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Brain glucose extraction is fixed at 10% despite twofold variability in resting cerebral blood flow in healthy humans.

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Title: Brain glucose extraction is fixed at 10% despite twofold variability in resting cerebral blood flow in healthy humans.
Authors: Duffy JS; School of Physical Education, Sport & Exercise Sciences, University of Otago, Dunedin, New Zealand., Caldwell HG; Centre for Heart, Lung and Vascular Health, University of British Columbia - Okanagan Campus, Kelowna, BC, Canada.; The August Krogh Section for Human Physiology, Department of Nutrition, Exercise and Sports, University of Copenhagen, Copenhagen, Denmark., Hoiland RL; Centre for Chronic Disease Prevention and Management, University of British Columbia, Kelowna, BC, Canada.; Department of Cellular and Physiological Sciences, Faculty of Medicine, University of British Columbia, Vancouver, BC, Canada., Howe CA; Centre for Heart, Lung and Vascular Health, University of British Columbia - Okanagan Campus, Kelowna, BC, Canada., Smith KJ; Cerebrovascular Health Exercise and Environmental Research Sciences Laboratory, School of Exercise Science, Physical and Health Education, Faculty of Education, University of Victoria, Victoria, BC, Canada., Bain AR; Department of Kinesiology, Faculty of Human Kinetics, University of Windsor, Windsor, ON, Canada., MacLeod DB; Department of Anesthesiology, Duke University Medical Center, Durham, NC, USA., Ainslie PN; Centre for Heart, Lung and Vascular Health, University of British Columbia - Okanagan Campus, Kelowna, BC, Canada., Gibbons TD; Department of Biological Sciences, Northern Arizona University, Flagstaff, AZ, USA.
Source: Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism [J Cereb Blood Flow Metab] 2026 Mar; Vol. 46 (3), pp. 663-670. Date of Electronic Publication: 2025 Dec 07.
Publication Type: Journal Article
Journal Info: Publisher: SAGE Publications Country of Publication: United States NLM ID: 8112566 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1559-7016 (Electronic) Linking ISSN: 0271678X NLM ISO Abbreviation: J Cereb Blood Flow Metab Subsets: MEDLINE; In Process
Database: MEDLINE Ultimate
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  Data: Brain glucose extraction is fixed at 10% despite twofold variability in resting cerebral blood flow in healthy humans.
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  Data: <searchLink fieldCode="AU" term="%22Duffy+JS%22">Duffy JS</searchLink>; School of Physical Education, Sport & Exercise Sciences, University of Otago, Dunedin, New Zealand.<br /><searchLink fieldCode="AU" term="%22Caldwell+HG%22">Caldwell HG</searchLink>; Centre for Heart, Lung and Vascular Health, University of British Columbia - Okanagan Campus, Kelowna, BC, Canada.; The August Krogh Section for Human Physiology, Department of Nutrition, Exercise and Sports, University of Copenhagen, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Hoiland+RL%22">Hoiland RL</searchLink>; Centre for Chronic Disease Prevention and Management, University of British Columbia, Kelowna, BC, Canada.; Department of Cellular and Physiological Sciences, Faculty of Medicine, University of British Columbia, Vancouver, BC, Canada.<br /><searchLink fieldCode="AU" term="%22Howe+CA%22">Howe CA</searchLink>; Centre for Heart, Lung and Vascular Health, University of British Columbia - Okanagan Campus, Kelowna, BC, Canada.<br /><searchLink fieldCode="AU" term="%22Smith+KJ%22">Smith KJ</searchLink>; Cerebrovascular Health Exercise and Environmental Research Sciences Laboratory, School of Exercise Science, Physical and Health Education, Faculty of Education, University of Victoria, Victoria, BC, Canada.<br /><searchLink fieldCode="AU" term="%22Bain+AR%22">Bain AR</searchLink>; Department of Kinesiology, Faculty of Human Kinetics, University of Windsor, Windsor, ON, Canada.<br /><searchLink fieldCode="AU" term="%22MacLeod+DB%22">MacLeod DB</searchLink>; Department of Anesthesiology, Duke University Medical Center, Durham, NC, USA.<br /><searchLink fieldCode="AU" term="%22Ainslie+PN%22">Ainslie PN</searchLink>; Centre for Heart, Lung and Vascular Health, University of British Columbia - Okanagan Campus, Kelowna, BC, Canada.<br /><searchLink fieldCode="AU" term="%22Gibbons+TD%22">Gibbons TD</searchLink>; Department of Biological Sciences, Northern Arizona University, Flagstaff, AZ, USA.
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  Data: <searchLink fieldCode="JN" term="%228112566%22">Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism</searchLink> [J Cereb Blood Flow Metab] 2026 Mar; Vol. 46 (3), pp. 663-670. <i>Date of Electronic Publication: </i>2025 Dec 07.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22SAGE+Publications%22">SAGE Publications </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>8112566 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1559-7016 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%220271678X%22">0271678X </searchLink><i>NLM ISO Abbreviation: </i>J Cereb Blood Flow Metab <i>Subsets: </i>MEDLINE; In Process
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        Value: 10.1177/0271678X251400247
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              Text: 2026 Mar
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