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Aprocitentan in Patients With Chronic Kidney Disease and Resistant Hypertension.

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Title: Aprocitentan in Patients With Chronic Kidney Disease and Resistant Hypertension.
Authors: Rossignol P; Université de Lorraine, Institut National de la Santé et de la Recherche Médicale (INSERM), Centre d'Investigations Cliniques-Plurithématique 1433, INSERM Unit 1116, Centre Hospitalier Régional Universitaire (CHRU) de Nancy, and French Clinical Research Infrastructure Network Investigator Network initiative Cardiovascular and Renal Clinical Trialists (F-CRIN INI-CRCT), Nancy, France (P.R.).; Medical specialties and nephrology departments, Princess Grace Hospital, and Monaco Private Hemodialysis Centre, Monaco, and Monaco Clinical Research Infrastructure Network (M-CRIN), Monaco (P.R.)., Clozel M; Idorsia Pharmaceuticals Ltd, Allschwil, Switzerland (M.C.)., Dreier RF; Novartis Pharmaceuticals AG, Basel, Switzerland (R.F.D.)., Flack JM; Division of General Internal Medicine, Hypertension Section, Department of Medicine, Hypertension Section, Southern Illinois University School of Medicine, Springfield, IL (J.M.F.)., Flamion B; Viatris Innovation GmbH, Allschwil, Switzerland (B.F., M.S.-S.)., Mann J; Department of Medicine, Universitätsklinikum Erlangen, Germany (J.M.).; Outpatient Clinic, KfH Kidney Centre, Munich, Germany (J.M.)., Narkiewicz K; Department of Hypertension and Diabetology, Medical University of Gdańsk, Poland (K.N.)., Sassi-Sayadi M; Viatris Innovation GmbH, Allschwil, Switzerland (B.F., M.S.-S.)., Wang JG; Department of Hypertension, The Shanghai Institute of Hypertension, Rui Jin Hospital, Shanghai Jiaotong University School of Medicine, China (J.-G.W.)., Weber MA; Division of Cardiovascular Medicine, Downstate College of Medicine, State University of New York, Brooklyn (M.A.W.)., Schlaich MP; Dobney Hypertension Centre, Royal Perth Hospital Research Foundation, Medical School, University of Western Australia, Perth, Australia (M.P.S.).; Department of Cardiology and Department of Nephrology, Royal Perth Hospital, WA, Australia (M.P.S.).
Source: Hypertension (Dallas, Tex. : 1979) [Hypertension] 2026 Feb; Vol. 83 (2), pp. e25563. Date of Electronic Publication: 2025 Dec 09.
Publication Type: Journal Article; Randomized Controlled Trial; Clinical Trial, Phase III; Multicenter Study
Journal Info: Publisher: Lippincott, Williams & Wilkins Country of Publication: United States NLM ID: 7906255 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1524-4563 (Electronic) Linking ISSN: 0194911X NLM ISO Abbreviation: Hypertension Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Aprocitentan in Patients With Chronic Kidney Disease and Resistant Hypertension.
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  Data: <searchLink fieldCode="AU" term="%22Rossignol+P%22">Rossignol P</searchLink>; Université de Lorraine, Institut National de la Santé et de la Recherche Médicale (INSERM), Centre d'Investigations Cliniques-Plurithématique 1433, INSERM Unit 1116, Centre Hospitalier Régional Universitaire (CHRU) de Nancy, and French Clinical Research Infrastructure Network Investigator Network initiative Cardiovascular and Renal Clinical Trialists (F-CRIN INI-CRCT), Nancy, France (P.R.).; Medical specialties and nephrology departments, Princess Grace Hospital, and Monaco Private Hemodialysis Centre, Monaco, and Monaco Clinical Research Infrastructure Network (M-CRIN), Monaco (P.R.).<br /><searchLink fieldCode="AU" term="%22Clozel+M%22">Clozel M</searchLink>; Idorsia Pharmaceuticals Ltd, Allschwil, Switzerland (M.C.).<br /><searchLink fieldCode="AU" term="%22Dreier+RF%22">Dreier RF</searchLink>; Novartis Pharmaceuticals AG, Basel, Switzerland (R.F.D.).<br /><searchLink fieldCode="AU" term="%22Flack+JM%22">Flack JM</searchLink>; Division of General Internal Medicine, Hypertension Section, Department of Medicine, Hypertension Section, Southern Illinois University School of Medicine, Springfield, IL (J.M.F.).<br /><searchLink fieldCode="AU" term="%22Flamion+B%22">Flamion B</searchLink>; Viatris Innovation GmbH, Allschwil, Switzerland (B.F., M.S.-S.).<br /><searchLink fieldCode="AU" term="%22Mann+J%22">Mann J</searchLink>; Department of Medicine, Universitätsklinikum Erlangen, Germany (J.M.).; Outpatient Clinic, KfH Kidney Centre, Munich, Germany (J.M.).<br /><searchLink fieldCode="AU" term="%22Narkiewicz+K%22">Narkiewicz K</searchLink>; Department of Hypertension and Diabetology, Medical University of Gdańsk, Poland (K.N.).<br /><searchLink fieldCode="AU" term="%22Sassi-Sayadi+M%22">Sassi-Sayadi M</searchLink>; Viatris Innovation GmbH, Allschwil, Switzerland (B.F., M.S.-S.).<br /><searchLink fieldCode="AU" term="%22Wang+JG%22">Wang JG</searchLink>; Department of Hypertension, The Shanghai Institute of Hypertension, Rui Jin Hospital, Shanghai Jiaotong University School of Medicine, China (J.-G.W.).<br /><searchLink fieldCode="AU" term="%22Weber+MA%22">Weber MA</searchLink>; Division of Cardiovascular Medicine, Downstate College of Medicine, State University of New York, Brooklyn (M.A.W.).<br /><searchLink fieldCode="AU" term="%22Schlaich+MP%22">Schlaich MP</searchLink>; Dobney Hypertension Centre, Royal Perth Hospital Research Foundation, Medical School, University of Western Australia, Perth, Australia (M.P.S.).; Department of Cardiology and Department of Nephrology, Royal Perth Hospital, WA, Australia (M.P.S.).
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  Data: <searchLink fieldCode="JN" term="%227906255%22">Hypertension (Dallas, Tex. : 1979)</searchLink> [Hypertension] 2026 Feb; Vol. 83 (2), pp. e25563. <i>Date of Electronic Publication: </i>2025 Dec 09.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Lippincott%2C+Williams+%26+Wilkins%22">Lippincott, Williams & Wilkins </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>7906255 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1524-4563 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%220194911X%22">0194911X </searchLink><i>NLM ISO Abbreviation: </i>Hypertension <i>Subsets: </i>MEDLINE
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        Value: 10.1161/HYPERTENSIONAHA.125.25563
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              Text: 2026 Feb
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              Y: 2026
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