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Filgotinib Is an Effective and Safe Treatment Option for Difficult-To-Treat Ulcerative Colitis: Real-World Evidence of the Dutch Initiative on Crohn and Colitis (ICC) Registry.

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Title: Filgotinib Is an Effective and Safe Treatment Option for Difficult-To-Treat Ulcerative Colitis: Real-World Evidence of the Dutch Initiative on Crohn and Colitis (ICC) Registry.
Authors: Naber MR; Department of Gastroenterology and Hepatology, University Medical Centre Utrecht, Utrecht, the Netherlands.; Department of Gastroenterology and Hepatology, Amsterdam Gastroenterology Endocrinology Metabolism (AGEM) Research Institute, Amsterdam UMC, Amsterdam, the Netherlands., van der Meulen AE; Department of Gastroenterology and Hepatology, Leiden University Medical Centre, Leiden, the Netherlands., Voorneveld PW; Department of Gastroenterology and Hepatology, Leiden University Medical Centre, Leiden, the Netherlands., Veltkamp SHC; Department of Gastroenterology and Hepatology, Leiden University Medical Centre, Leiden, the Netherlands., van Bodegraven AA; Department of Gastroenterology and Hepatology, Zuyderland Hospital, Sittard, the Netherlands., Bodelier A; Amphia Hospital, Breda, the Netherlands., Mujagic Z; Maastricht University Medical Centre, Maastricht, the Netherlands., Pierik M; Maastricht University Medical Centre, Maastricht, the Netherlands., Verleye LMM; Maastricht University Medical Centre, Maastricht, the Netherlands.; Radboud University Medical Centre, Nijmegen, the Netherlands., Duijvestein M; Radboud University Medical Centre, Nijmegen, the Netherlands., Bouwknegt DG; University Medical Centre Groningen, Groningen, the Netherlands., Visschedijk MC; University Medical Centre Groningen, Groningen, the Netherlands., Srivastava N; Haaglanden Medical Centre, The Hague, the Netherlands., West RL; Franciscus Hospital, Rotterdam, the Netherlands., Oldenburg B; Department of Gastroenterology and Hepatology, University Medical Centre Utrecht, Utrecht, the Netherlands., Löwenberg M; University Medical Centre Groningen, Groningen, the Netherlands., van Schaik FDM; Department of Gastroenterology and Hepatology, University Medical Centre Utrecht, Utrecht, the Netherlands.
Corporate Authors: Dutch ICC Registry
Source: United European gastroenterology journal [United European Gastroenterol J] 2026 Feb; Vol. 14 (1), pp. e70141. Date of Electronic Publication: 2025 Dec 05.
Publication Type: Journal Article; Multicenter Study
Journal Info: Publisher: Wiley Country of Publication: England NLM ID: 101606807 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2050-6414 (Electronic) Linking ISSN: 20506406 NLM ISO Abbreviation: United European Gastroenterol J Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Filgotinib Is an Effective and Safe Treatment Option for Difficult-To-Treat Ulcerative Colitis: Real-World Evidence of the Dutch Initiative on Crohn and Colitis (ICC) Registry.
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  Data: <searchLink fieldCode="AU" term="%22Naber+MR%22">Naber MR</searchLink>; Department of Gastroenterology and Hepatology, University Medical Centre Utrecht, Utrecht, the Netherlands.; Department of Gastroenterology and Hepatology, Amsterdam Gastroenterology Endocrinology Metabolism (AGEM) Research Institute, Amsterdam UMC, Amsterdam, the Netherlands.<br /><searchLink fieldCode="AU" term="%22van+der+Meulen+AE%22">van der Meulen AE</searchLink>; Department of Gastroenterology and Hepatology, Leiden University Medical Centre, Leiden, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Voorneveld+PW%22">Voorneveld PW</searchLink>; Department of Gastroenterology and Hepatology, Leiden University Medical Centre, Leiden, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Veltkamp+SHC%22">Veltkamp SHC</searchLink>; Department of Gastroenterology and Hepatology, Leiden University Medical Centre, Leiden, the Netherlands.<br /><searchLink fieldCode="AU" term="%22van+Bodegraven+AA%22">van Bodegraven AA</searchLink>; Department of Gastroenterology and Hepatology, Zuyderland Hospital, Sittard, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Bodelier+A%22">Bodelier A</searchLink>; Amphia Hospital, Breda, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Mujagic+Z%22">Mujagic Z</searchLink>; Maastricht University Medical Centre, Maastricht, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Pierik+M%22">Pierik M</searchLink>; Maastricht University Medical Centre, Maastricht, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Verleye+LMM%22">Verleye LMM</searchLink>; Maastricht University Medical Centre, Maastricht, the Netherlands.; Radboud University Medical Centre, Nijmegen, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Duijvestein+M%22">Duijvestein M</searchLink>; Radboud University Medical Centre, Nijmegen, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Bouwknegt+DG%22">Bouwknegt DG</searchLink>; University Medical Centre Groningen, Groningen, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Visschedijk+MC%22">Visschedijk MC</searchLink>; University Medical Centre Groningen, Groningen, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Srivastava+N%22">Srivastava N</searchLink>; Haaglanden Medical Centre, The Hague, the Netherlands.<br /><searchLink fieldCode="AU" term="%22West+RL%22">West RL</searchLink>; Franciscus Hospital, Rotterdam, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Oldenburg+B%22">Oldenburg B</searchLink>; Department of Gastroenterology and Hepatology, University Medical Centre Utrecht, Utrecht, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Löwenberg+M%22">Löwenberg M</searchLink>; University Medical Centre Groningen, Groningen, the Netherlands.<br /><searchLink fieldCode="AU" term="%22van+Schaik+FDM%22">van Schaik FDM</searchLink>; Department of Gastroenterology and Hepatology, University Medical Centre Utrecht, Utrecht, the Netherlands.
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