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Increased Cardiovascular Risk With Lorlatinib in Patients With ALK-Mutated Lung Cancer: A Real-World Comparative Study.

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Title: Increased Cardiovascular Risk With Lorlatinib in Patients With ALK-Mutated Lung Cancer: A Real-World Comparative Study.
Authors: Lin CY; Institute of Clinical Medicine, College of Medicine National Cheng Kung University Tainan Taiwan.; Department of Internal Medicine National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University Tainan Taiwan., Su PL; Department of Internal Medicine National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University Tainan Taiwan.; Division of Medical Oncology, Department of Internal Medicine The Ohio State University Comprehensive Cancer Center Columbus OH., Kuo CW; Institute of Clinical Medicine, College of Medicine National Cheng Kung University Tainan Taiwan.; Department of Internal Medicine National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University Tainan Taiwan., Tsai IL; Department of Internal Medicine National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University Tainan Taiwan., Liu TH; Department of Psychiatry Chi Mei Medical Center Tainan Taiwan., Yang J; Department of Medical Imaging National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University Tainan Taiwan., Lin CC; Institute of Clinical Medicine, College of Medicine National Cheng Kung University Tainan Taiwan.; Department of Internal Medicine National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University Tainan Taiwan.; Institute of Molecular Medicine, College of Medicine National Cheng Kung University Tainan 701 Taiwan.; Tainan Hospital, Ministry of Health & Welfare Tainan 701 Taiwan., Lin SH; Institute of Clinical Medicine, College of Medicine National Cheng Kung University Tainan Taiwan.; Biostatistics Consulting Center National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University Tainan Taiwan.; Department of Public Health, College of Medicine National Cheng Kung University Tainan Taiwan.
Source: Journal of the American Heart Association [J Am Heart Assoc] 2025 Dec 16; Vol. 14 (24), pp. e043620. Date of Electronic Publication: 2025 Dec 11.
Publication Type: Journal Article; Comparative Study
Journal Info: Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 101580524 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2047-9980 (Electronic) Linking ISSN: 20479980 NLM ISO Abbreviation: J Am Heart Assoc Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Increased Cardiovascular Risk With Lorlatinib in Patients With ALK-Mutated Lung Cancer: A Real-World Comparative Study.
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  Data: <searchLink fieldCode="AU" term="%22Lin+CY%22">Lin CY</searchLink>; Institute of Clinical Medicine, College of Medicine National Cheng Kung University Tainan Taiwan.; Department of Internal Medicine National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University Tainan Taiwan.<br /><searchLink fieldCode="AU" term="%22Su+PL%22">Su PL</searchLink>; Department of Internal Medicine National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University Tainan Taiwan.; Division of Medical Oncology, Department of Internal Medicine The Ohio State University Comprehensive Cancer Center Columbus OH.<br /><searchLink fieldCode="AU" term="%22Kuo+CW%22">Kuo CW</searchLink>; Institute of Clinical Medicine, College of Medicine National Cheng Kung University Tainan Taiwan.; Department of Internal Medicine National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University Tainan Taiwan.<br /><searchLink fieldCode="AU" term="%22Tsai+IL%22">Tsai IL</searchLink>; Department of Internal Medicine National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University Tainan Taiwan.<br /><searchLink fieldCode="AU" term="%22Liu+TH%22">Liu TH</searchLink>; Department of Psychiatry Chi Mei Medical Center Tainan Taiwan.<br /><searchLink fieldCode="AU" term="%22Yang+J%22">Yang J</searchLink>; Department of Medical Imaging National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University Tainan Taiwan.<br /><searchLink fieldCode="AU" term="%22Lin+CC%22">Lin CC</searchLink>; Institute of Clinical Medicine, College of Medicine National Cheng Kung University Tainan Taiwan.; Department of Internal Medicine National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University Tainan Taiwan.; Institute of Molecular Medicine, College of Medicine National Cheng Kung University Tainan 701 Taiwan.; Tainan Hospital, Ministry of Health & Welfare Tainan 701 Taiwan.<br /><searchLink fieldCode="AU" term="%22Lin+SH%22">Lin SH</searchLink>; Institute of Clinical Medicine, College of Medicine National Cheng Kung University Tainan Taiwan.; Biostatistics Consulting Center National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University Tainan Taiwan.; Department of Public Health, College of Medicine National Cheng Kung University Tainan Taiwan.
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  Data: <searchLink fieldCode="JN" term="%22101580524%22">Journal of the American Heart Association</searchLink> [J Am Heart Assoc] 2025 Dec 16; Vol. 14 (24), pp. e043620. <i>Date of Electronic Publication: </i>2025 Dec 11.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Wiley-Blackwell%22">Wiley-Blackwell </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101580524 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2047-9980 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2220479980%22">20479980 </searchLink><i>NLM ISO Abbreviation: </i>J Am Heart Assoc <i>Subsets: </i>MEDLINE
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        Value: 10.1161/JAHA.125.043620
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        Text: English
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      – TitleFull: Increased Cardiovascular Risk With Lorlatinib in Patients With ALK-Mutated Lung Cancer: A Real-World Comparative Study.
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            NameFull: Lin CC
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            – D: 16
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              Text: 2025 Dec 16
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              Y: 2025
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