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The Effect of Local Infiltration of Dexmedetomidine as an Adjuvant on Breakthrough Pain During Epidural Labor Analgesia: A Randomized Controlled Trial.

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Title: The Effect of Local Infiltration of Dexmedetomidine as an Adjuvant on Breakthrough Pain During Epidural Labor Analgesia: A Randomized Controlled Trial.
Authors: Liu D; Department of Anesthesiology, the Third Affiliated Hospital of Anhui Medical University (The First People's Hospital of Hefei), Hefei, Anhui, People's Republic of China., Wang X; Department of Anesthesiology, the Third Affiliated Hospital of Anhui Medical University (The First People's Hospital of Hefei), Hefei, Anhui, People's Republic of China., Wu XX; Department of Anesthesiology, the Maternal and Child Health Hospital of Anhui Medical University, Hefei, Anhui, People's Republic of China., Ouyang RN; Department of Anesthesiology, the Third Affiliated Hospital of Anhui Medical University (The First People's Hospital of Hefei), Hefei, Anhui, People's Republic of China., Niu JY; Department of Anesthesiology, the Third Affiliated Hospital of Anhui Medical University (The First People's Hospital of Hefei), Hefei, Anhui, People's Republic of China., Tao QY; Department of Anesthesiology, the Third Affiliated Hospital of Anhui Medical University (The First People's Hospital of Hefei), Hefei, Anhui, People's Republic of China., Wang YH; Department of Anesthesiology, the Third Affiliated Hospital of Anhui Medical University (The First People's Hospital of Hefei), Hefei, Anhui, People's Republic of China., Wang J; Department of Anesthesiology, the Third Affiliated Hospital of Anhui Medical University (The First People's Hospital of Hefei), Hefei, Anhui, People's Republic of China., Zhu H; Department of Anesthesiology, the Third Affiliated Hospital of Anhui Medical University (The First People's Hospital of Hefei), Hefei, Anhui, People's Republic of China., Zhang F; Department of Birthing Center, the Maternal and Child Health Hospital of Anhui Medical University, Hefei, Anhui, People's Republic of China., Zhu HJ; Department of Anesthesiology, the Maternal and Child Health Hospital of Anhui Medical University, Hefei, Anhui, People's Republic of China., Yu JM; Department of Anesthesiology, the Third Affiliated Hospital of Anhui Medical University (The First People's Hospital of Hefei), Hefei, Anhui, People's Republic of China.
Source: Drug design, development and therapy [Drug Des Devel Ther] 2025 Dec 02; Vol. 19, pp. 10621-10631. Date of Electronic Publication: 2025 Dec 02 (Print Publication: 2025).
Publication Type: Journal Article; Randomized Controlled Trial
Journal Info: Publisher: Dove Press Limited Country of Publication: New Zealand NLM ID: 101475745 Publication Model: eCollection Cited Medium: Internet ISSN: 1177-8881 (Electronic) Linking ISSN: 11778881 NLM ISO Abbreviation: Drug Des Devel Ther Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: The Effect of Local Infiltration of Dexmedetomidine as an Adjuvant on Breakthrough Pain During Epidural Labor Analgesia: A Randomized Controlled Trial.
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  Data: <searchLink fieldCode="AU" term="%22Liu+D%22">Liu D</searchLink>; Department of Anesthesiology, the Third Affiliated Hospital of Anhui Medical University (The First People's Hospital of Hefei), Hefei, Anhui, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Wang+X%22">Wang X</searchLink>; Department of Anesthesiology, the Third Affiliated Hospital of Anhui Medical University (The First People's Hospital of Hefei), Hefei, Anhui, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Wu+XX%22">Wu XX</searchLink>; Department of Anesthesiology, the Maternal and Child Health Hospital of Anhui Medical University, Hefei, Anhui, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Ouyang+RN%22">Ouyang RN</searchLink>; Department of Anesthesiology, the Third Affiliated Hospital of Anhui Medical University (The First People's Hospital of Hefei), Hefei, Anhui, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Niu+JY%22">Niu JY</searchLink>; Department of Anesthesiology, the Third Affiliated Hospital of Anhui Medical University (The First People's Hospital of Hefei), Hefei, Anhui, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Tao+QY%22">Tao QY</searchLink>; Department of Anesthesiology, the Third Affiliated Hospital of Anhui Medical University (The First People's Hospital of Hefei), Hefei, Anhui, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Wang+YH%22">Wang YH</searchLink>; Department of Anesthesiology, the Third Affiliated Hospital of Anhui Medical University (The First People's Hospital of Hefei), Hefei, Anhui, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Wang+J%22">Wang J</searchLink>; Department of Anesthesiology, the Third Affiliated Hospital of Anhui Medical University (The First People's Hospital of Hefei), Hefei, Anhui, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Zhu+H%22">Zhu H</searchLink>; Department of Anesthesiology, the Third Affiliated Hospital of Anhui Medical University (The First People's Hospital of Hefei), Hefei, Anhui, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Zhang+F%22">Zhang F</searchLink>; Department of Birthing Center, the Maternal and Child Health Hospital of Anhui Medical University, Hefei, Anhui, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Zhu+HJ%22">Zhu HJ</searchLink>; Department of Anesthesiology, the Maternal and Child Health Hospital of Anhui Medical University, Hefei, Anhui, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Yu+JM%22">Yu JM</searchLink>; Department of Anesthesiology, the Third Affiliated Hospital of Anhui Medical University (The First People's Hospital of Hefei), Hefei, Anhui, People's Republic of China.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Dove+Press+Limited%22">Dove Press Limited </searchLink><i>Country of Publication: </i>New Zealand <i>NLM ID: </i>101475745 <i>Publication Model: </i>eCollection <i>Cited Medium: </i>Internet <i>ISSN: </i>1177-8881 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2211778881%22">11778881 </searchLink><i>NLM ISO Abbreviation: </i>Drug Des Devel Ther <i>Subsets: </i>MEDLINE
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        Value: 10.2147/DDDT.S553879
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              Text: 2025 Dec 02
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