Secreted frizzled-related protein 2 monoclonal antibody-mediated IFN-ϒ reprograms tumor-associated macrophages to suppress triple negative breast cancer.
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| Title: | Secreted frizzled-related protein 2 monoclonal antibody-mediated IFN-ϒ reprograms tumor-associated macrophages to suppress triple negative breast cancer. |
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| Authors: | Hsu L; Department of Surgery, Hollings Cancer Center, Medical University of South Carolina, 86 Jonathan Lucas St, HO712J, Charleston, SC, 29425, USA., Siegel J; Department of Surgery, Hollings Cancer Center, Medical University of South Carolina, 86 Jonathan Lucas St, HO712J, Charleston, SC, 29425, USA., Nasarre P; Therapeutics Biochemistry and Molecular Biology, Medical University of South Carolina, Charleston, SC, 29425, USA., Oberholtzer N; Department of Surgery, Hollings Cancer Center, Medical University of South Carolina, 86 Jonathan Lucas St, HO712J, Charleston, SC, 29425, USA., Mukherjee R; Department of Surgery, Hollings Cancer Center, Medical University of South Carolina, 86 Jonathan Lucas St, HO712J, Charleston, SC, 29425, USA., Hilliard E; Department of Surgery, Hollings Cancer Center, Medical University of South Carolina, 86 Jonathan Lucas St, HO712J, Charleston, SC, 29425, USA., Chakraborty P; Department of Surgery, Hollings Cancer Center, Medical University of South Carolina, 86 Jonathan Lucas St, HO712J, Charleston, SC, 29425, USA., Burge RA; Therapeutics Biochemistry and Molecular Biology, Medical University of South Carolina, Charleston, SC, 29425, USA., O'Quinn EC; Hollings Cancer Center Biorepository and Tissue Analysis Shared Resource, Medical University of South Carolina, Charleston, SC, 29425, USA., Sweatt O; Department of Surgery, Hollings Cancer Center, Medical University of South Carolina, 86 Jonathan Lucas St, HO712J, Charleston, SC, 29425, USA., Kassir MF; Therapeutics Biochemistry and Molecular Biology, Medical University of South Carolina, Charleston, SC, 29425, USA., Hobbs GA; Therapeutics Biochemistry and Molecular Biology, Medical University of South Carolina, Charleston, SC, 29425, USA., Ostrowski M; Therapeutics Biochemistry and Molecular Biology, Medical University of South Carolina, Charleston, SC, 29425, USA., Broome AM; Therapeutics Biochemistry and Molecular Biology, Medical University of South Carolina, Charleston, SC, 29425, USA., Mehrotra S; Department of Surgery, Hollings Cancer Center, Medical University of South Carolina, 86 Jonathan Lucas St, HO712J, Charleston, SC, 29425, USA., Klauber-DeMore N; Department of Surgery, Hollings Cancer Center, Medical University of South Carolina, 86 Jonathan Lucas St, HO712J, Charleston, SC, 29425, USA. demore@musc.edu. |
| Source: | Breast cancer research : BCR [Breast Cancer Res] 2025 Dec 05; Vol. 27 (1), pp. 209. Date of Electronic Publication: 2025 Dec 05. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: BioMed Central Ltd Country of Publication: England NLM ID: 100927353 Publication Model: Electronic Cited Medium: Internet ISSN: 1465-542X (Electronic) Linking ISSN: 14655411 NLM ISO Abbreviation: Breast Cancer Res Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 41345673 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Secreted frizzled-related protein 2 monoclonal antibody-mediated IFN-ϒ reprograms tumor-associated macrophages to suppress triple negative breast cancer. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Hsu+L%22">Hsu L</searchLink>; Department of Surgery, Hollings Cancer Center, Medical University of South Carolina, 86 Jonathan Lucas St, HO712J, Charleston, SC, 29425, USA.<br /><searchLink fieldCode="AU" term="%22Siegel+J%22">Siegel J</searchLink>; Department of Surgery, Hollings Cancer Center, Medical University of South Carolina, 86 Jonathan Lucas St, HO712J, Charleston, SC, 29425, USA.<br /><searchLink fieldCode="AU" term="%22Nasarre+P%22">Nasarre P</searchLink>; Therapeutics Biochemistry and Molecular Biology, Medical University of South Carolina, Charleston, SC, 29425, USA.<br /><searchLink fieldCode="AU" term="%22Oberholtzer+N%22">Oberholtzer N</searchLink>; Department of Surgery, Hollings Cancer Center, Medical University of South Carolina, 86 Jonathan Lucas St, HO712J, Charleston, SC, 29425, USA.<br /><searchLink fieldCode="AU" term="%22Mukherjee+R%22">Mukherjee R</searchLink>; Department of Surgery, Hollings Cancer Center, Medical University of South Carolina, 86 Jonathan Lucas St, HO712J, Charleston, SC, 29425, USA.<br /><searchLink fieldCode="AU" term="%22Hilliard+E%22">Hilliard E</searchLink>; Department of Surgery, Hollings Cancer Center, Medical University of South Carolina, 86 Jonathan Lucas St, HO712J, Charleston, SC, 29425, USA.<br /><searchLink fieldCode="AU" term="%22Chakraborty+P%22">Chakraborty P</searchLink>; Department of Surgery, Hollings Cancer Center, Medical University of South Carolina, 86 Jonathan Lucas St, HO712J, Charleston, SC, 29425, USA.<br /><searchLink fieldCode="AU" term="%22Burge+RA%22">Burge RA</searchLink>; Therapeutics Biochemistry and Molecular Biology, Medical University of South Carolina, Charleston, SC, 29425, USA.<br /><searchLink fieldCode="AU" term="%22O'Quinn+EC%22">O'Quinn EC</searchLink>; Hollings Cancer Center Biorepository and Tissue Analysis Shared Resource, Medical University of South Carolina, Charleston, SC, 29425, USA.<br /><searchLink fieldCode="AU" term="%22Sweatt+O%22">Sweatt O</searchLink>; Department of Surgery, Hollings Cancer Center, Medical University of South Carolina, 86 Jonathan Lucas St, HO712J, Charleston, SC, 29425, USA.<br /><searchLink fieldCode="AU" term="%22Kassir+MF%22">Kassir MF</searchLink>; Therapeutics Biochemistry and Molecular Biology, Medical University of South Carolina, Charleston, SC, 29425, USA.<br /><searchLink fieldCode="AU" term="%22Hobbs+GA%22">Hobbs GA</searchLink>; Therapeutics Biochemistry and Molecular Biology, Medical University of South Carolina, Charleston, SC, 29425, USA.<br /><searchLink fieldCode="AU" term="%22Ostrowski+M%22">Ostrowski M</searchLink>; Therapeutics Biochemistry and Molecular Biology, Medical University of South Carolina, Charleston, SC, 29425, USA.<br /><searchLink fieldCode="AU" term="%22Broome+AM%22">Broome AM</searchLink>; Therapeutics Biochemistry and Molecular Biology, Medical University of South Carolina, Charleston, SC, 29425, USA.<br /><searchLink fieldCode="AU" term="%22Mehrotra+S%22">Mehrotra S</searchLink>; Department of Surgery, Hollings Cancer Center, Medical University of South Carolina, 86 Jonathan Lucas St, HO712J, Charleston, SC, 29425, USA.<br /><searchLink fieldCode="AU" term="%22Klauber-DeMore+N%22">Klauber-DeMore N</searchLink>; Department of Surgery, Hollings Cancer Center, Medical University of South Carolina, 86 Jonathan Lucas St, HO712J, Charleston, SC, 29425, USA. demore@musc.edu. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22100927353%22">Breast cancer research : BCR</searchLink> [Breast Cancer Res] 2025 Dec 05; Vol. 27 (1), pp. 209. <i>Date of Electronic Publication: </i>2025 Dec 05. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22BioMed+Central+Ltd%22">BioMed Central Ltd </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>100927353 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1465-542X (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2214655411%22">14655411 </searchLink><i>NLM ISO Abbreviation: </i>Breast Cancer Res <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=41345673 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1186/s13058-025-02176-6 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 209 Titles: – TitleFull: Secreted frizzled-related protein 2 monoclonal antibody-mediated IFN-ϒ reprograms tumor-associated macrophages to suppress triple negative breast cancer. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Hsu L – PersonEntity: Name: NameFull: Siegel J – PersonEntity: Name: NameFull: Nasarre P – PersonEntity: Name: NameFull: Oberholtzer N – PersonEntity: Name: NameFull: Mukherjee R – PersonEntity: Name: NameFull: Hilliard E – PersonEntity: Name: NameFull: Chakraborty P – PersonEntity: Name: NameFull: Burge RA – PersonEntity: Name: NameFull: O'Quinn EC – PersonEntity: Name: NameFull: Sweatt O – PersonEntity: Name: NameFull: Kassir MF – PersonEntity: Name: NameFull: Hobbs GA – PersonEntity: Name: NameFull: Ostrowski M – PersonEntity: Name: NameFull: Broome AM – PersonEntity: Name: NameFull: Mehrotra S – PersonEntity: Name: NameFull: Klauber-DeMore N IsPartOfRelationships: – BibEntity: Dates: – D: 05 M: 12 Text: 2025 Dec 05 Type: published Y: 2025 Identifiers: – Type: issn-electronic Value: 1465-542X Numbering: – Type: volume Value: 27 – Type: issue Value: 1 Titles: – TitleFull: Breast cancer research : BCR Type: main |
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