HLA-haploidentical hematopoietic stem cell transplantation in patients with sickle cell disease: results from the phase II DREP-HAPLO trial.

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Title: HLA-haploidentical hematopoietic stem cell transplantation in patients with sickle cell disease: results from the phase II DREP-HAPLO trial.
Authors: Dhedin N; Adolescent and Young Adult Hematology Unit, Saint Louis University Hospital, Assistance Publique-Hopitaux de Paris (AP-HP), Paris, France; Epidemiology and Clinical Statistics for Trials and Real-world evidence Research (ECSTRRA), Saint Louis Research Institute, UMR1342, INSERM, Universite de Paris. nathalie.dhedin@aphp.fr., Bruno B; Paediatric Hematology, F-59000 Lille., Paillard C; Department of Paediatric Haematology and Oncology, Strasbourg University Hospital, Strasbourg, France; Strasbourg University, INSERM, IRM UMR-S 1109, F-67000 Strasbourg., Gounfle E; Department of Health Research and Innovation, Intercommunal Hospital Center of Creteil, Creteil., Buchbinder N; Department of Paediatric Haematology and Oncology, Charles Nicolle University Hospital, Rouen., Chardin MO; Institute of Pediatric Oncology and Hematology, Lyon., Gaba M; Department of Health Research and Innovation, Intercommunal Hospital Center of Creteil, Creteil., Arlet JB; French Sickle Cell Referral Center, Internal Medicine Department, Georges Pompidou European Hospital, and Paris University, Paris., Arnaud C; Pediatric department Sickle Cell Referral Center, Centre Hospitalier Intercommunal de Creteil., Jung C; Department of Health Research and Innovation, Intercommunal Hospital Center of Creteil, Creteil, France; Pediatric department Intercommunal Hospital Center of Creteil and University Paris-Est Creteil, Creteil., Pondarre C; Intercommunal Hospital Center of Creteil, INSERM U955, IMRB, Paris XII University, Creteil.
Source: Haematologica [Haematologica] 2026 Jul 01; Vol. 111 (7), pp. 2377-2384. Date of Electronic Publication: 2025 Dec 11.
Publication Type: Journal Article; Clinical Trial, Phase II; Multicenter Study
Journal Info: Publisher: Ferrata Storti Foundation Country of Publication: Italy NLM ID: 0417435 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1592-8721 (Electronic) Linking ISSN: 03906078 NLM ISO Abbreviation: Haematologica Subsets: MEDLINE
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  Data: HLA-haploidentical hematopoietic stem cell transplantation in patients with sickle cell disease: results from the phase II DREP-HAPLO trial.
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  Data: <searchLink fieldCode="AU" term="%22Dhedin+N%22">Dhedin N</searchLink>; Adolescent and Young Adult Hematology Unit, Saint Louis University Hospital, Assistance Publique-Hopitaux de Paris (AP-HP), Paris, France; Epidemiology and Clinical Statistics for Trials and Real-world evidence Research (ECSTRRA), Saint Louis Research Institute, UMR1342, INSERM, Universite de Paris. nathalie.dhedin@aphp.fr.<br /><searchLink fieldCode="AU" term="%22Bruno+B%22">Bruno B</searchLink>; Paediatric Hematology, F-59000 Lille.<br /><searchLink fieldCode="AU" term="%22Paillard+C%22">Paillard C</searchLink>; Department of Paediatric Haematology and Oncology, Strasbourg University Hospital, Strasbourg, France; Strasbourg University, INSERM, IRM UMR-S 1109, F-67000 Strasbourg.<br /><searchLink fieldCode="AU" term="%22Gounfle+E%22">Gounfle E</searchLink>; Department of Health Research and Innovation, Intercommunal Hospital Center of Creteil, Creteil.<br /><searchLink fieldCode="AU" term="%22Buchbinder+N%22">Buchbinder N</searchLink>; Department of Paediatric Haematology and Oncology, Charles Nicolle University Hospital, Rouen.<br /><searchLink fieldCode="AU" term="%22Chardin+MO%22">Chardin MO</searchLink>; Institute of Pediatric Oncology and Hematology, Lyon.<br /><searchLink fieldCode="AU" term="%22Gaba+M%22">Gaba M</searchLink>; Department of Health Research and Innovation, Intercommunal Hospital Center of Creteil, Creteil.<br /><searchLink fieldCode="AU" term="%22Arlet+JB%22">Arlet JB</searchLink>; French Sickle Cell Referral Center, Internal Medicine Department, Georges Pompidou European Hospital, and Paris University, Paris.<br /><searchLink fieldCode="AU" term="%22Arnaud+C%22">Arnaud C</searchLink>; Pediatric department Sickle Cell Referral Center, Centre Hospitalier Intercommunal de Creteil.<br /><searchLink fieldCode="AU" term="%22Jung+C%22">Jung C</searchLink>; Department of Health Research and Innovation, Intercommunal Hospital Center of Creteil, Creteil, France; Pediatric department Intercommunal Hospital Center of Creteil and University Paris-Est Creteil, Creteil.<br /><searchLink fieldCode="AU" term="%22Pondarre+C%22">Pondarre C</searchLink>; Intercommunal Hospital Center of Creteil, INSERM U955, IMRB, Paris XII University, Creteil.
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  Data: <searchLink fieldCode="JN" term="%220417435%22">Haematologica</searchLink> [Haematologica] 2026 Jul 01; Vol. 111 (7), pp. 2377-2384. <i>Date of Electronic Publication: </i>2025 Dec 11.
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  Data: Journal Article; Clinical Trial, Phase II; Multicenter Study
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Ferrata+Storti+Foundation%22">Ferrata Storti Foundation </searchLink><i>Country of Publication: </i>Italy <i>NLM ID: </i>0417435 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1592-8721 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2203906078%22">03906078 </searchLink><i>NLM ISO Abbreviation: </i>Haematologica <i>Subsets: </i>MEDLINE
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        Value: 10.3324/haematol.2025.300013
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              Text: 2026 Jul 01
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