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Decreased cytoplasmic crowding via inhibition of ribosome biogenesis can trigger Candida albicans filamentous growth.

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Title: Decreased cytoplasmic crowding via inhibition of ribosome biogenesis can trigger Candida albicans filamentous growth.
Authors: Serrano A; Université Côte d'Azur, CNRS, INSERM, Institute of Biology Valrose (iBV), Nice, France.; Centro de Biotecnología y Genómica de Plantas, Universidad Politécnica de Madrid (UPM)-Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria (INIA/CSIC), Pozuelo de Alarcón, Spain., Puerner C; Université Côte d'Azur, CNRS, INSERM, Institute of Biology Valrose (iBV), Nice, France.; Department of Microbiology and Immunology, Geisel School of Medicine at Dartmouth, Hanover, NH, USA., Chevalier L; Université Côte d'Azur, CNRS, INSERM, Institute of Biology Valrose (iBV), Nice, France., Plumb E; Université Côte d'Azur, CNRS, INSERM, Institute of Biology Valrose (iBV), Nice, France., Elferich J; RNA Therapeutics Institute, University of Massachusetts Chan Medical School, Worcester, MA, USA.; Howard Hughes Medical Institute, University of Massachusetts Chan Medical School, Worcester, MA, USA., Diggs S; RNA Therapeutics Institute, University of Massachusetts Chan Medical School, Worcester, MA, USA., Sinn LR; Department of Biochemistry, Charité-Universitätsmedizin Berlin, Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany., Grigorieff N; RNA Therapeutics Institute, University of Massachusetts Chan Medical School, Worcester, MA, USA.; Howard Hughes Medical Institute, University of Massachusetts Chan Medical School, Worcester, MA, USA., Ralser M; Department of Biochemistry, Charité-Universitätsmedizin Berlin, Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.; Berlin Institute of Health (BIH) at Charité-Universitätsmedizin Berlin, Berlin, Germany.; Max Planck Institute for Molecular Genetics, Berlin, Germany., Delarue M; LAAS-CNRS, University of Toulouse, CNRS, Toulouse, France., Bassilana M; Université Côte d'Azur, CNRS, INSERM, Institute of Biology Valrose (iBV), Nice, France., Arkowitz RA; Université Côte d'Azur, CNRS, INSERM, Institute of Biology Valrose (iBV), Nice, France. Robert.Arkowitz@univ-cotedazur.fr.
Source: Nature microbiology [Nat Microbiol] 2026 Jan; Vol. 11 (1), pp. 169-179. Date of Electronic Publication: 2025 Dec 10.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101674869 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2058-5276 (Electronic) Linking ISSN: 20585276 NLM ISO Abbreviation: Nat Microbiol Subsets: MEDLINE
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  Data: Decreased cytoplasmic crowding via inhibition of ribosome biogenesis can trigger Candida albicans filamentous growth.
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  Data: <searchLink fieldCode="AU" term="%22Serrano+A%22">Serrano A</searchLink>; Université Côte d'Azur, CNRS, INSERM, Institute of Biology Valrose (iBV), Nice, France.; Centro de Biotecnología y Genómica de Plantas, Universidad Politécnica de Madrid (UPM)-Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria (INIA/CSIC), Pozuelo de Alarcón, Spain.<br /><searchLink fieldCode="AU" term="%22Puerner+C%22">Puerner C</searchLink>; Université Côte d'Azur, CNRS, INSERM, Institute of Biology Valrose (iBV), Nice, France.; Department of Microbiology and Immunology, Geisel School of Medicine at Dartmouth, Hanover, NH, USA.<br /><searchLink fieldCode="AU" term="%22Chevalier+L%22">Chevalier L</searchLink>; Université Côte d'Azur, CNRS, INSERM, Institute of Biology Valrose (iBV), Nice, France.<br /><searchLink fieldCode="AU" term="%22Plumb+E%22">Plumb E</searchLink>; Université Côte d'Azur, CNRS, INSERM, Institute of Biology Valrose (iBV), Nice, France.<br /><searchLink fieldCode="AU" term="%22Elferich+J%22">Elferich J</searchLink>; RNA Therapeutics Institute, University of Massachusetts Chan Medical School, Worcester, MA, USA.; Howard Hughes Medical Institute, University of Massachusetts Chan Medical School, Worcester, MA, USA.<br /><searchLink fieldCode="AU" term="%22Diggs+S%22">Diggs S</searchLink>; RNA Therapeutics Institute, University of Massachusetts Chan Medical School, Worcester, MA, USA.<br /><searchLink fieldCode="AU" term="%22Sinn+LR%22">Sinn LR</searchLink>; Department of Biochemistry, Charité-Universitätsmedizin Berlin, Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Grigorieff+N%22">Grigorieff N</searchLink>; RNA Therapeutics Institute, University of Massachusetts Chan Medical School, Worcester, MA, USA.; Howard Hughes Medical Institute, University of Massachusetts Chan Medical School, Worcester, MA, USA.<br /><searchLink fieldCode="AU" term="%22Ralser+M%22">Ralser M</searchLink>; Department of Biochemistry, Charité-Universitätsmedizin Berlin, Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.; Berlin Institute of Health (BIH) at Charité-Universitätsmedizin Berlin, Berlin, Germany.; Max Planck Institute for Molecular Genetics, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Delarue+M%22">Delarue M</searchLink>; LAAS-CNRS, University of Toulouse, CNRS, Toulouse, France.<br /><searchLink fieldCode="AU" term="%22Bassilana+M%22">Bassilana M</searchLink>; Université Côte d'Azur, CNRS, INSERM, Institute of Biology Valrose (iBV), Nice, France.<br /><searchLink fieldCode="AU" term="%22Arkowitz+RA%22">Arkowitz RA</searchLink>; Université Côte d'Azur, CNRS, INSERM, Institute of Biology Valrose (iBV), Nice, France. Robert.Arkowitz@univ-cotedazur.fr.
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