Erythropoietin receptor on cDC1s dictates immune tolerance.

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Title: Erythropoietin receptor on cDC1s dictates immune tolerance.
Authors: Zhang X; Department of Pathology, School of Medicine, Stanford University, Palo Alto, CA, USA. xiangyue@stanford.edu., McGinnis CS; Department of Pathology, School of Medicine, Stanford University, Palo Alto, CA, USA.; Parker Institute for Cancer Immunotherapy, San Francisco, CA, USA., Yu G; Department of Pathology, School of Medicine, Stanford University, Palo Alto, CA, USA., Chen S; Department of Genetics, School of Medicine, Stanford University, Palo Alto, CA, USA., Zheng P; Department of Medicine, Division of Blood and Marrow Transplantation and Cellular Therapy, School of Medicine, Stanford University, Palo Alto, CA, USA., Schürch CM; Department of Pathology and Neuropathology, University Hospital and Comprehensive Cancer Center Tübingen, Tübingen, Germany.; Cluster of Excellence iFIT (EXC 2180), Image-Guided and Functionally Instructed Tumor Therapies, University of Tübingen, Tübingen, Germany., Hiam-Galvez KJ; Department of Pathology, School of Medicine, Stanford University, Palo Alto, CA, USA., Reticker-Flynn NE; Department of Otolaryngology-Head and Neck Surgery, School of Medicine, Stanford University, Stanford, CA, USA., Guo W; Department of Pathology, School of Medicine, Stanford University, Palo Alto, CA, USA., Yao W; Department of Pathology, School of Medicine, Stanford University, Palo Alto, CA, USA., Qiu J; Department of Pathology, School of Medicine, Stanford University, Palo Alto, CA, USA., Muselman A; Department of Pathology, School of Medicine, Stanford University, Palo Alto, CA, USA., Linde IL; Department of Pathology, School of Medicine, Stanford University, Palo Alto, CA, USA., Hickey JW; Department of Biomedical Engineering, Duke University, Durham, NC, USA., Yan H; Department of Medicine, Division of Blood and Marrow Transplantation and Cellular Therapy, School of Medicine, Stanford University, Palo Alto, CA, USA., Tran VM; Department of Dermatology, University of California, San Francisco, San Francisco, CA, USA., Qiu W; Division of Pulmonary, Critical Care, Allergy and Sleep, Department of Medicine, University of California, San Francisco, San Francisco, CA, USA., Brichart-Vernos D; CIRI, Centre International de Recherche en Infectiologie, Université de Lyon, Inserm U1111, Université Claude Bernard Lyon 1, CNRS UMR5308, ENS de Lyon, Lyon, France., Hirai T; Department of Medicine, Division of Blood and Marrow Transplantation and Cellular Therapy, School of Medicine, Stanford University, Palo Alto, CA, USA., Yu B; ImmunEdge, Redwood City, CA, USA., An X; Laboratory of Membrane Biology, New York Blood Center, New York, NY, USA., Xiao Y; Department of Immunology, Leiden University Medical Center, Leiden, The Netherlands., Paidassi H; CIRI, Centre International de Recherche en Infectiologie, Université de Lyon, Inserm U1111, Université Claude Bernard Lyon 1, CNRS UMR5308, ENS de Lyon, Lyon, France., Scharschmidt TC; Department of Dermatology, University of California, San Francisco, San Francisco, CA, USA., Angelo M; Department of Pathology, School of Medicine, Stanford University, Palo Alto, CA, USA., Sheppard D; Division of Pulmonary, Critical Care, Allergy and Sleep, Department of Medicine, University of California, San Francisco, San Francisco, CA, USA., Chi H; Department of Immunology, St Jude Children's Research Hospital, Memphis, TN, USA., Satpathy AT; Department of Pathology, School of Medicine, Stanford University, Palo Alto, CA, USA.; Parker Institute for Cancer Immunotherapy, San Francisco, CA, USA., Way SS; Division of Infectious Diseases, Center for Inflammation and Tolerance, Cincinnati Children's Hospital Medical Center, Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, USA., Malissen B; Centre d'Immunologie de Marseille-Luminy, Aix-Marseille Université, INSERM, CNRS, Marseille, France., Strober S; Department of Medicine (Immunology and Rheumatology), School of Medicine, Stanford University, Palo Alto, CA, USA., Engleman EG; Department of Pathology, School of Medicine, Stanford University, Palo Alto, CA, USA. edgareng@stanford.edu.; Stanford Cancer Institute, School of Medicine, Stanford University, Palo Alto, CA, USA. edgareng@stanford.edu.
Source: Nature [Nature] 2026 Feb; Vol. 650 (8101), pp. 470-480. Date of Electronic Publication: 2025 Dec 10.
Publication Type: Journal Article; Research Support, N.I.H., Extramural
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4687 (Electronic) Linking ISSN: 00280836 NLM ISO Abbreviation: Nature Subsets: MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22Zhang+X%22">Zhang X</searchLink>; Department of Pathology, School of Medicine, Stanford University, Palo Alto, CA, USA. xiangyue@stanford.edu.<br /><searchLink fieldCode="AU" term="%22McGinnis+CS%22">McGinnis CS</searchLink>; Department of Pathology, School of Medicine, Stanford University, Palo Alto, CA, USA.; Parker Institute for Cancer Immunotherapy, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Yu+G%22">Yu G</searchLink>; Department of Pathology, School of Medicine, Stanford University, Palo Alto, CA, USA.<br /><searchLink fieldCode="AU" term="%22Chen+S%22">Chen S</searchLink>; Department of Genetics, School of Medicine, Stanford University, Palo Alto, CA, USA.<br /><searchLink fieldCode="AU" term="%22Zheng+P%22">Zheng P</searchLink>; Department of Medicine, Division of Blood and Marrow Transplantation and Cellular Therapy, School of Medicine, Stanford University, Palo Alto, CA, USA.<br /><searchLink fieldCode="AU" term="%22Schürch+CM%22">Schürch CM</searchLink>; Department of Pathology and Neuropathology, University Hospital and Comprehensive Cancer Center Tübingen, Tübingen, Germany.; Cluster of Excellence iFIT (EXC 2180), Image-Guided and Functionally Instructed Tumor Therapies, University of Tübingen, Tübingen, Germany.<br /><searchLink fieldCode="AU" term="%22Hiam-Galvez+KJ%22">Hiam-Galvez KJ</searchLink>; Department of Pathology, School of Medicine, Stanford University, Palo Alto, CA, USA.<br /><searchLink fieldCode="AU" term="%22Reticker-Flynn+NE%22">Reticker-Flynn NE</searchLink>; Department of Otolaryngology-Head and Neck Surgery, School of Medicine, Stanford University, Stanford, CA, USA.<br /><searchLink fieldCode="AU" term="%22Guo+W%22">Guo W</searchLink>; Department of Pathology, School of Medicine, Stanford University, Palo Alto, CA, USA.<br /><searchLink fieldCode="AU" term="%22Yao+W%22">Yao W</searchLink>; Department of Pathology, School of Medicine, Stanford University, Palo Alto, CA, USA.<br /><searchLink fieldCode="AU" term="%22Qiu+J%22">Qiu J</searchLink>; Department of Pathology, School of Medicine, Stanford University, Palo Alto, CA, USA.<br /><searchLink fieldCode="AU" term="%22Muselman+A%22">Muselman A</searchLink>; Department of Pathology, School of Medicine, Stanford University, Palo Alto, CA, USA.<br /><searchLink fieldCode="AU" term="%22Linde+IL%22">Linde IL</searchLink>; Department of Pathology, School of Medicine, Stanford University, Palo Alto, CA, USA.<br /><searchLink fieldCode="AU" term="%22Hickey+JW%22">Hickey JW</searchLink>; Department of Biomedical Engineering, Duke University, Durham, NC, USA.<br /><searchLink fieldCode="AU" term="%22Yan+H%22">Yan H</searchLink>; Department of Medicine, Division of Blood and Marrow Transplantation and Cellular Therapy, School of Medicine, Stanford University, Palo Alto, CA, USA.<br /><searchLink fieldCode="AU" term="%22Tran+VM%22">Tran VM</searchLink>; Department of Dermatology, University of California, San Francisco, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Qiu+W%22">Qiu W</searchLink>; Division of Pulmonary, Critical Care, Allergy and Sleep, Department of Medicine, University of California, San Francisco, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Brichart-Vernos+D%22">Brichart-Vernos D</searchLink>; CIRI, Centre International de Recherche en Infectiologie, Université de Lyon, Inserm U1111, Université Claude Bernard Lyon 1, CNRS UMR5308, ENS de Lyon, Lyon, France.<br /><searchLink fieldCode="AU" term="%22Hirai+T%22">Hirai T</searchLink>; Department of Medicine, Division of Blood and Marrow Transplantation and Cellular Therapy, School of Medicine, Stanford University, Palo Alto, CA, USA.<br /><searchLink fieldCode="AU" term="%22Yu+B%22">Yu B</searchLink>; ImmunEdge, Redwood City, CA, USA.<br /><searchLink fieldCode="AU" term="%22An+X%22">An X</searchLink>; Laboratory of Membrane Biology, New York Blood Center, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Xiao+Y%22">Xiao Y</searchLink>; Department of Immunology, Leiden University Medical Center, Leiden, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Paidassi+H%22">Paidassi H</searchLink>; CIRI, Centre International de Recherche en Infectiologie, Université de Lyon, Inserm U1111, Université Claude Bernard Lyon 1, CNRS UMR5308, ENS de Lyon, Lyon, France.<br /><searchLink fieldCode="AU" term="%22Scharschmidt+TC%22">Scharschmidt TC</searchLink>; Department of Dermatology, University of California, San Francisco, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Angelo+M%22">Angelo M</searchLink>; Department of Pathology, School of Medicine, Stanford University, Palo Alto, CA, USA.<br /><searchLink fieldCode="AU" term="%22Sheppard+D%22">Sheppard D</searchLink>; Division of Pulmonary, Critical Care, Allergy and Sleep, Department of Medicine, University of California, San Francisco, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Chi+H%22">Chi H</searchLink>; Department of Immunology, St Jude Children's Research Hospital, Memphis, TN, USA.<br /><searchLink fieldCode="AU" term="%22Satpathy+AT%22">Satpathy AT</searchLink>; Department of Pathology, School of Medicine, Stanford University, Palo Alto, CA, USA.; Parker Institute for Cancer Immunotherapy, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Way+SS%22">Way SS</searchLink>; Division of Infectious Diseases, Center for Inflammation and Tolerance, Cincinnati Children's Hospital Medical Center, Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, USA.<br /><searchLink fieldCode="AU" term="%22Malissen+B%22">Malissen B</searchLink>; Centre d'Immunologie de Marseille-Luminy, Aix-Marseille Université, INSERM, CNRS, Marseille, France.<br /><searchLink fieldCode="AU" term="%22Strober+S%22">Strober S</searchLink>; Department of Medicine (Immunology and Rheumatology), School of Medicine, Stanford University, Palo Alto, CA, USA.<br /><searchLink fieldCode="AU" term="%22Engleman+EG%22">Engleman EG</searchLink>; Department of Pathology, School of Medicine, Stanford University, Palo Alto, CA, USA. edgareng@stanford.edu.; Stanford Cancer Institute, School of Medicine, Stanford University, Palo Alto, CA, USA. edgareng@stanford.edu.
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