Aldosterone antagonist combined with a SGLT2 inhibitor versus SGLT2 inhibitor monotherapy: An updated meta-analysis.

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Title: Aldosterone antagonist combined with a SGLT2 inhibitor versus SGLT2 inhibitor monotherapy: An updated meta-analysis.
Authors: Mendonça L; RISE-Health, Department of Surgery and Physiology, Faculty of Medicine, University of Porto, Porto, Portugal.; Nephrology Department, Unidade Local de Saúde de São João, Porto, Portugal., Neves JS; RISE-Health, Department of Surgery and Physiology, Faculty of Medicine, University of Porto, Porto, Portugal.; Endocrinology Department, Unidade Local de Saúde de São João, Porto, Portugal., Vasques-Nóvoa F; RISE-Health, Department of Surgery and Physiology, Faculty of Medicine, University of Porto, Porto, Portugal.; Internal Medicine Department, Unidade Local de Saúde de São João, Porto, Portugal., Leite AR; RISE-Health, Department of Surgery and Physiology, Faculty of Medicine, University of Porto, Porto, Portugal.; Endocrinology Department, Unidade Local de Saúde de São João, Porto, Portugal., Marques P; RISE-Health, Department of Surgery and Physiology, Faculty of Medicine, University of Porto, Porto, Portugal.; Internal Medicine Department, Unidade Local de Saúde de São João, Porto, Portugal., Ferreira JP; RISE-Health, Department of Surgery and Physiology, Faculty of Medicine, University of Porto, Porto, Portugal.; Centre d'Investigations Cliniques, Université de Lorraine, Inserm, Plurithématique 14-33, and Inserm U1116, CHRU Nancy, F-CRIN INI-CRCT (Cardiovascular and Renal Clinical Trialists), Nancy, France.; Heart Failure Clinic, Internal Medicine Department, Unidade Local de Saude de Gaia, Espinho, Portugal.
Source: Diabetes, obesity & metabolism [Diabetes Obes Metab] 2026 Mar; Vol. 28 (3), pp. 2443-2448. Date of Electronic Publication: 2025 Dec 10.
Publication Type: Letter
Journal Info: Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 100883645 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1463-1326 (Electronic) Linking ISSN: 14628902 NLM ISO Abbreviation: Diabetes Obes Metab Subsets: MEDLINE; In Process
Database: MEDLINE Ultimate
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