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Expectant Management vs Medication for Patent Ductus Arteriosus in Preterm Infants: The PDA Randomized Clinical Trial.

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Title: Expectant Management vs Medication for Patent Ductus Arteriosus in Preterm Infants: The PDA Randomized Clinical Trial.
Authors: Laughon MM; Department of Pediatrics, University of North Carolina at Chapel Hill., Thomas SM; Biostatistics and Epidemiology Division, RTI International, Research Triangle Park, North Carolina., Watterberg KL; Department of Pediatrics, University of New Mexico Health Sciences Center, Albuquerque., Kennedy KA; McGovern Medical School, University of Texas Health Science Center, Houston., Keszler M; Department of Pediatrics, Warren Alpert Medical School, Brown University, Providence, Rhode Island., Ambalavanan N; Division of Neonatology, University of Alabama, Birmingham., Davis AS; Lucile Packard Children's Hospital Stanford, Stanford University, Palo Alto, California., Slaughter JL; Nationwide Children's Hospital, College of Medicine, Ohio State University, Columbus., Guillet R; Division of Neonatology, School of Medicine and Dentistry, University of Rochester, Rochester, New York., Colaizy TT; Department of Pediatrics, University of Iowa, Iowa City., Cotten CM; Department of Pediatrics, Duke University, Durham, North Carolina., Dhawan MA; Children's Hospital of Philadelphia, University of Pennsylvania, Philadelphia., Bose CL; Department of Pediatrics, University of North Carolina at Chapel Hill., Talbert J; Department of Pediatrics, University of North Carolina at Chapel Hill.; Biostatistics and Epidemiology Division, RTI International, Research Triangle Park, North Carolina., Smucny S; Rainbow Babies and Children's Hospital, Case Western Reserve University, Cleveland, Ohio., Benitz WE; Lucile Packard Children's Hospital Stanford, Stanford University, Palo Alto, California., Rysavy MA; McGovern Medical School, University of Texas Health Science Center, Houston., Ohls RK; University of Utah Health Sciences Center, Salt Lake City., Baserga MC; University of Utah Health Sciences Center, Salt Lake City., DeMauro SB; Hospital of the University of Pennsylvania, Philadelphia., Jaleel M; Parkland Memorial Hospital, University of Texas Southwestern Medical Center, Dallas., Jackson WM; Department of Pediatrics, University of North Carolina at Chapel Hill., Carlo WA; Division of Neonatology, University of Alabama, Birmingham., Puopolo KM; Pennsylvania Hospital, Philadelphia., Hibbs AM; Rainbow Babies and Children's Hospital, Case Western Reserve University, Cleveland, Ohio., Katheria A; Sharp Mary Birch Hospital for Women and Newborns, San Diego, California., Sánchez PJ; Nationwide Children's Hospital, College of Medicine, Ohio State University, Columbus., D'Angio CT; Division of Neonatology, School of Medicine and Dentistry, University of Rochester, Rochester, New York., Patel RM; Department of Pediatrics, Emory University, Atlanta, Georgia., Johnson BA; Good Samaritan Hospital, Cincinnati, Ohio., Chock VY; Lucile Packard Children's Hospital Stanford, Stanford University, Palo Alto, California., Bhatt AJ; Department of Pediatrics, University of Mississippi Medical Center, Jackson., Merhar SL; University of Cincinnati Hospital, Cincinnati, Ohio., Moore R; Maynard Children's Hospital, East Carolina University Health, Greenville, North Carolina., Laptook AR; Department of Pediatrics, Warren Alpert Medical School, Brown University, Providence, Rhode Island., Ghavam S; Virtua Voorhees Hospital, Voorhees, New Jersey., Fuller J; Department of Pediatrics, University of New Mexico Health Sciences Center, Albuquerque., Vyas-Read S; Grady Memorial Hospital, Emory University, Atlanta, Georgia., Kicklighter SD; WakeMed Health and Hospitals, Raleigh, North Carolina., Steinbrekera B; Sanford Health, Sioux Falls, South Dakota., Anderson K; Sanford Health, Sioux Falls, South Dakota., Chandrasekharan PK; Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, Buffalo, New York., Wyckoff MH; William P. Clements Jr University Hospital, Dallas, Texas., Montoya C; Prentice Women's Hospital, Northwestern University, Chicago, Illinois., Das A; Social, Statistical, and Environmental Sciences Unit, RTI International, Rockville, Maryland., Do B; Biostatistics and Epidemiology Division, RTI International, Research Triangle Park, North Carolina., Chang S; Biostatistics and Epidemiology Division, RTI International, Research Triangle Park, North Carolina., Higgins RD; Eunice Kennedy Shriver National Institute of Child Health and Human Development, Bethesda, Maryland.; Research and Sponsored Programs, Florida Gulf Coast University, Fort Myers., Walsh MC; Eunice Kennedy Shriver National Institute of Child Health and Human Development, Bethesda, Maryland.
Corporate Authors: Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network
Source: JAMA [JAMA] 2026 Feb 17; Vol. 335 (7), pp. 588-599.
Publication Type: Clinical Trial, Phase III; Comparative Study; Journal Article; Multicenter Study; Pragmatic Clinical Trial; Randomized Controlled Trial
Journal Info: Publisher: American Medical Association Country of Publication: United States NLM ID: 7501160 Publication Model: Print Cited Medium: Internet ISSN: 1538-3598 (Electronic) Linking ISSN: 00987484 NLM ISO Abbreviation: JAMA Subsets: MEDLINE
Database: MEDLINE Ultimate
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