchLink fieldCode="AU" term="%22Chung+DJ%22">Chung DJ</searchLink>; Weill Cornell Medical College, New York, New York.; Department of Medicine, Adult Bone Marrow Transplantation Service, Memorial Sloan Kettering Cancer Center, New York, New York.<br /><searchLink fieldCode="AU" term="%22Landau+HJ%22">Landau HJ</searchLink>; Weill Cornell Medical College, New York, New York.; Department of Medicine, Adult Bone Marrow Transplantation Service, Memorial Sloan Kettering Cancer Center, New York, New York.<br /><searchLink fieldCode="AU" term="%22Peled+JU%22">Peled JU</searchLink>; Weill Cornell Medical College, New York, New York.; Department of Medicine, Adult Bone Marrow Transplantation Service, Memorial Sloan Kettering Cancer Center, New York, New York.<br /><searchLink fieldCode="AU" term="%22Clementi+N%22">Clementi N</searchLink>; Vita-Salute San Raffaele University , Milano, Italy.; Laboratory of Microbiology and Virology, IRCCS San Raffaele Hospital, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Chesi+M%22">Chesi M</searchLink>; Comprehensive Cancer Center, Mayo Clinic Arizona, Scottsdale, Arizona.<br /><searchLink fieldCode="AU" term="%22Bergsagel+PL%22">Bergsagel PL</searchLink>; Comprehensive Cancer Center, Mayo Clinic Arizona, Scottsdale, Arizona.<br /><searchLink fieldCode="AU" term="%22Mailankody+S%22">Mailankody S</searchLink>; Department of Medicine, Myeloma Service, Memorial Sloan Kettering Cancer Center, New York, New York.; Weill Cornell Medical College, New York, New York.<br /><searchLink fieldCode="AU" term="%22Pollak+MN%22">Pollak MN</searchLink>; Department of Medicine and Oncology, McGill University, Montreal, Canada.<br /><searchLink fieldCode="AU" term="%22D'Souza+A%22">D'Souza A</searchLink>; Medical College of Wisconsin , Milwaukee, Wisconsin.<br /><searchLink fieldCode="AU" term="%22Landgren+O%22">Landgren O</searchLink>; Division of Myeloma, Department of Medicine, Sylvester Comprehensive Cancer Center, Myeloma Division, University of Miami, Miami, Florida.<br /><searchLink fieldCode="AU" term="%22Chimonas+S%22">Chimonas S</searchLink>; Center for Health Policy and Outcomes, Memorial Sloan Kettering Cancer Center, New York, New York.<br /><searchLink fieldCode="AU" term="%22Giralt+SA%22">Giralt SA</searchLink>; Weill Cornell Medical College, New York, New York.; Department of Medicine, Adult Bone Marrow Transplantation Service, Memorial Sloan Kettering Cancer Center, New York, New York.<br /><searchLink fieldCode="AU" term="%22Usmani+SZ%22">Usmani SZ</searchLink>; Department of Medicine, Myeloma Service, Memorial Sloan Kettering Cancer Center, New York, New York.; Weill Cornell Medical College, New York, New York.<br /><searchLink fieldCode="AU" term="%22Iyengar+NM%22">Iyengar NM</searchLink>; Weill Cornell Medical College, New York, New York.; Department of Medicine, Breast Medicine Service, Memorial Sloan Kettering Cancer Center, New York, New York.<br /><searchLink fieldCode="AU" term="%22Lesokhin+AM%22">Lesokhin AM</searchLink>; Department of Medicine, Myeloma Service, Memorial Sloan Kettering Cancer Center, New York, New York.; Weill Cornell Medical College, New York, New York.<br /><searchLink fieldCode="AU" term="%22van+den+Brink+MRM%22">van den Brink MRM</searchLink>; City of Hope Los Angeles and National Medical Center, Los Angeles, California.<br /><searchLink fieldCode="AU" term="%22Bellone+M%22">Bellone M</searchLink>; Cellular Immunology Unit, Division of Immunology, Transplantation, and Infectious Diseases, IRCCS San Raffaele Scientific Institute, Milano, Italy.
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            NameFull: Hassoun H
      – PersonEntity:
          Name:
            NameFull: Shah GL
      – PersonEntity:
          Name:
            NameFull: Scordo M
      – PersonEntity:
          Name:
            NameFull: Lahoud OB
      – PersonEntity:
          Name:
            NameFull: Chung DJ
      – PersonEntity:
          Name:
            NameFull: Landau HJ
      – PersonEntity:
          Name:
            NameFull: Peled JU
      – PersonEntity:
          Name:
            NameFull: Clementi N
      – PersonEntity:
          Name:
            NameFull: Chesi M
      – PersonEntity:
          Name:
            NameFull: Bergsagel PL
      – PersonEntity:
          Name:
            NameFull: Mailankody S
      – PersonEntity:
          Name:
            NameFull: Pollak MN
      – PersonEntity:
          Name:
            NameFull: D'Souza A
      – PersonEntity:
          Name:
            NameFull: Landgren O
      – PersonEntity:
          Name:
            NameFull: Chimonas S
      – PersonEntity:
          Name:
            NameFull: Giralt SA
      – PersonEntity:
          Name:
            NameFull: Usmani SZ
      – PersonEntity:
          Name:
            NameFull: Iyengar NM
      – PersonEntity:
          Name:
            NameFull: Lesokhin AM
      – PersonEntity:
          Name:
            NameFull: van den Brink MRM
      – PersonEntity:
          Name:
            NameFull: Bellone M
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 01
              M: 04
              Text: 2026 Apr 01
              Type: published
              Y: 2026
          Identifiers:
            – Type: issn-electronic
              Value: 2159-8290
          Numbering:
            – Type: volume
              Value: 16
            – Type: issue
              Value: 4
          Titles:
            – TitleFull: Cancer discovery
              Type: main
ResultId 1