Potentiation of ryanodine receptor-mediated calcium release by MAPK is responsible for epidermal transformation and carcinogenesis.

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Title: Potentiation of ryanodine receptor-mediated calcium release by MAPK is responsible for epidermal transformation and carcinogenesis.
Authors: Wang P; Department of Biotechnology and Pharmaceutical Sciences, College of Pharmacy, Western University of Health Sciences, Pomona, CA 91766.; Department of Stomatology, Beijing Chaoyang Hospital, Capital Medical University, Beijing 100020, China., Cleveland KH; Department of Biotechnology and Pharmaceutical Sciences, College of Pharmacy, Western University of Health Sciences, Pomona, CA 91766., Shahid A; Department of Biotechnology and Pharmaceutical Sciences, College of Pharmacy, Western University of Health Sciences, Pomona, CA 91766., Rathnayaka C; Department of Biotechnology and Pharmaceutical Sciences, College of Pharmacy, Western University of Health Sciences, Pomona, CA 91766., Amirrad F; Department of Pharmaceutical Sciences, Marshall B. Ketchum University, Fullerton, CA 92831.; Department of Biomedical and Pharmaceutical Sciences, Chapman University School of Pharmacy, Irvine, CA 92618., Song Z; Libin Cardiovascular Institute, Department of Physiology and Pharmacology, Cumming School of Medicine, University of Calgary, Calgary, AB T2N 4N1, Canada., Estillore JP; Libin Cardiovascular Institute, Department of Physiology and Pharmacology, Cumming School of Medicine, University of Calgary, Calgary, AB T2N 4N1, Canada., Wang R; Libin Cardiovascular Institute, Department of Physiology and Pharmacology, Cumming School of Medicine, University of Calgary, Calgary, AB T2N 4N1, Canada., Back TG; Department of Chemistry, University of Calgary, Calgary, AB T2N 1N4, Canada., Chen SRW; Libin Cardiovascular Institute, Department of Physiology and Pharmacology, Cumming School of Medicine, University of Calgary, Calgary, AB T2N 4N1, Canada., Huang Y; Department of Biotechnology and Pharmaceutical Sciences, College of Pharmacy, Western University of Health Sciences, Pomona, CA 91766.
Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2025 Dec 16; Vol. 122 (50), pp. e2505055122. Date of Electronic Publication: 2025 Dec 10.
Publication Type: Journal Article
Journal Info: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1091-6490 (Electronic) Linking ISSN: 00278424 NLM ISO Abbreviation: Proc Natl Acad Sci U S A Subsets: MEDLINE
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  Data: Potentiation of ryanodine receptor-mediated calcium release by MAPK is responsible for epidermal transformation and carcinogenesis.
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  Data: <searchLink fieldCode="AU" term="%22Wang+P%22">Wang P</searchLink>; Department of Biotechnology and Pharmaceutical Sciences, College of Pharmacy, Western University of Health Sciences, Pomona, CA 91766.; Department of Stomatology, Beijing Chaoyang Hospital, Capital Medical University, Beijing 100020, China.<br /><searchLink fieldCode="AU" term="%22Cleveland+KH%22">Cleveland KH</searchLink>; Department of Biotechnology and Pharmaceutical Sciences, College of Pharmacy, Western University of Health Sciences, Pomona, CA 91766.<br /><searchLink fieldCode="AU" term="%22Shahid+A%22">Shahid A</searchLink>; Department of Biotechnology and Pharmaceutical Sciences, College of Pharmacy, Western University of Health Sciences, Pomona, CA 91766.<br /><searchLink fieldCode="AU" term="%22Rathnayaka+C%22">Rathnayaka C</searchLink>; Department of Biotechnology and Pharmaceutical Sciences, College of Pharmacy, Western University of Health Sciences, Pomona, CA 91766.<br /><searchLink fieldCode="AU" term="%22Amirrad+F%22">Amirrad F</searchLink>; Department of Pharmaceutical Sciences, Marshall B. Ketchum University, Fullerton, CA 92831.; Department of Biomedical and Pharmaceutical Sciences, Chapman University School of Pharmacy, Irvine, CA 92618.<br /><searchLink fieldCode="AU" term="%22Song+Z%22">Song Z</searchLink>; Libin Cardiovascular Institute, Department of Physiology and Pharmacology, Cumming School of Medicine, University of Calgary, Calgary, AB T2N 4N1, Canada.<br /><searchLink fieldCode="AU" term="%22Estillore+JP%22">Estillore JP</searchLink>; Libin Cardiovascular Institute, Department of Physiology and Pharmacology, Cumming School of Medicine, University of Calgary, Calgary, AB T2N 4N1, Canada.<br /><searchLink fieldCode="AU" term="%22Wang+R%22">Wang R</searchLink>; Libin Cardiovascular Institute, Department of Physiology and Pharmacology, Cumming School of Medicine, University of Calgary, Calgary, AB T2N 4N1, Canada.<br /><searchLink fieldCode="AU" term="%22Back+TG%22">Back TG</searchLink>; Department of Chemistry, University of Calgary, Calgary, AB T2N 1N4, Canada.<br /><searchLink fieldCode="AU" term="%22Chen+SRW%22">Chen SRW</searchLink>; Libin Cardiovascular Institute, Department of Physiology and Pharmacology, Cumming School of Medicine, University of Calgary, Calgary, AB T2N 4N1, Canada.<br /><searchLink fieldCode="AU" term="%22Huang+Y%22">Huang Y</searchLink>; Department of Biotechnology and Pharmaceutical Sciences, College of Pharmacy, Western University of Health Sciences, Pomona, CA 91766.
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  Data: <searchLink fieldCode="JN" term="%227505876%22">Proceedings of the National Academy of Sciences of the United States of America</searchLink> [Proc Natl Acad Sci U S A] 2025 Dec 16; Vol. 122 (50), pp. e2505055122. <i>Date of Electronic Publication: </i>2025 Dec 10.
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              Text: 2025 Dec 16
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