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Fluorinated pyrimidine 5-carboxamides as potential tools for MERTK targeted fluorine-18-PET-radioligand development.

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Title: Fluorinated pyrimidine 5-carboxamides as potential tools for MERTK targeted fluorine-18-PET-radioligand development.
Authors: Mudududdla R; Medicinal Chemistry, Monash Institute of Pharmaceutical Sciences, Monash University Parkville Victoria 3052 Australia jbaell29@gmail.com., Wong SW; Medicinal Chemistry, Monash Institute of Pharmaceutical Sciences, Monash University Parkville Victoria 3052 Australia jbaell29@gmail.com., Nguyen N; Medicinal Chemistry, Monash Institute of Pharmaceutical Sciences, Monash University Parkville Victoria 3052 Australia jbaell29@gmail.com., Xue L; Medicinal Chemistry, Monash Institute of Pharmaceutical Sciences, Monash University Parkville Victoria 3052 Australia jbaell29@gmail.com., Stashko MA; Center for Integrative Chemical Biology and Drug Discovery, Division of Chemical Biology and Medicinal Chemistry, Eshelman School of Pharmacy, University of North Carolina at Chapel Hill Chapel Hill NC 27599 USA., Wang X; Center for Integrative Chemical Biology and Drug Discovery, Division of Chemical Biology and Medicinal Chemistry, Eshelman School of Pharmacy, University of North Carolina at Chapel Hill Chapel Hill NC 27599 USA., Vivash L; Department of Neuroscience, School of Translational Medicine, Monash University Melbourne Victoria 3010 Australia., Binder MD; Florey Institute of Neuroscience and Mental Health Parkville Victoria 3010 Australia., Ackermann U; Department of Nuclear Medicine and Centre for PET, Austin Health Heidelberg Victoria 3084 Australia., Bozikis YE; Medicinal Chemistry, Monash Institute of Pharmaceutical Sciences, Monash University Parkville Victoria 3052 Australia jbaell29@gmail.com., Kilpatrick TJ; The Florey Department of Neuroscience and Mental Health, University of Melbourne Parkville Victoria 3010 Australia tkilpat@florey.edu.au., Baell JB; Medicinal Chemistry, Monash Institute of Pharmaceutical Sciences, Monash University Parkville Victoria 3052 Australia jbaell29@gmail.com.
Source: RSC medicinal chemistry [RSC Med Chem] 2025 Dec 03. Date of Electronic Publication: 2025 Dec 03.
Publication Type: Journal Article
Journal Info: Publisher: Royal Society of Chemistry Country of Publication: England NLM ID: 101759460 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2632-8682 (Electronic) Linking ISSN: 26328682 NLM ISO Abbreviation: RSC Med Chem
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  Data: Fluorinated pyrimidine 5-carboxamides as potential tools for MERTK targeted fluorine-18-PET-radioligand development.
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  Data: <searchLink fieldCode="AU" term="%22Mudududdla+R%22">Mudududdla R</searchLink>; Medicinal Chemistry, Monash Institute of Pharmaceutical Sciences, Monash University Parkville Victoria 3052 Australia jbaell29@gmail.com.<br /><searchLink fieldCode="AU" term="%22Wong+SW%22">Wong SW</searchLink>; Medicinal Chemistry, Monash Institute of Pharmaceutical Sciences, Monash University Parkville Victoria 3052 Australia jbaell29@gmail.com.<br /><searchLink fieldCode="AU" term="%22Nguyen+N%22">Nguyen N</searchLink>; Medicinal Chemistry, Monash Institute of Pharmaceutical Sciences, Monash University Parkville Victoria 3052 Australia jbaell29@gmail.com.<br /><searchLink fieldCode="AU" term="%22Xue+L%22">Xue L</searchLink>; Medicinal Chemistry, Monash Institute of Pharmaceutical Sciences, Monash University Parkville Victoria 3052 Australia jbaell29@gmail.com.<br /><searchLink fieldCode="AU" term="%22Stashko+MA%22">Stashko MA</searchLink>; Center for Integrative Chemical Biology and Drug Discovery, Division of Chemical Biology and Medicinal Chemistry, Eshelman School of Pharmacy, University of North Carolina at Chapel Hill Chapel Hill NC 27599 USA.<br /><searchLink fieldCode="AU" term="%22Wang+X%22">Wang X</searchLink>; Center for Integrative Chemical Biology and Drug Discovery, Division of Chemical Biology and Medicinal Chemistry, Eshelman School of Pharmacy, University of North Carolina at Chapel Hill Chapel Hill NC 27599 USA.<br /><searchLink fieldCode="AU" term="%22Vivash+L%22">Vivash L</searchLink>; Department of Neuroscience, School of Translational Medicine, Monash University Melbourne Victoria 3010 Australia.<br /><searchLink fieldCode="AU" term="%22Binder+MD%22">Binder MD</searchLink>; Florey Institute of Neuroscience and Mental Health Parkville Victoria 3010 Australia.<br /><searchLink fieldCode="AU" term="%22Ackermann+U%22">Ackermann U</searchLink>; Department of Nuclear Medicine and Centre for PET, Austin Health Heidelberg Victoria 3084 Australia.<br /><searchLink fieldCode="AU" term="%22Bozikis+YE%22">Bozikis YE</searchLink>; Medicinal Chemistry, Monash Institute of Pharmaceutical Sciences, Monash University Parkville Victoria 3052 Australia jbaell29@gmail.com.<br /><searchLink fieldCode="AU" term="%22Kilpatrick+TJ%22">Kilpatrick TJ</searchLink>; The Florey Department of Neuroscience and Mental Health, University of Melbourne Parkville Victoria 3010 Australia tkilpat@florey.edu.au.<br /><searchLink fieldCode="AU" term="%22Baell+JB%22">Baell JB</searchLink>; Medicinal Chemistry, Monash Institute of Pharmaceutical Sciences, Monash University Parkville Victoria 3052 Australia jbaell29@gmail.com.
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  Data: <searchLink fieldCode="JN" term="%22101759460%22">RSC medicinal chemistry</searchLink> [RSC Med Chem] 2025 Dec 03. <i>Date of Electronic Publication: </i>2025 Dec 03.
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              Text: 2025 Dec 03
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