CldU sensitizes BRCA2 reverse-mutated cells to PARP inhibitors.

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Title: CldU sensitizes BRCA2 reverse-mutated cells to PARP inhibitors.
Authors: Zouggari N; Department of Medicine and Center of Translational Research in Onco-Hematology, Faculty of Medicine, University of Geneva, Geneva, Switzerland.; Department of Molecular and Cellular Biology, Faculty of Sciences, University of Geneva, Geneva, Switzerland., Trugenberger C; Department of Medicine and Center of Translational Research in Onco-Hematology, Faculty of Medicine, University of Geneva, Geneva, Switzerland.; Department of Molecular and Cellular Biology, Faculty of Sciences, University of Geneva, Geneva, Switzerland., Du Bois V; Department of Medicine and Center of Translational Research in Onco-Hematology, Faculty of Medicine, University of Geneva, Geneva, Switzerland., Wang W; Department of Medicine and Center of Translational Research in Onco-Hematology, Faculty of Medicine, University of Geneva, Geneva, Switzerland., Rossetti GG; Department of Molecular and Cellular Biology, Faculty of Sciences, University of Geneva, Geneva, Switzerland., Halazonetis TD; Department of Molecular and Cellular Biology, Faculty of Sciences, University of Geneva, Geneva, Switzerland., Labidi-Galy I; Department of Medicine and Center of Translational Research in Onco-Hematology, Faculty of Medicine, University of Geneva, Geneva, Switzerland.; Department of Oncology, Geneva University Hospitals, Geneva, Switzerland.
Source: Frontiers in oncology [Front Oncol] 2025 Nov 19; Vol. 15, pp. 1626301. Date of Electronic Publication: 2025 Nov 19 (Print Publication: 2025).
Publication Type: Journal Article
Journal Info: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101568867 Publication Model: eCollection Cited Medium: Print ISSN: 2234-943X (Print) Linking ISSN: 2234943X NLM ISO Abbreviation: Front Oncol Subsets: PubMed not MEDLINE
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  Data: CldU sensitizes BRCA2 reverse-mutated cells to PARP inhibitors.
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  Data: <searchLink fieldCode="AU" term="%22Zouggari+N%22">Zouggari N</searchLink>; Department of Medicine and Center of Translational Research in Onco-Hematology, Faculty of Medicine, University of Geneva, Geneva, Switzerland.; Department of Molecular and Cellular Biology, Faculty of Sciences, University of Geneva, Geneva, Switzerland.<br /><searchLink fieldCode="AU" term="%22Trugenberger+C%22">Trugenberger C</searchLink>; Department of Medicine and Center of Translational Research in Onco-Hematology, Faculty of Medicine, University of Geneva, Geneva, Switzerland.; Department of Molecular and Cellular Biology, Faculty of Sciences, University of Geneva, Geneva, Switzerland.<br /><searchLink fieldCode="AU" term="%22Du+Bois+V%22">Du Bois V</searchLink>; Department of Medicine and Center of Translational Research in Onco-Hematology, Faculty of Medicine, University of Geneva, Geneva, Switzerland.<br /><searchLink fieldCode="AU" term="%22Wang+W%22">Wang W</searchLink>; Department of Medicine and Center of Translational Research in Onco-Hematology, Faculty of Medicine, University of Geneva, Geneva, Switzerland.<br /><searchLink fieldCode="AU" term="%22Rossetti+GG%22">Rossetti GG</searchLink>; Department of Molecular and Cellular Biology, Faculty of Sciences, University of Geneva, Geneva, Switzerland.<br /><searchLink fieldCode="AU" term="%22Halazonetis+TD%22">Halazonetis TD</searchLink>; Department of Molecular and Cellular Biology, Faculty of Sciences, University of Geneva, Geneva, Switzerland.<br /><searchLink fieldCode="AU" term="%22Labidi-Galy+I%22">Labidi-Galy I</searchLink>; Department of Medicine and Center of Translational Research in Onco-Hematology, Faculty of Medicine, University of Geneva, Geneva, Switzerland.; Department of Oncology, Geneva University Hospitals, Geneva, Switzerland.
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        Value: 10.3389/fonc.2025.1626301
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              Text: 2025 Nov 19
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