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Ultrasmall Gold Nanoparticles as "Three-in-One" Enzyme-Mimicking Nanocatalysts for Combined Sonodynamic/Catalytic Therapy in Breast Cancer.

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Title: Ultrasmall Gold Nanoparticles as "Three-in-One" Enzyme-Mimicking Nanocatalysts for Combined Sonodynamic/Catalytic Therapy in Breast Cancer.
Authors: Beishenaliev A; Department of Pharmacology, Faculty of Medicine, Universiti Malaya, 50603 Kuala Lumpur, Malaysia., Loke YL; Department of Chemistry, Faculty of Science, Universiti Malaya, 50603 Kuala Lumpur, Malaysia., Lin CY; Research Center for Radiation Medicine, Chang Gung University, 333 Taoyuan, Taiwan., Goh SJ; Department of Pharmacology, Faculty of Medicine, Universiti Malaya, 50603 Kuala Lumpur, Malaysia.; Institute of Biomedical Sciences, Academia Sinica, 11529 Taipei, Taiwan., Seema J; Institute of Biomedical Sciences, Academia Sinica, 11529 Taipei, Taiwan., Huang Y; Institute of Biomedical Sciences, Academia Sinica, 11529 Taipei, Taiwan.; College of Life Sciences, National Yang Ming Chiao Tung University, 30010 Hsinchu, Taiwan., Lim XY; Department of Pharmacology, Faculty of Medicine, Universiti Malaya, 50603 Kuala Lumpur, Malaysia., Chen YW; Biomedical Translation Research Center, Academia Sinica, 11529 Taipei, Taiwan., Leo BF; Department of Molecular Medicine, Faculty of Medicine, Universiti Malaya, 50603 Kuala Lumpur, Malaysia.; Nanotechnology and Catalysis Research Centre (NANOCAT), Institute for Advanced Studies, Universiti Malaya, 50603 Kuala Lumpur, Malaysia.; Universiti Malaya Research Centre for Biopharmaceuticals and Advanced Therapeutics, Faculty of Medicine, Universiti Malaya, 50603 Kuala Lumpur, Malaysia.; Center of Excellence for Innovative Medical Devices, University Malaya, 50603 Kuala Lumpur, Malaysia., Chang CY; Department of Biological Science and Technology, College of Engineering Bioscience, National Yang Ming Chiao Tung University, 30068 Hsinchu, Taiwan., Chung LY; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Universiti Malaya, 50603 Kuala Lumpur, Malaysia., Chang CC; Department of Biological Science and Technology, College of Engineering Bioscience, National Yang Ming Chiao Tung University, 30068 Hsinchu, Taiwan.; Center for Intelligent Drug Systems and Smart Biodevices, National Yang Ming Chiao Tung University, 30068 Hsinchu, Taiwan.; Department of Electrophysics, National Yang Ming Chiao Tung University, 30010 Hsinchu, Taiwan.; Institute of Physics, Academia Sinica, Nankang, 11529 Taipei, Taiwan.; Brain Research Center, National Tsing Hua University, 300044 Hsinchu, Taiwan., Teo YY; Department of Chemistry, Faculty of Science, Universiti Malaya, 50603 Kuala Lumpur, Malaysia., Hwang DW; Institute of Biomedical Sciences, Academia Sinica, 11529 Taipei, Taiwan.; Biomedical Translation Research Center, Academia Sinica, 11529 Taipei, Taiwan., Kiew LV; Department of Pharmacology, Faculty of Medicine, Universiti Malaya, 50603 Kuala Lumpur, Malaysia.; Universiti Malaya Research Centre for Biopharmaceuticals and Advanced Therapeutics, Faculty of Medicine, Universiti Malaya, 50603 Kuala Lumpur, Malaysia.; Center of Excellence for Innovative Medical Devices, University Malaya, 50603 Kuala Lumpur, Malaysia.; Department of Biological Science and Technology, College of Engineering Bioscience, National Yang Ming Chiao Tung University, 30068 Hsinchu, Taiwan.
Source: ACS applied materials & interfaces [ACS Appl Mater Interfaces] 2025 Dec 17; Vol. 17 (50), pp. 67529-67542. Date of Electronic Publication: 2025 Dec 04.
Publication Type: Journal Article
Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101504991 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1944-8252 (Electronic) Linking ISSN: 19448244 NLM ISO Abbreviation: ACS Appl Mater Interfaces Subsets: MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22Beishenaliev+A%22">Beishenaliev A</searchLink>; Department of Pharmacology, Faculty of Medicine, Universiti Malaya, 50603 Kuala Lumpur, Malaysia.<br /><searchLink fieldCode="AU" term="%22Loke+YL%22">Loke YL</searchLink>; Department of Chemistry, Faculty of Science, Universiti Malaya, 50603 Kuala Lumpur, Malaysia.<br /><searchLink fieldCode="AU" term="%22Lin+CY%22">Lin CY</searchLink>; Research Center for Radiation Medicine, Chang Gung University, 333 Taoyuan, Taiwan.<br /><searchLink fieldCode="AU" term="%22Goh+SJ%22">Goh SJ</searchLink>; Department of Pharmacology, Faculty of Medicine, Universiti Malaya, 50603 Kuala Lumpur, Malaysia.; Institute of Biomedical Sciences, Academia Sinica, 11529 Taipei, Taiwan.<br /><searchLink fieldCode="AU" term="%22Seema+J%22">Seema J</searchLink>; Institute of Biomedical Sciences, Academia Sinica, 11529 Taipei, Taiwan.<br /><searchLink fieldCode="AU" term="%22Huang+Y%22">Huang Y</searchLink>; Institute of Biomedical Sciences, Academia Sinica, 11529 Taipei, Taiwan.; College of Life Sciences, National Yang Ming Chiao Tung University, 30010 Hsinchu, Taiwan.<br /><searchLink fieldCode="AU" term="%22Lim+XY%22">Lim XY</searchLink>; Department of Pharmacology, Faculty of Medicine, Universiti Malaya, 50603 Kuala Lumpur, Malaysia.<br /><searchLink fieldCode="AU" term="%22Chen+YW%22">Chen YW</searchLink>; Biomedical Translation Research Center, Academia Sinica, 11529 Taipei, Taiwan.<br /><searchLink fieldCode="AU" term="%22Leo+BF%22">Leo BF</searchLink>; Department of Molecular Medicine, Faculty of Medicine, Universiti Malaya, 50603 Kuala Lumpur, Malaysia.; Nanotechnology and Catalysis Research Centre (NANOCAT), Institute for Advanced Studies, Universiti Malaya, 50603 Kuala Lumpur, Malaysia.; Universiti Malaya Research Centre for Biopharmaceuticals and Advanced Therapeutics, Faculty of Medicine, Universiti Malaya, 50603 Kuala Lumpur, Malaysia.; Center of Excellence for Innovative Medical Devices, University Malaya, 50603 Kuala Lumpur, Malaysia.<br /><searchLink fieldCode="AU" term="%22Chang+CY%22">Chang CY</searchLink>; Department of Biological Science and Technology, College of Engineering Bioscience, National Yang Ming Chiao Tung University, 30068 Hsinchu, Taiwan.<br /><searchLink fieldCode="AU" term="%22Chung+LY%22">Chung LY</searchLink>; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Universiti Malaya, 50603 Kuala Lumpur, Malaysia.<br /><searchLink fieldCode="AU" term="%22Chang+CC%22">Chang CC</searchLink>; Department of Biological Science and Technology, College of Engineering Bioscience, National Yang Ming Chiao Tung University, 30068 Hsinchu, Taiwan.; Center for Intelligent Drug Systems and Smart Biodevices, National Yang Ming Chiao Tung University, 30068 Hsinchu, Taiwan.; Department of Electrophysics, National Yang Ming Chiao Tung University, 30010 Hsinchu, Taiwan.; Institute of Physics, Academia Sinica, Nankang, 11529 Taipei, Taiwan.; Brain Research Center, National Tsing Hua University, 300044 Hsinchu, Taiwan.<br /><searchLink fieldCode="AU" term="%22Teo+YY%22">Teo YY</searchLink>; Department of Chemistry, Faculty of Science, Universiti Malaya, 50603 Kuala Lumpur, Malaysia.<br /><searchLink fieldCode="AU" term="%22Hwang+DW%22">Hwang DW</searchLink>; Institute of Biomedical Sciences, Academia Sinica, 11529 Taipei, Taiwan.; Biomedical Translation Research Center, Academia Sinica, 11529 Taipei, Taiwan.<br /><searchLink fieldCode="AU" term="%22Kiew+LV%22">Kiew LV</searchLink>; Department of Pharmacology, Faculty of Medicine, Universiti Malaya, 50603 Kuala Lumpur, Malaysia.; Universiti Malaya Research Centre for Biopharmaceuticals and Advanced Therapeutics, Faculty of Medicine, Universiti Malaya, 50603 Kuala Lumpur, Malaysia.; Center of Excellence for Innovative Medical Devices, University Malaya, 50603 Kuala Lumpur, Malaysia.; Department of Biological Science and Technology, College of Engineering Bioscience, National Yang Ming Chiao Tung University, 30068 Hsinchu, Taiwan.
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        Value: 10.1021/acsami.5c15866
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              Text: 2025 Dec 17
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