An explainable imaging-clinical biomarker for non-small cell lung cancer prognostication based on normalised hotspot to centroid distance and [18F]FDG PET/CT radiomics.
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| Title: | An explainable imaging-clinical biomarker for non-small cell lung cancer prognostication based on normalised hotspot to centroid distance and [18F]FDG PET/CT radiomics. |
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| Authors: | Chen M; Department of Surgery and Cancer, Imperial College London, Hammersmith Hospital Campus, Du Cane Road, London, W12 0NN, UK. d.mitch.chen@gmail.com.; Department of Radiology & Nuclear Medicine, Imperial College Healthcare NHS Trust, Hammersmith Hospital, Du Cane Road, London, W12 0HS, UK. d.mitch.chen@gmail.com., Copley SJ; Department of Surgery and Cancer, Imperial College London, Hammersmith Hospital Campus, Du Cane Road, London, W12 0NN, UK.; Department of Radiology & Nuclear Medicine, Imperial College Healthcare NHS Trust, Hammersmith Hospital, Du Cane Road, London, W12 0HS, UK., Han Y; Department of Radiology & Nuclear Medicine, Imperial College Healthcare NHS Trust, Hammersmith Hospital, Du Cane Road, London, W12 0HS, UK., Arshad MA; Institute of Nuclear Medicine, University College London, London, NW1 2BU, UK., Viola P; Department of Surgery and Cancer, Imperial College London, Hammersmith Hospital Campus, Du Cane Road, London, W12 0NN, UK.; North West London Pathology, Charing Cross Hospital, London, W6 8RF, UK., Linton-Reid K; Department of Surgery and Cancer, Imperial College London, Hammersmith Hospital Campus, Du Cane Road, London, W12 0NN, UK., Stoycheva T; Department of Radiology & Nuclear Medicine, Imperial College Healthcare NHS Trust, Hammersmith Hospital, Du Cane Road, London, W12 0HS, UK., Cook GJR; Department of Cancer Imaging, School of Biomedical Engineering and Imaging Sciences, King's College London, St. Thomas' Hospital, Westminster Bridge Road, London, SE1 7EH, UK., Landau D; Department of Cancer Imaging, School of Biomedical Engineering and Imaging Sciences, King's College London, St. Thomas' Hospital, Westminster Bridge Road, London, SE1 7EH, UK., Chua S; Department of Nuclear Medicine, The Royal Marsden Hospital, Downs Road, Sutton, SM2 5PT, UK., O'Connor R; Department of Nuclear Medicine, Queen's Medical Centre, Derby Road, Nottingham, NG7 2UH, UK., Dickson J; Department of Clinical Oncology, Mount Vernon Hospital, Rickmansworth Road, Northwood, HA6 2RN, UK., Power D; Department of Clinical Oncology, Imperial College Healthcare NHS Trust, Hammersmith Hospital, Du Cane Road, London, W12 0HS, UK., Rockall AG; Department of Surgery and Cancer, Imperial College London, Hammersmith Hospital Campus, Du Cane Road, London, W12 0NN, UK.; Department of Radiology & Nuclear Medicine, Imperial College Healthcare NHS Trust, Hammersmith Hospital, Du Cane Road, London, W12 0HS, UK., Barwick TD; Department of Surgery and Cancer, Imperial College London, Hammersmith Hospital Campus, Du Cane Road, London, W12 0NN, UK.; Department of Radiology & Nuclear Medicine, Imperial College Healthcare NHS Trust, Hammersmith Hospital, Du Cane Road, London, W12 0HS, UK., Aboagye EO; Department of Surgery and Cancer, Imperial College London, Hammersmith Hospital Campus, Du Cane Road, London, W12 0NN, UK. |
| Source: | European journal of nuclear medicine and molecular imaging [Eur J Nucl Med Mol Imaging] 2026 Apr; Vol. 53 (5), pp. 3195-3212. Date of Electronic Publication: 2025 Dec 12. |
| Publication Type: | Journal Article; Multicenter Study |
| Journal Info: | Publisher: Springer-Verlag Berlin Country of Publication: Germany NLM ID: 101140988 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1619-7089 (Electronic) Linking ISSN: 16197070 NLM ISO Abbreviation: Eur J Nucl Med Mol Imaging Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 41381759 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: An explainable imaging-clinical biomarker for non-small cell lung cancer prognostication based on normalised hotspot to centroid distance and [<superscript>18</superscript>F]FDG PET/CT radiomics. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Chen+M%22">Chen M</searchLink>; Department of Surgery and Cancer, Imperial College London, Hammersmith Hospital Campus, Du Cane Road, London, W12 0NN, UK. d.mitch.chen@gmail.com.; Department of Radiology & Nuclear Medicine, Imperial College Healthcare NHS Trust, Hammersmith Hospital, Du Cane Road, London, W12 0HS, UK. d.mitch.chen@gmail.com.<br /><searchLink fieldCode="AU" term="%22Copley+SJ%22">Copley SJ</searchLink>; Department of Surgery and Cancer, Imperial College London, Hammersmith Hospital Campus, Du Cane Road, London, W12 0NN, UK.; Department of Radiology & Nuclear Medicine, Imperial College Healthcare NHS Trust, Hammersmith Hospital, Du Cane Road, London, W12 0HS, UK.<br /><searchLink fieldCode="AU" term="%22Han+Y%22">Han Y</searchLink>; Department of Radiology & Nuclear Medicine, Imperial College Healthcare NHS Trust, Hammersmith Hospital, Du Cane Road, London, W12 0HS, UK.<br /><searchLink fieldCode="AU" term="%22Arshad+MA%22">Arshad MA</searchLink>; Institute of Nuclear Medicine, University College London, London, NW1 2BU, UK.<br /><searchLink fieldCode="AU" term="%22Viola+P%22">Viola P</searchLink>; Department of Surgery and Cancer, Imperial College London, Hammersmith Hospital Campus, Du Cane Road, London, W12 0NN, UK.; North West London Pathology, Charing Cross Hospital, London, W6 8RF, UK.<br /><searchLink fieldCode="AU" term="%22Linton-Reid+K%22">Linton-Reid K</searchLink>; Department of Surgery and Cancer, Imperial College London, Hammersmith Hospital Campus, Du Cane Road, London, W12 0NN, UK.<br /><searchLink fieldCode="AU" term="%22Stoycheva+T%22">Stoycheva T</searchLink>; Department of Radiology & Nuclear Medicine, Imperial College Healthcare NHS Trust, Hammersmith Hospital, Du Cane Road, London, W12 0HS, UK.<br /><searchLink fieldCode="AU" term="%22Cook+GJR%22">Cook GJR</searchLink>; Department of Cancer Imaging, School of Biomedical Engineering and Imaging Sciences, King's College London, St. Thomas' Hospital, Westminster Bridge Road, London, SE1 7EH, UK.<br /><searchLink fieldCode="AU" term="%22Landau+D%22">Landau D</searchLink>; Department of Cancer Imaging, School of Biomedical Engineering and Imaging Sciences, King's College London, St. Thomas' Hospital, Westminster Bridge Road, London, SE1 7EH, UK.<br /><searchLink fieldCode="AU" term="%22Chua+S%22">Chua S</searchLink>; Department of Nuclear Medicine, The Royal Marsden Hospital, Downs Road, Sutton, SM2 5PT, UK.<br /><searchLink fieldCode="AU" term="%22O'Connor+R%22">O'Connor R</searchLink>; Department of Nuclear Medicine, Queen's Medical Centre, Derby Road, Nottingham, NG7 2UH, UK.<br /><searchLink fieldCode="AU" term="%22Dickson+J%22">Dickson J</searchLink>; Department of Clinical Oncology, Mount Vernon Hospital, Rickmansworth Road, Northwood, HA6 2RN, UK.<br /><searchLink fieldCode="AU" term="%22Power+D%22">Power D</searchLink>; Department of Clinical Oncology, Imperial College Healthcare NHS Trust, Hammersmith Hospital, Du Cane Road, London, W12 0HS, UK.<br /><searchLink fieldCode="AU" term="%22Rockall+AG%22">Rockall AG</searchLink>; Department of Surgery and Cancer, Imperial College London, Hammersmith Hospital Campus, Du Cane Road, London, W12 0NN, UK.; Department of Radiology & Nuclear Medicine, Imperial College Healthcare NHS Trust, Hammersmith Hospital, Du Cane Road, London, W12 0HS, UK.<br /><searchLink fieldCode="AU" term="%22Barwick+TD%22">Barwick TD</searchLink>; Department of Surgery and Cancer, Imperial College London, Hammersmith Hospital Campus, Du Cane Road, London, W12 0NN, UK.; Department of Radiology & Nuclear Medicine, Imperial College Healthcare NHS Trust, Hammersmith Hospital, Du Cane Road, London, W12 0HS, UK.<br /><searchLink fieldCode="AU" term="%22Aboagye+EO%22">Aboagye EO</searchLink>; Department of Surgery and Cancer, Imperial College London, Hammersmith Hospital Campus, Du Cane Road, London, W12 0NN, UK. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22101140988%22">European journal of nuclear medicine and molecular imaging</searchLink> [Eur J Nucl Med Mol Imaging] 2026 Apr; Vol. 53 (5), pp. 3195-3212. <i>Date of Electronic Publication: </i>2025 Dec 12. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article; Multicenter Study – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Springer-Verlag+Berlin%22">Springer-Verlag Berlin </searchLink><i>Country of Publication: </i>Germany <i>NLM ID: </i>101140988 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1619-7089 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2216197070%22">16197070 </searchLink><i>NLM ISO Abbreviation: </i>Eur J Nucl Med Mol Imaging <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=41381759 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1007/s00259-025-07659-4 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 3195 Titles: – TitleFull: An explainable imaging-clinical biomarker for non-small cell lung cancer prognostication based on normalised hotspot to centroid distance and [18F]FDG PET/CT radiomics. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Chen M – PersonEntity: Name: NameFull: Copley SJ – PersonEntity: Name: NameFull: Han Y – PersonEntity: Name: NameFull: Arshad MA – PersonEntity: Name: NameFull: Viola P – PersonEntity: Name: NameFull: Linton-Reid K – PersonEntity: Name: NameFull: Stoycheva T – PersonEntity: Name: NameFull: Cook GJR – PersonEntity: Name: NameFull: Landau D – PersonEntity: Name: NameFull: Chua S – PersonEntity: Name: NameFull: O'Connor R – PersonEntity: Name: NameFull: Dickson J – PersonEntity: Name: NameFull: Power D – PersonEntity: Name: NameFull: Rockall AG – PersonEntity: Name: NameFull: Barwick TD – PersonEntity: Name: NameFull: Aboagye EO IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 04 Text: 2026 Apr Type: published Y: 2026 Identifiers: – Type: issn-electronic Value: 1619-7089 Numbering: – Type: volume Value: 53 – Type: issue Value: 5 Titles: – TitleFull: European journal of nuclear medicine and molecular imaging Type: main |
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