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Adaptations of the axon initial segment in fast-spiking interneurons of the human neocortex support low action potential thresholds.

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Title: Adaptations of the axon initial segment in fast-spiking interneurons of the human neocortex support low action potential thresholds.
Authors: Bakos E; Hungarian Center of Excellence for Molecular Medicine Research Group for Human Neuron Physiology and Therapy, Szeged, Hungary.; Department of Physiology, Anatomy and Neuroscience, University of Szeged, Szeged, Hungary., Tiszlavicz Á; Hungarian Center of Excellence for Molecular Medicine Research Group for Human Neuron Physiology and Therapy, Szeged, Hungary., Szegedi V; Hungarian Center of Excellence for Molecular Medicine Research Group for Human Neuron Physiology and Therapy, Szeged, Hungary.; Department of Physiology, Anatomy and Neuroscience, University of Szeged, Szeged, Hungary., Douida A; Hungarian Center of Excellence for Molecular Medicine Research Group for Human Neuron Physiology and Therapy, Szeged, Hungary., Furdan S; Hungarian Center of Excellence for Molecular Medicine Research Group for Human Neuron Physiology and Therapy, Szeged, Hungary., Welter DK; European Molecular Biology Laboratory, Heidelberg, Germany., Landry JM; European Molecular Biology Laboratory, Heidelberg, Germany., Bende B; Hungarian Centre of Excellence for Molecular Medicine Research Group for Translational Medicine Development, Szeged, Hungary., Hutoczki G; Department of Neurosurgery, University of Debrecen Clinical Centre, Debrecen Hungary., Barzo P; Department of Neurosurgery, University of Szeged, Szeged, Hungary., Tamas G; ELKH-SZTE Research Group for Cortical Microcircuits, Department of Physiology, Anatomy and Neuroscience, University of Szeged, Szeged, Hungary., Benes V; European Molecular Biology Laboratory, Heidelberg, Germany., Szucs A; Neuronal Cell Biology Research Group, Eötvös Loránd University, Budapest, Hungary., Lamsa K; Hungarian Center of Excellence for Molecular Medicine Research Group for Human Neuron Physiology and Therapy, Szeged, Hungary.; Department of Physiology, Anatomy and Neuroscience, University of Szeged, Szeged, Hungary.
Source: PLoS biology [PLoS Biol] 2025 Dec 10; Vol. 23 (12), pp. e3003549. Date of Electronic Publication: 2025 Dec 10 (Print Publication: 2025).
Publication Type: Journal Article
Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101183755 Publication Model: eCollection Cited Medium: Internet ISSN: 1545-7885 (Electronic) Linking ISSN: 15449173 NLM ISO Abbreviation: PLoS Biol Subsets: MEDLINE
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  Data: Adaptations of the axon initial segment in fast-spiking interneurons of the human neocortex support low action potential thresholds.
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  Data: <searchLink fieldCode="AU" term="%22Bakos+E%22">Bakos E</searchLink>; Hungarian Center of Excellence for Molecular Medicine Research Group for Human Neuron Physiology and Therapy, Szeged, Hungary.; Department of Physiology, Anatomy and Neuroscience, University of Szeged, Szeged, Hungary.<br /><searchLink fieldCode="AU" term="%22Tiszlavicz+Á%22">Tiszlavicz Á</searchLink>; Hungarian Center of Excellence for Molecular Medicine Research Group for Human Neuron Physiology and Therapy, Szeged, Hungary.<br /><searchLink fieldCode="AU" term="%22Szegedi+V%22">Szegedi V</searchLink>; Hungarian Center of Excellence for Molecular Medicine Research Group for Human Neuron Physiology and Therapy, Szeged, Hungary.; Department of Physiology, Anatomy and Neuroscience, University of Szeged, Szeged, Hungary.<br /><searchLink fieldCode="AU" term="%22Douida+A%22">Douida A</searchLink>; Hungarian Center of Excellence for Molecular Medicine Research Group for Human Neuron Physiology and Therapy, Szeged, Hungary.<br /><searchLink fieldCode="AU" term="%22Furdan+S%22">Furdan S</searchLink>; Hungarian Center of Excellence for Molecular Medicine Research Group for Human Neuron Physiology and Therapy, Szeged, Hungary.<br /><searchLink fieldCode="AU" term="%22Welter+DK%22">Welter DK</searchLink>; European Molecular Biology Laboratory, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Landry+JM%22">Landry JM</searchLink>; European Molecular Biology Laboratory, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Bende+B%22">Bende B</searchLink>; Hungarian Centre of Excellence for Molecular Medicine Research Group for Translational Medicine Development, Szeged, Hungary.<br /><searchLink fieldCode="AU" term="%22Hutoczki+G%22">Hutoczki G</searchLink>; Department of Neurosurgery, University of Debrecen Clinical Centre, Debrecen Hungary.<br /><searchLink fieldCode="AU" term="%22Barzo+P%22">Barzo P</searchLink>; Department of Neurosurgery, University of Szeged, Szeged, Hungary.<br /><searchLink fieldCode="AU" term="%22Tamas+G%22">Tamas G</searchLink>; ELKH-SZTE Research Group for Cortical Microcircuits, Department of Physiology, Anatomy and Neuroscience, University of Szeged, Szeged, Hungary.<br /><searchLink fieldCode="AU" term="%22Benes+V%22">Benes V</searchLink>; European Molecular Biology Laboratory, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Szucs+A%22">Szucs A</searchLink>; Neuronal Cell Biology Research Group, Eötvös Loránd University, Budapest, Hungary.<br /><searchLink fieldCode="AU" term="%22Lamsa+K%22">Lamsa K</searchLink>; Hungarian Center of Excellence for Molecular Medicine Research Group for Human Neuron Physiology and Therapy, Szeged, Hungary.; Department of Physiology, Anatomy and Neuroscience, University of Szeged, Szeged, Hungary.
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  Data: <searchLink fieldCode="JN" term="%22101183755%22">PLoS biology</searchLink> [PLoS Biol] 2025 Dec 10; Vol. 23 (12), pp. e3003549. <i>Date of Electronic Publication: </i>2025 Dec 10 (<i>Print Publication: </i>2025).
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