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The aged amygdala's unique sensitivity to refined diets, independent of fat or sugar content: A brain region and cell type-specific analysis.

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Title: The aged amygdala's unique sensitivity to refined diets, independent of fat or sugar content: A brain region and cell type-specific analysis.
Authors: Butler MJ; Institute of Brain, Behavior, and Immunology, The Ohio State University, Columbus, OH, USA., Blackwell JA; Institute of Brain, Behavior, and Immunology, The Ohio State University, Columbus, OH, USA., Sanchez AA; Institute of Brain, Behavior, and Immunology, The Ohio State University, Columbus, OH, USA., Sanders HF; Department of Physiology and Cell Biology, Dorothy M. Davis Heart and Lung Research Institute, The Ohio State University Wexner Medical Center, Columbus, OH, USA., Kolonay DW; Department of Physiology and Cell Biology, Dorothy M. Davis Heart and Lung Research Institute, The Ohio State University Wexner Medical Center, Columbus, OH, USA., Jantsch J; Institute of Brain, Behavior, and Immunology, The Ohio State University, Columbus, OH, USA; Graduate Program in Biosciences, Federal University of Health Sciences of Porto Alegre, Porto Alegre, Rio Grande do Sul, Brazil., Muscat SM; Institute of Brain, Behavior, and Immunology, The Ohio State University, Columbus, OH, USA., Caetano-Silva ME; Department of Health and Kinesiology, University of Illinois Urbana-Champaign, Urbana, IL, USA., Shrestha A; Department of Health and Kinesiology, University of Illinois Urbana-Champaign, Urbana, IL, USA., Yun Lim CK; Department of Health and Kinesiology, University of Illinois Urbana-Champaign, Urbana, IL, USA., Mackey-Alfonso SE; Institute of Brain, Behavior, and Immunology, The Ohio State University, Columbus, OH, USA., Alvarez BD; Institute of Brain, Behavior, and Immunology, The Ohio State University, Columbus, OH, USA., McCusker RH; Department of Health and Kinesiology, University of Illinois Urbana-Champaign, Urbana, IL, USA., Allen JM; Department of Health and Kinesiology, University of Illinois Urbana-Champaign, Urbana, IL, USA., Baskin KK; Department of Physiology and Cell Biology, Dorothy M. Davis Heart and Lung Research Institute, The Ohio State University Wexner Medical Center, Columbus, OH, USA. Electronic address: kedryn.baskin@osumc.edu., Barrientos RM; Institute of Brain, Behavior, and Immunology, The Ohio State University, Columbus, OH, USA; Chronic Brain Injury Program, Discovery Themes Initiative, The Ohio State University, Columbus, OH, USA; Department of Neuroscience, The Ohio State University, Columbus, OH, USA; Department of Psychiatry and Behavioral Health, The Ohio State University, Columbus, OH, USA. Electronic address: ruth.barrientos@osumc.edu.
Source: Brain, behavior, and immunity [Brain Behav Immun] 2026 Feb; Vol. 132, pp. 106220. Date of Electronic Publication: 2025 Dec 09.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 8800478 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1090-2139 (Electronic) Linking ISSN: 08891591 NLM ISO Abbreviation: Brain Behav Immun Subsets: MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22Butler+MJ%22">Butler MJ</searchLink>; Institute of Brain, Behavior, and Immunology, The Ohio State University, Columbus, OH, USA.<br /><searchLink fieldCode="AU" term="%22Blackwell+JA%22">Blackwell JA</searchLink>; Institute of Brain, Behavior, and Immunology, The Ohio State University, Columbus, OH, USA.<br /><searchLink fieldCode="AU" term="%22Sanchez+AA%22">Sanchez AA</searchLink>; Institute of Brain, Behavior, and Immunology, The Ohio State University, Columbus, OH, USA.<br /><searchLink fieldCode="AU" term="%22Sanders+HF%22">Sanders HF</searchLink>; Department of Physiology and Cell Biology, Dorothy M. Davis Heart and Lung Research Institute, The Ohio State University Wexner Medical Center, Columbus, OH, USA.<br /><searchLink fieldCode="AU" term="%22Kolonay+DW%22">Kolonay DW</searchLink>; Department of Physiology and Cell Biology, Dorothy M. Davis Heart and Lung Research Institute, The Ohio State University Wexner Medical Center, Columbus, OH, USA.<br /><searchLink fieldCode="AU" term="%22Jantsch+J%22">Jantsch J</searchLink>; Institute of Brain, Behavior, and Immunology, The Ohio State University, Columbus, OH, USA; Graduate Program in Biosciences, Federal University of Health Sciences of Porto Alegre, Porto Alegre, Rio Grande do Sul, Brazil.<br /><searchLink fieldCode="AU" term="%22Muscat+SM%22">Muscat SM</searchLink>; Institute of Brain, Behavior, and Immunology, The Ohio State University, Columbus, OH, USA.<br /><searchLink fieldCode="AU" term="%22Caetano-Silva+ME%22">Caetano-Silva ME</searchLink>; Department of Health and Kinesiology, University of Illinois Urbana-Champaign, Urbana, IL, USA.<br /><searchLink fieldCode="AU" term="%22Shrestha+A%22">Shrestha A</searchLink>; Department of Health and Kinesiology, University of Illinois Urbana-Champaign, Urbana, IL, USA.<br /><searchLink fieldCode="AU" term="%22Yun+Lim+CK%22">Yun Lim CK</searchLink>; Department of Health and Kinesiology, University of Illinois Urbana-Champaign, Urbana, IL, USA.<br /><searchLink fieldCode="AU" term="%22Mackey-Alfonso+SE%22">Mackey-Alfonso SE</searchLink>; Institute of Brain, Behavior, and Immunology, The Ohio State University, Columbus, OH, USA.<br /><searchLink fieldCode="AU" term="%22Alvarez+BD%22">Alvarez BD</searchLink>; Institute of Brain, Behavior, and Immunology, The Ohio State University, Columbus, OH, USA.<br /><searchLink fieldCode="AU" term="%22McCusker+RH%22">McCusker RH</searchLink>; Department of Health and Kinesiology, University of Illinois Urbana-Champaign, Urbana, IL, USA.<br /><searchLink fieldCode="AU" term="%22Allen+JM%22">Allen JM</searchLink>; Department of Health and Kinesiology, University of Illinois Urbana-Champaign, Urbana, IL, USA.<br /><searchLink fieldCode="AU" term="%22Baskin+KK%22">Baskin KK</searchLink>; Department of Physiology and Cell Biology, Dorothy M. Davis Heart and Lung Research Institute, The Ohio State University Wexner Medical Center, Columbus, OH, USA. Electronic address: kedryn.baskin@osumc.edu.<br /><searchLink fieldCode="AU" term="%22Barrientos+RM%22">Barrientos RM</searchLink>; Institute of Brain, Behavior, and Immunology, The Ohio State University, Columbus, OH, USA; Chronic Brain Injury Program, Discovery Themes Initiative, The Ohio State University, Columbus, OH, USA; Department of Neuroscience, The Ohio State University, Columbus, OH, USA; Department of Psychiatry and Behavioral Health, The Ohio State University, Columbus, OH, USA. Electronic address: ruth.barrientos@osumc.edu.
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