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Radix Aucklandiae inhibits M1 macrophage polarization to alleviate ulcerative colitis by modulating gut microbial production of indole-3-aldehyde.

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Title: Radix Aucklandiae inhibits M1 macrophage polarization to alleviate ulcerative colitis by modulating gut microbial production of indole-3-aldehyde.
Authors: Tang WY; Guangdong Provincial Key Laboratory of Chinese Medicine Pharmaceutics, School of Traditional Chinese Medicine, Southern Medical University, Guangzhou 510515, PR China; Guangdong Basic Research Center of Excellence for Integrated Traditional and Western Medicine for Qingzhi Diseases, Guangzhou 510515, PR China., Zhang JX; Guangdong Provincial Key Laboratory of Chinese Medicine Pharmaceutics, School of Traditional Chinese Medicine, Southern Medical University, Guangzhou 510515, PR China; Guangdong Basic Research Center of Excellence for Integrated Traditional and Western Medicine for Qingzhi Diseases, Guangzhou 510515, PR China., Hu YX; Department of Gastroenterology, PLA General Hospital of Southern Theater Command, Guangzhou 510010, PR China., Chen ZZ; School of Clinical Medicine, Guangdong Pharmaceutical University, Guangzhou 510006, PR China., Zhang Y; Department of Pharmacology and Toxicology, University of Toronto, Toronto, Ontario, Canada., Dong SQ; Guangdong Provincial Key Laboratory of Chinese Medicine Pharmaceutics, School of Traditional Chinese Medicine, Southern Medical University, Guangzhou 510515, PR China., Xie YR; Guangdong Provincial Key Laboratory of Chinese Medicine Pharmaceutics, School of Traditional Chinese Medicine, Southern Medical University, Guangzhou 510515, PR China., Wang HZ; Guangdong Provincial Key Laboratory of Chinese Medicine Pharmaceutics, School of Traditional Chinese Medicine, Southern Medical University, Guangzhou 510515, PR China., Liang JQ; Guangdong Provincial Key Laboratory of Chinese Medicine Pharmaceutics, School of Traditional Chinese Medicine, Southern Medical University, Guangzhou 510515, PR China., Li Y; Endoscopy center, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Southern Medical University, Guangzhou 510080, China., Tan XM; Guangdong Provincial Key Laboratory of Chinese Medicine Pharmaceutics, School of Traditional Chinese Medicine, Southern Medical University, Guangzhou 510515, PR China. Electronic address: tanxm_smu@163.com., Wu ZY; Guangdong Provincial Key Laboratory of Chinese Medicine Pharmaceutics, School of Traditional Chinese Medicine, Southern Medical University, Guangzhou 510515, PR China; Guangdong Basic Research Center of Excellence for Integrated Traditional and Western Medicine for Qingzhi Diseases, Guangzhou 510515, PR China. Electronic address: 11100227@smu.edu.cn., Liu CS; Guangdong Provincial Key Laboratory of Chinese Medicine Pharmaceutics, School of Traditional Chinese Medicine, Southern Medical University, Guangzhou 510515, PR China; Guangdong Basic Research Center of Excellence for Integrated Traditional and Western Medicine for Qingzhi Diseases, Guangzhou 510515, PR China. Electronic address: lcshun1225@163.com.
Source: Phytomedicine : international journal of phytotherapy and phytopharmacology [Phytomedicine] 2026 Jan; Vol. 150, pp. 157659. Date of Electronic Publication: 2025 Dec 03.
Publication Type: Journal Article
Journal Info: Publisher: Urban & Fischer Verlag Country of Publication: Germany NLM ID: 9438794 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1618-095X (Electronic) Linking ISSN: 09447113 NLM ISO Abbreviation: Phytomedicine Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Radix Aucklandiae inhibits M1 macrophage polarization to alleviate ulcerative colitis by modulating gut microbial production of indole-3-aldehyde.
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  Data: <searchLink fieldCode="AU" term="%22Tang+WY%22">Tang WY</searchLink>; Guangdong Provincial Key Laboratory of Chinese Medicine Pharmaceutics, School of Traditional Chinese Medicine, Southern Medical University, Guangzhou 510515, PR China; Guangdong Basic Research Center of Excellence for Integrated Traditional and Western Medicine for Qingzhi Diseases, Guangzhou 510515, PR China.<br /><searchLink fieldCode="AU" term="%22Zhang+JX%22">Zhang JX</searchLink>; Guangdong Provincial Key Laboratory of Chinese Medicine Pharmaceutics, School of Traditional Chinese Medicine, Southern Medical University, Guangzhou 510515, PR China; Guangdong Basic Research Center of Excellence for Integrated Traditional and Western Medicine for Qingzhi Diseases, Guangzhou 510515, PR China.<br /><searchLink fieldCode="AU" term="%22Hu+YX%22">Hu YX</searchLink>; Department of Gastroenterology, PLA General Hospital of Southern Theater Command, Guangzhou 510010, PR China.<br /><searchLink fieldCode="AU" term="%22Chen+ZZ%22">Chen ZZ</searchLink>; School of Clinical Medicine, Guangdong Pharmaceutical University, Guangzhou 510006, PR China.<br /><searchLink fieldCode="AU" term="%22Zhang+Y%22">Zhang Y</searchLink>; Department of Pharmacology and Toxicology, University of Toronto, Toronto, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Dong+SQ%22">Dong SQ</searchLink>; Guangdong Provincial Key Laboratory of Chinese Medicine Pharmaceutics, School of Traditional Chinese Medicine, Southern Medical University, Guangzhou 510515, PR China.<br /><searchLink fieldCode="AU" term="%22Xie+YR%22">Xie YR</searchLink>; Guangdong Provincial Key Laboratory of Chinese Medicine Pharmaceutics, School of Traditional Chinese Medicine, Southern Medical University, Guangzhou 510515, PR China.<br /><searchLink fieldCode="AU" term="%22Wang+HZ%22">Wang HZ</searchLink>; Guangdong Provincial Key Laboratory of Chinese Medicine Pharmaceutics, School of Traditional Chinese Medicine, Southern Medical University, Guangzhou 510515, PR China.<br /><searchLink fieldCode="AU" term="%22Liang+JQ%22">Liang JQ</searchLink>; Guangdong Provincial Key Laboratory of Chinese Medicine Pharmaceutics, School of Traditional Chinese Medicine, Southern Medical University, Guangzhou 510515, PR China.<br /><searchLink fieldCode="AU" term="%22Li+Y%22">Li Y</searchLink>; Endoscopy center, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Southern Medical University, Guangzhou 510080, China.<br /><searchLink fieldCode="AU" term="%22Tan+XM%22">Tan XM</searchLink>; Guangdong Provincial Key Laboratory of Chinese Medicine Pharmaceutics, School of Traditional Chinese Medicine, Southern Medical University, Guangzhou 510515, PR China. Electronic address: tanxm_smu@163.com.<br /><searchLink fieldCode="AU" term="%22Wu+ZY%22">Wu ZY</searchLink>; Guangdong Provincial Key Laboratory of Chinese Medicine Pharmaceutics, School of Traditional Chinese Medicine, Southern Medical University, Guangzhou 510515, PR China; Guangdong Basic Research Center of Excellence for Integrated Traditional and Western Medicine for Qingzhi Diseases, Guangzhou 510515, PR China. Electronic address: 11100227@smu.edu.cn.<br /><searchLink fieldCode="AU" term="%22Liu+CS%22">Liu CS</searchLink>; Guangdong Provincial Key Laboratory of Chinese Medicine Pharmaceutics, School of Traditional Chinese Medicine, Southern Medical University, Guangzhou 510515, PR China; Guangdong Basic Research Center of Excellence for Integrated Traditional and Western Medicine for Qingzhi Diseases, Guangzhou 510515, PR China. Electronic address: lcshun1225@163.com.
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  Data: <searchLink fieldCode="JN" term="%229438794%22">Phytomedicine : international journal of phytotherapy and phytopharmacology</searchLink> [Phytomedicine] 2026 Jan; Vol. 150, pp. 157659. <i>Date of Electronic Publication: </i>2025 Dec 03.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Urban+%26+Fischer+Verlag%22">Urban & Fischer Verlag </searchLink><i>Country of Publication: </i>Germany <i>NLM ID: </i>9438794 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1618-095X (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2209447113%22">09447113 </searchLink><i>NLM ISO Abbreviation: </i>Phytomedicine <i>Subsets: </i>MEDLINE
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        Value: 10.1016/j.phymed.2025.157659
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        Text: English
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        StartPage: 157659
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      – TitleFull: Radix Aucklandiae inhibits M1 macrophage polarization to alleviate ulcerative colitis by modulating gut microbial production of indole-3-aldehyde.
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            – D: 01
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              Text: 2026 Jan
              Type: published
              Y: 2026
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