VIRGO2: an enhanced gene catalog of the vaginal microbiome provides insights into its functional and ecology complexity.

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Title: VIRGO2: an enhanced gene catalog of the vaginal microbiome provides insights into its functional and ecology complexity.
Authors: France MT; Center for Advanced Microbiome Research and Innovation, Institute for Genome Sciences, University of Maryland School of Medicine, Baltimore, MD, USA.; Department of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, MD, USA., Chaudry I; Center for Advanced Microbiome Research and Innovation, Institute for Genome Sciences, University of Maryland School of Medicine, Baltimore, MD, USA.; Department of Biochemistry and Molecular Biology, University of Maryland School of Medicine, Baltimore, MD, USA., Rutt L; Center for Advanced Microbiome Research and Innovation, Institute for Genome Sciences, University of Maryland School of Medicine, Baltimore, MD, USA.; Department of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, MD, USA., Quain M; Center for Advanced Microbiome Research and Innovation, Institute for Genome Sciences, University of Maryland School of Medicine, Baltimore, MD, USA.; Department of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, MD, USA., Shirtliff B; Center for Advanced Microbiome Research and Innovation, Institute for Genome Sciences, University of Maryland School of Medicine, Baltimore, MD, USA.; Department of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, MD, USA., McComb E; Center for Advanced Microbiome Research and Innovation, Institute for Genome Sciences, University of Maryland School of Medicine, Baltimore, MD, USA.; Department of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, MD, USA., Maros A; Center for Advanced Microbiome Research and Innovation, Institute for Genome Sciences, University of Maryland School of Medicine, Baltimore, MD, USA.; Department of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, MD, USA., Alizadeh M; Center for Advanced Microbiome Research and Innovation, Institute for Genome Sciences, University of Maryland School of Medicine, Baltimore, MD, USA., Hussain FA; Department of Biology, School of Arts and Sciences, Tufts University, Medford, MA, USA., Elovitz MA; Women's Biomedical Research Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Department of Obstetrics, Gynecology and Reproductive Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Relman DA; Department of Medicine, Stanford University School of Medicine, Stanford, CA, USA.; Department of Microbiology & Immunology, Stanford University School of Medicine, Stanford, CA, USA.; Infectious Diseases Section, Veterans Affairs, Palo Alto Health Care System, Palo Alto, CA, USA., Rahman A; Maternal and Child Health Division, International Centre for Diarrhoeal Disease Research, Dhaka, Bangladesh., Brotman RM; Center for Advanced Microbiome Research and Innovation, Institute for Genome Sciences, University of Maryland School of Medicine, Baltimore, MD, USA.; Department of Epidemiology and Public Health, University of Maryland School of Medicine, Baltimore, MD, USA., Price JT; Department of Obstetrics and Gynecology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.; UNC Global Projects-Zambia, Lusaka, Zambia., Kassaro MP; Department of Obstetrics and Gynecology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.; UNC Global Projects-Zambia, Lusaka, Zambia., Holm JB; Center for Advanced Microbiome Research and Innovation, Institute for Genome Sciences, University of Maryland School of Medicine, Baltimore, MD, USA.; Department of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, MD, USA., Ma B; Center for Advanced Microbiome Research and Innovation, Institute for Genome Sciences, University of Maryland School of Medicine, Baltimore, MD, USA.; Department of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, MD, USA., Ravel J; Center for Advanced Microbiome Research and Innovation, Institute for Genome Sciences, University of Maryland School of Medicine, Baltimore, MD, USA. jravel@som.umaryland.edu.; Department of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, MD, USA. jravel@som.umaryland.edu.
Source: Nature communications [Nat Commun] 2025 Dec 06; Vol. 17 (1), pp. 449. Date of Electronic Publication: 2025 Dec 06.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
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  Data: VIRGO2: an enhanced gene catalog of the vaginal microbiome provides insights into its functional and ecology complexity.
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  Data: <searchLink fieldCode="AU" term="%22France+MT%22">France MT</searchLink>; Center for Advanced Microbiome Research and Innovation, Institute for Genome Sciences, University of Maryland School of Medicine, Baltimore, MD, USA.; Department of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, MD, USA.<br /><searchLink fieldCode="AU" term="%22Chaudry+I%22">Chaudry I</searchLink>; Center for Advanced Microbiome Research and Innovation, Institute for Genome Sciences, University of Maryland School of Medicine, Baltimore, MD, USA.; Department of Biochemistry and Molecular Biology, University of Maryland School of Medicine, Baltimore, MD, USA.<br /><searchLink fieldCode="AU" term="%22Rutt+L%22">Rutt L</searchLink>; Center for Advanced Microbiome Research and Innovation, Institute for Genome Sciences, University of Maryland School of Medicine, Baltimore, MD, USA.; Department of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, MD, USA.<br /><searchLink fieldCode="AU" term="%22Quain+M%22">Quain M</searchLink>; Center for Advanced Microbiome Research and Innovation, Institute for Genome Sciences, University of Maryland School of Medicine, Baltimore, MD, USA.; Department of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, MD, USA.<br /><searchLink fieldCode="AU" term="%22Shirtliff+B%22">Shirtliff B</searchLink>; Center for Advanced Microbiome Research and Innovation, Institute for Genome Sciences, University of Maryland School of Medicine, Baltimore, MD, USA.; Department of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, MD, USA.<br /><searchLink fieldCode="AU" term="%22McComb+E%22">McComb E</searchLink>; Center for Advanced Microbiome Research and Innovation, Institute for Genome Sciences, University of Maryland School of Medicine, Baltimore, MD, USA.; Department of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, MD, USA.<br /><searchLink fieldCode="AU" term="%22Maros+A%22">Maros A</searchLink>; Center for Advanced Microbiome Research and Innovation, Institute for Genome Sciences, University of Maryland School of Medicine, Baltimore, MD, USA.; Department of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, MD, USA.<br /><searchLink fieldCode="AU" term="%22Alizadeh+M%22">Alizadeh M</searchLink>; Center for Advanced Microbiome Research and Innovation, Institute for Genome Sciences, University of Maryland School of Medicine, Baltimore, MD, USA.<br /><searchLink fieldCode="AU" term="%22Hussain+FA%22">Hussain FA</searchLink>; Department of Biology, School of Arts and Sciences, Tufts University, Medford, MA, USA.<br /><searchLink fieldCode="AU" term="%22Elovitz+MA%22">Elovitz MA</searchLink>; Women's Biomedical Research Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Department of Obstetrics, Gynecology and Reproductive Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Relman+DA%22">Relman DA</searchLink>; Department of Medicine, Stanford University School of Medicine, Stanford, CA, USA.; Department of Microbiology & Immunology, Stanford University School of Medicine, Stanford, CA, USA.; Infectious Diseases Section, Veterans Affairs, Palo Alto Health Care System, Palo Alto, CA, USA.<br /><searchLink fieldCode="AU" term="%22Rahman+A%22">Rahman A</searchLink>; Maternal and Child Health Division, International Centre for Diarrhoeal Disease Research, Dhaka, Bangladesh.<br /><searchLink fieldCode="AU" term="%22Brotman+RM%22">Brotman RM</searchLink>; Center for Advanced Microbiome Research and Innovation, Institute for Genome Sciences, University of Maryland School of Medicine, Baltimore, MD, USA.; Department of Epidemiology and Public Health, University of Maryland School of Medicine, Baltimore, MD, USA.<br /><searchLink fieldCode="AU" term="%22Price+JT%22">Price JT</searchLink>; Department of Obstetrics and Gynecology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.; UNC Global Projects-Zambia, Lusaka, Zambia.<br /><searchLink fieldCode="AU" term="%22Kassaro+MP%22">Kassaro MP</searchLink>; Department of Obstetrics and Gynecology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.; UNC Global Projects-Zambia, Lusaka, Zambia.<br /><searchLink fieldCode="AU" term="%22Holm+JB%22">Holm JB</searchLink>; Center for Advanced Microbiome Research and Innovation, Institute for Genome Sciences, University of Maryland School of Medicine, Baltimore, MD, USA.; Department of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, MD, USA.<br /><searchLink fieldCode="AU" term="%22Ma+B%22">Ma B</searchLink>; Center for Advanced Microbiome Research and Innovation, Institute for Genome Sciences, University of Maryland School of Medicine, Baltimore, MD, USA.; Department of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, MD, USA.<br /><searchLink fieldCode="AU" term="%22Ravel+J%22">Ravel J</searchLink>; Center for Advanced Microbiome Research and Innovation, Institute for Genome Sciences, University of Maryland School of Medicine, Baltimore, MD, USA. jravel@som.umaryland.edu.; Department of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, MD, USA. jravel@som.umaryland.edu.
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