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Secreted frizzled-related protein 2 monoclonal antibody-mediated IFN-ϒ reprograms tumor-associated macrophages to suppress triple negative breast cancer.

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Bibliographic Details
Title: Secreted frizzled-related protein 2 monoclonal antibody-mediated IFN-ϒ reprograms tumor-associated macrophages to suppress triple negative breast cancer.
Authors: Hsu L; Department of Surgery, Hollings Cancer Center, Medical University of South Carolina, 86 Jonathan Lucas St, HO712J, Charleston, SC, 29425, USA., Siegel J; Department of Surgery, Hollings Cancer Center, Medical University of South Carolina, 86 Jonathan Lucas St, HO712J, Charleston, SC, 29425, USA., Nasarre P; Therapeutics Biochemistry and Molecular Biology, Medical University of South Carolina, Charleston, SC, 29425, USA., Oberholtzer N; Department of Surgery, Hollings Cancer Center, Medical University of South Carolina, 86 Jonathan Lucas St, HO712J, Charleston, SC, 29425, USA., Mukherjee R; Department of Surgery, Hollings Cancer Center, Medical University of South Carolina, 86 Jonathan Lucas St, HO712J, Charleston, SC, 29425, USA., Hilliard E; Department of Surgery, Hollings Cancer Center, Medical University of South Carolina, 86 Jonathan Lucas St, HO712J, Charleston, SC, 29425, USA., Chakraborty P; Department of Surgery, Hollings Cancer Center, Medical University of South Carolina, 86 Jonathan Lucas St, HO712J, Charleston, SC, 29425, USA., Burge RA; Therapeutics Biochemistry and Molecular Biology, Medical University of South Carolina, Charleston, SC, 29425, USA., O'Quinn EC; Hollings Cancer Center Biorepository and Tissue Analysis Shared Resource, Medical University of South Carolina, Charleston, SC, 29425, USA., Sweatt O; Department of Surgery, Hollings Cancer Center, Medical University of South Carolina, 86 Jonathan Lucas St, HO712J, Charleston, SC, 29425, USA., Kassir MF; Therapeutics Biochemistry and Molecular Biology, Medical University of South Carolina, Charleston, SC, 29425, USA., Hobbs GA; Therapeutics Biochemistry and Molecular Biology, Medical University of South Carolina, Charleston, SC, 29425, USA., Ostrowski M; Therapeutics Biochemistry and Molecular Biology, Medical University of South Carolina, Charleston, SC, 29425, USA., Broome AM; Therapeutics Biochemistry and Molecular Biology, Medical University of South Carolina, Charleston, SC, 29425, USA., Mehrotra S; Department of Surgery, Hollings Cancer Center, Medical University of South Carolina, 86 Jonathan Lucas St, HO712J, Charleston, SC, 29425, USA., Klauber-DeMore N; Department of Surgery, Hollings Cancer Center, Medical University of South Carolina, 86 Jonathan Lucas St, HO712J, Charleston, SC, 29425, USA. demore@musc.edu.
Source: Breast cancer research : BCR [Breast Cancer Res] 2025 Dec 05; Vol. 27 (1), pp. 209. Date of Electronic Publication: 2025 Dec 05.
Publication Type: Journal Article
Journal Info: Publisher: BioMed Central Ltd Country of Publication: England NLM ID: 100927353 Publication Model: Electronic Cited Medium: Internet ISSN: 1465-542X (Electronic) Linking ISSN: 14655411 NLM ISO Abbreviation: Breast Cancer Res Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1465-542X
DOI:10.1186/s13058-025-02176-6