Iron-catalyzed three-component amino(radio)fluorination of alkenes to unprotected β-(radio)fluoroamines.
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| Title: | Iron-catalyzed three-component amino(radio)fluorination of alkenes to unprotected β-(radio)fluoroamines. |
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| Authors: | Li Y; National Engineering Laboratory for Druggable Gene and Protein Screening, College of Life Science, Northeast Normal University, Changchun, China.; Department of Chemistry, Jilin Province Key Laboratory of Organic Functional Molecular Design & Synthesis, Northeast Normal University, Changchun, China., Zhou Y; Warshel Institute for Computational Biology, School of Medicine, The Chinese University of Hong Kong, Shenzhen, Shenzhen, China., Bortolus MR; Azrieli Centre for Neuro-Radiochemistry, Brain Health Imaging Centre, Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health (CAMH), Toronto, ON, Canada.; Department of Chemistry, Pharmacology and Toxicology, and/or Psychiatry, University of Toronto, Toronto, ON, Canada., Zhang X; Department of Chemistry, Jilin Province Key Laboratory of Organic Functional Molecular Design & Synthesis, Northeast Normal University, Changchun, China., Wang Z; Department of Chemistry, Jilin Province Key Laboratory of Organic Functional Molecular Design & Synthesis, Northeast Normal University, Changchun, China., Liu D; Department of Chemistry, Jilin Province Key Laboratory of Organic Functional Molecular Design & Synthesis, Northeast Normal University, Changchun, China., Le H; Azrieli Centre for Neuro-Radiochemistry, Brain Health Imaging Centre, Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health (CAMH), Toronto, ON, Canada.; Department of Chemistry, Pharmacology and Toxicology, and/or Psychiatry, University of Toronto, Toronto, ON, Canada., Esezobor OZ; Azrieli Centre for Neuro-Radiochemistry, Brain Health Imaging Centre, Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health (CAMH), Toronto, ON, Canada., Ni J; Warshel Institute for Computational Biology, School of Medicine, The Chinese University of Hong Kong, Shenzhen, Shenzhen, China., Zhang Q; Department of Chemistry, Jilin Province Key Laboratory of Organic Functional Molecular Design & Synthesis, Northeast Normal University, Changchun, China., Vasdev N; Azrieli Centre for Neuro-Radiochemistry, Brain Health Imaging Centre, Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health (CAMH), Toronto, ON, Canada.; Department of Chemistry, Pharmacology and Toxicology, and/or Psychiatry, University of Toronto, Toronto, ON, Canada., Cheng GJ; Warshel Institute for Computational Biology, School of Medicine, The Chinese University of Hong Kong, Shenzhen, Shenzhen, China. chengguijuan@cuhk.edu.cn., Zheng C; Azrieli Centre for Neuro-Radiochemistry, Brain Health Imaging Centre, Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health (CAMH), Toronto, ON, Canada. chao.zheng@camh.ca.; Department of Chemistry, Pharmacology and Toxicology, and/or Psychiatry, University of Toronto, Toronto, ON, Canada. chao.zheng@camh.ca., Fu J; National Engineering Laboratory for Druggable Gene and Protein Screening, College of Life Science, Northeast Normal University, Changchun, China. fujk109@nenu.edu.cn.; Department of Chemistry, Jilin Province Key Laboratory of Organic Functional Molecular Design & Synthesis, Northeast Normal University, Changchun, China. fujk109@nenu.edu.cn. |
| Source: | Nature communications [Nat Commun] 2025 Dec 05; Vol. 16 (1), pp. 10917. Date of Electronic Publication: 2025 Dec 05. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2041-1723 |
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| DOI: | 10.1038/s41467-025-65880-z |
