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Effectiveness and Safety of High-Dose versus Standard-Dose Cefoperazone-Sulbactam in Severe Infections: A Multicenter Retrospective Study.

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Title: Effectiveness and Safety of High-Dose versus Standard-Dose Cefoperazone-Sulbactam in Severe Infections: A Multicenter Retrospective Study.
Authors: Li CH; Division of Infectious Diseases, Department of Medicine, Chi Mei Medical Center, Tainan, 710402, Taiwan., Hsu CK; Division of Pulmonary Medicine, Department of Internal Medicine, E-Da Hospital, I-Shou University, Kaohsiung, 824005, Taiwan., Lai CC; Division of Intensive Care Medicine, Chi Mei Medical Center, Tainan, 710402, Taiwan., Liu JW; Division of Infectious Diseases, Department of Medicine, Chi Mei Medical Center, Tainan, 710402, Taiwan., Tang HJ; Division of Infectious Diseases, Department of Medicine, Chi Mei Medical Center, Tainan, 710402, Taiwan., Liao KM; Department of Internal Medicine, Chi Mei Medical Center, Tainan, 722013, Taiwan., Chang PC; Division of Infectious Disease, Department of Internal Medicine, Chi Mei Medical Center, Tainan, 736002, Taiwan., Ku YH; Division of Infectious Disease, Department of Internal Medicine, Chi Mei Medical Center, Tainan, 736002, Taiwan., Chiu YH; Division of Infectious Disease, Department of Internal Medicine, Chi Mei Medical Center, Tainan, 736002, Taiwan., Chiu CT; Division of Pulmonary Medicine, Department of Internal Medicine, E-Da Hospital, I-Shou University, Kaohsiung, 824005, Taiwan.
Source: Infection and drug resistance [Infect Drug Resist] 2025 Dec 03; Vol. 18, pp. 6269-6278. Date of Electronic Publication: 2025 Dec 03 (Print Publication: 2025).
Publication Type: Journal Article
Journal Info: Publisher: Dove Medical Press Country of Publication: New Zealand NLM ID: 101550216 Publication Model: eCollection Cited Medium: Print ISSN: 1178-6973 (Print) Linking ISSN: 11786973 NLM ISO Abbreviation: Infect Drug Resist Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: Effectiveness and Safety of High-Dose versus Standard-Dose Cefoperazone-Sulbactam in Severe Infections: A Multicenter Retrospective Study.
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  Data: <searchLink fieldCode="AU" term="%22Li+CH%22">Li CH</searchLink>; Division of Infectious Diseases, Department of Medicine, Chi Mei Medical Center, Tainan, 710402, Taiwan.<br /><searchLink fieldCode="AU" term="%22Hsu+CK%22">Hsu CK</searchLink>; Division of Pulmonary Medicine, Department of Internal Medicine, E-Da Hospital, I-Shou University, Kaohsiung, 824005, Taiwan.<br /><searchLink fieldCode="AU" term="%22Lai+CC%22">Lai CC</searchLink>; Division of Intensive Care Medicine, Chi Mei Medical Center, Tainan, 710402, Taiwan.<br /><searchLink fieldCode="AU" term="%22Liu+JW%22">Liu JW</searchLink>; Division of Infectious Diseases, Department of Medicine, Chi Mei Medical Center, Tainan, 710402, Taiwan.<br /><searchLink fieldCode="AU" term="%22Tang+HJ%22">Tang HJ</searchLink>; Division of Infectious Diseases, Department of Medicine, Chi Mei Medical Center, Tainan, 710402, Taiwan.<br /><searchLink fieldCode="AU" term="%22Liao+KM%22">Liao KM</searchLink>; Department of Internal Medicine, Chi Mei Medical Center, Tainan, 722013, Taiwan.<br /><searchLink fieldCode="AU" term="%22Chang+PC%22">Chang PC</searchLink>; Division of Infectious Disease, Department of Internal Medicine, Chi Mei Medical Center, Tainan, 736002, Taiwan.<br /><searchLink fieldCode="AU" term="%22Ku+YH%22">Ku YH</searchLink>; Division of Infectious Disease, Department of Internal Medicine, Chi Mei Medical Center, Tainan, 736002, Taiwan.<br /><searchLink fieldCode="AU" term="%22Chiu+YH%22">Chiu YH</searchLink>; Division of Infectious Disease, Department of Internal Medicine, Chi Mei Medical Center, Tainan, 736002, Taiwan.<br /><searchLink fieldCode="AU" term="%22Chiu+CT%22">Chiu CT</searchLink>; Division of Pulmonary Medicine, Department of Internal Medicine, E-Da Hospital, I-Shou University, Kaohsiung, 824005, Taiwan.
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  Data: <searchLink fieldCode="JN" term="%22101550216%22">Infection and drug resistance</searchLink> [Infect Drug Resist] 2025 Dec 03; Vol. 18, pp. 6269-6278. <i>Date of Electronic Publication: </i>2025 Dec 03 (<i>Print Publication: </i>2025).
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Dove+Medical+Press%22">Dove Medical Press </searchLink><i>Country of Publication: </i>New Zealand <i>NLM ID: </i>101550216 <i>Publication Model: </i>eCollection <i>Cited Medium: </i>Print <i>ISSN: </i>1178-6973 (Print) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2211786973%22">11786973 </searchLink><i>NLM ISO Abbreviation: </i>Infect Drug Resist <i>Subsets: </i>PubMed not MEDLINE
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        Value: 10.2147/IDR.S551491
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        Text: English
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              Text: 2025 Dec 03
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