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Complexity of Adherence Challenges: Understanding Syndemic Factors Affecting HIV Treatment Adherence During Treatment Initiation in Cape Town, South Africa.

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Title: Complexity of Adherence Challenges: Understanding Syndemic Factors Affecting HIV Treatment Adherence During Treatment Initiation in Cape Town, South Africa.
Authors: Kaiser JL; Department of Global Health, Boston University School of Public Health, Boston, MA, USA. jlkaiser@bu.edu., Trowbridge E; Department of Global Health, Boston University School of Public Health, Boston, MA, USA., Vian T; Lone Mountain Global LLP, Newton, MA, USA.; WHO Collaborating Centre for Governance, Accountability, and Transparency inthe Pharmaceutical Sector, Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, ON, Canada., Haberer JE; Center for Global Health, Massachusetts General Hospital, MA, Boston, USA.; Department of Medicine, Harvard Medical School, Boston, MA, USA., Paudel R; Department of Global Health, Boston University School of Public Health, Boston, MA, USA., DeMaria J; Department of Global Health, Boston University School of Public Health, Boston, MA, USA., Orrell C; Desmond Tutu HIV Centre, Institute of Infectious Diseases and Molecular Medicine and the Department of Medicine, University of Cape Town, Cape Town, South Africa.; HIV and other Infectious Diseases Research Unit, South African Medical Research Council, Cape Town, South Africa., Jennings L; Desmond Tutu Health Foundation, Institute of Infectious Diseases and Molecular Medicine and the Department of Medicine, University of Cape Town, Cape Town, South Africa., Gifford AL; Section of General Internal Medicine, Boston University Chobanian & Avedisian School of Medicine, Boston, MA, USA.; Department of Health Law, Policy and Management, Boston University School of Public Health, Boston, MA, USA.; Center for Healthcare Organization and Implementation Research, VA Boston Healthcare System, Boston, MA, USA., Halim N; Department of Global Health, Boston University School of Public Health, Boston, MA, USA., Berkowitz N; City of Cape Town Health Department, Cape Town, South Africa., MacLeod WB; Department of Global Health, Boston University School of Public Health, Boston, MA, USA.; Health Economics and Epidemiology Research Office, Department of Internal Medicine, School of Clinical Medicine, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa., Sabin LL; Department of Global Health, Boston University School of Public Health, Boston, MA, USA.
Source: AIDS and behavior [AIDS Behav] 2026 May; Vol. 30 (5), pp. 1418-1438. Date of Electronic Publication: 2025 Dec 05.
Publication Type: Journal Article
Journal Info: Publisher: Springer Science + Business Media Country of Publication: United States NLM ID: 9712133 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1573-3254 (Electronic) Linking ISSN: 10907165 NLM ISO Abbreviation: AIDS Behav Subsets: MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22Kaiser+JL%22">Kaiser JL</searchLink>; Department of Global Health, Boston University School of Public Health, Boston, MA, USA. jlkaiser@bu.edu.<br /><searchLink fieldCode="AU" term="%22Trowbridge+E%22">Trowbridge E</searchLink>; Department of Global Health, Boston University School of Public Health, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Vian+T%22">Vian T</searchLink>; Lone Mountain Global LLP, Newton, MA, USA.; WHO Collaborating Centre for Governance, Accountability, and Transparency inthe Pharmaceutical Sector, Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Haberer+JE%22">Haberer JE</searchLink>; Center for Global Health, Massachusetts General Hospital, MA, Boston, USA.; Department of Medicine, Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Paudel+R%22">Paudel R</searchLink>; Department of Global Health, Boston University School of Public Health, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22DeMaria+J%22">DeMaria J</searchLink>; Department of Global Health, Boston University School of Public Health, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Orrell+C%22">Orrell C</searchLink>; Desmond Tutu HIV Centre, Institute of Infectious Diseases and Molecular Medicine and the Department of Medicine, University of Cape Town, Cape Town, South Africa.; HIV and other Infectious Diseases Research Unit, South African Medical Research Council, Cape Town, South Africa.<br /><searchLink fieldCode="AU" term="%22Jennings+L%22">Jennings L</searchLink>; Desmond Tutu Health Foundation, Institute of Infectious Diseases and Molecular Medicine and the Department of Medicine, University of Cape Town, Cape Town, South Africa.<br /><searchLink fieldCode="AU" term="%22Gifford+AL%22">Gifford AL</searchLink>; Section of General Internal Medicine, Boston University Chobanian & Avedisian School of Medicine, Boston, MA, USA.; Department of Health Law, Policy and Management, Boston University School of Public Health, Boston, MA, USA.; Center for Healthcare Organization and Implementation Research, VA Boston Healthcare System, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Halim+N%22">Halim N</searchLink>; Department of Global Health, Boston University School of Public Health, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Berkowitz+N%22">Berkowitz N</searchLink>; City of Cape Town Health Department, Cape Town, South Africa.<br /><searchLink fieldCode="AU" term="%22MacLeod+WB%22">MacLeod WB</searchLink>; Department of Global Health, Boston University School of Public Health, Boston, MA, USA.; Health Economics and Epidemiology Research Office, Department of Internal Medicine, School of Clinical Medicine, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.<br /><searchLink fieldCode="AU" term="%22Sabin+LL%22">Sabin LL</searchLink>; Department of Global Health, Boston University School of Public Health, Boston, MA, USA.
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