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FDG-PET-Based Selective Deescalation of Chemoradiation in Human Papillomavirus-Related Oropharyngeal Squamous Cell Carcinoma: A Multicenter Phase II Trial.

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Title: FDG-PET-Based Selective Deescalation of Chemoradiation in Human Papillomavirus-Related Oropharyngeal Squamous Cell Carcinoma: A Multicenter Phase II Trial.
Authors: Mierzwa M; Department of Radiation Oncology, University of Michigan, Ann Arbor, Michigan., Rosen B; Department of Radiation Oncology, University of Michigan, Ann Arbor, Michigan., Suresh K; Department of Radiation Oncology, University of Michigan, Ann Arbor, Michigan.; Department of Biostatistics, University of Michigan, Ann Arbor, Michigan., Dinesh A; Department of Otolaryngology - Head & Neck Surgery, University of Michigan, Ann Arbor, Michigan., Regan S; Department of Radiation Oncology, University of Michigan, Ann Arbor, Michigan., Brummel C; Department of Otolaryngology - Head & Neck Surgery, University of Michigan, Ann Arbor, Michigan., Wong K; Division of Nuclear Medicine, Department of Radiology, University of Michigan, Ann Arbor, Michigan., Casper K; Department of Otolaryngology - Head & Neck Surgery, University of Michigan, Ann Arbor, Michigan., Prince M; Department of Otolaryngology - Head & Neck Surgery, University of Michigan, Ann Arbor, Michigan., Malloy K; Department of Otolaryngology - Head & Neck Surgery, University of Michigan, Ann Arbor, Michigan., Shuman A; Department of Otolaryngology - Head & Neck Surgery, University of Michigan, Ann Arbor, Michigan., Chinn S; Department of Otolaryngology - Head & Neck Surgery, University of Michigan, Ann Arbor, Michigan., Cao Y; Department of Radiation Oncology, University of Michigan, Ann Arbor, Michigan., Aryal M; Department of Radiation Oncology, University of Michigan, Ann Arbor, Michigan., Heft-Neal M; Department of Otolaryngology - Head & Neck Surgery, University of Michigan, Ann Arbor, Michigan., Stucken C; Department of Otolaryngology - Head & Neck Surgery, University of Michigan, Ann Arbor, Michigan., Buchakjian M; Department of Otolaryngology - Head & Neck Surgery, University of Michigan, Ann Arbor, Michigan., Forner D; Department of Otolaryngology - Head & Neck Surgery, University of Michigan, Ann Arbor, Michigan., Yalamanchi P; Department of Otolaryngology - Head & Neck Surgery, University of Michigan, Ann Arbor, Michigan., Swiecicki P; Division of Hematology Oncology, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan., Lawrence TS; Department of Radiation Oncology, University of Michigan, Ann Arbor, Michigan., Akhdar R; Department of Otolaryngology - Head & Neck Surgery, University of Michigan, Ann Arbor, Michigan., Tewari M; Division of Hematology Oncology, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan., Bhambhani C; Division of Hematology Oncology, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan., Walline H; Department of Otolaryngology - Head & Neck Surgery, University of Michigan, Ann Arbor, Michigan., Brenner JC; Department of Otolaryngology - Head & Neck Surgery, University of Michigan, Ann Arbor, Michigan., Shah J; Department of Radiation Oncology, University of Michigan, Ann Arbor, Michigan., Worden F; Division of Hematology Oncology, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan.
Source: Clinical cancer research : an official journal of the American Association for Cancer Research [Clin Cancer Res] 2026 Feb 17; Vol. 32 (4), pp. 684-693.
Publication Type: Journal Article; Clinical Trial, Phase II; Multicenter Study
Journal Info: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 9502500 Publication Model: Print Cited Medium: Internet ISSN: 1557-3265 (Electronic) Linking ISSN: 10780432 NLM ISO Abbreviation: Clin Cancer Res Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Mierzwa+M%22">Mierzwa M</searchLink>; Department of Radiation Oncology, University of Michigan, Ann Arbor, Michigan.<br /><searchLink fieldCode="AU" term="%22Rosen+B%22">Rosen B</searchLink>; Department of Radiation Oncology, University of Michigan, Ann Arbor, Michigan.<br /><searchLink fieldCode="AU" term="%22Suresh+K%22">Suresh K</searchLink>; Department of Radiation Oncology, University of Michigan, Ann Arbor, Michigan.; Department of Biostatistics, University of Michigan, Ann Arbor, Michigan.<br /><searchLink fieldCode="AU" term="%22Dinesh+A%22">Dinesh A</searchLink>; Department of Otolaryngology - Head & Neck Surgery, University of Michigan, Ann Arbor, Michigan.<br /><searchLink fieldCode="AU" term="%22Regan+S%22">Regan S</searchLink>; Department of Radiation Oncology, University of Michigan, Ann Arbor, Michigan.<br /><searchLink fieldCode="AU" term="%22Brummel+C%22">Brummel C</searchLink>; Department of Otolaryngology - Head & Neck Surgery, University of Michigan, Ann Arbor, Michigan.<br /><searchLink fieldCode="AU" term="%22Wong+K%22">Wong K</searchLink>; Division of Nuclear Medicine, Department of Radiology, University of Michigan, Ann Arbor, Michigan.<br /><searchLink fieldCode="AU" term="%22Casper+K%22">Casper K</searchLink>; Department of Otolaryngology - Head & Neck Surgery, University of Michigan, Ann Arbor, Michigan.<br /><searchLink fieldCode="AU" term="%22Prince+M%22">Prince M</searchLink>; Department of Otolaryngology - Head & Neck Surgery, University of Michigan, Ann Arbor, Michigan.<br /><searchLink fieldCode="AU" term="%22Malloy+K%22">Malloy K</searchLink>; Department of Otolaryngology - Head & Neck Surgery, University of Michigan, Ann Arbor, Michigan.<br /><searchLink fieldCode="AU" term="%22Shuman+A%22">Shuman A</searchLink>; Department of Otolaryngology - Head & Neck Surgery, University of Michigan, Ann Arbor, Michigan.<br /><searchLink fieldCode="AU" term="%22Chinn+S%22">Chinn S</searchLink>; Department of Otolaryngology - Head & Neck Surgery, University of Michigan, Ann Arbor, Michigan.<br /><searchLink fieldCode="AU" term="%22Cao+Y%22">Cao Y</searchLink>; Department of Radiation Oncology, University of Michigan, Ann Arbor, Michigan.<br /><searchLink fieldCode="AU" term="%22Aryal+M%22">Aryal M</searchLink>; Department of Radiation Oncology, University of Michigan, Ann Arbor, Michigan.<br /><searchLink fieldCode="AU" term="%22Heft-Neal+M%22">Heft-Neal M</searchLink>; Department of Otolaryngology - Head & Neck Surgery, University of Michigan, Ann Arbor, Michigan.<br /><searchLink fieldCode="AU" term="%22Stucken+C%22">Stucken C</searchLink>; Department of Otolaryngology - Head & Neck Surgery, University of Michigan, Ann Arbor, Michigan.<br /><searchLink fieldCode="AU" term="%22Buchakjian+M%22">Buchakjian M</searchLink>; Department of Otolaryngology - Head & Neck Surgery, University of Michigan, Ann Arbor, Michigan.<br /><searchLink fieldCode="AU" term="%22Forner+D%22">Forner D</searchLink>; Department of Otolaryngology - Head & Neck Surgery, University of Michigan, Ann Arbor, Michigan.<br /><searchLink fieldCode="AU" term="%22Yalamanchi+P%22">Yalamanchi P</searchLink>; Department of Otolaryngology - Head & Neck Surgery, University of Michigan, Ann Arbor, Michigan.<br /><searchLink fieldCode="AU" term="%22Swiecicki+P%22">Swiecicki P</searchLink>; Division of Hematology Oncology, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan.<br /><searchLink fieldCode="AU" term="%22Lawrence+TS%22">Lawrence TS</searchLink>; Department of Radiation Oncology, University of Michigan, Ann Arbor, Michigan.<br /><searchLink fieldCode="AU" term="%22Akhdar+R%22">Akhdar R</searchLink>; Department of Otolaryngology - Head & Neck Surgery, University of Michigan, Ann Arbor, Michigan.<br /><searchLink fieldCode="AU" term="%22Tewari+M%22">Tewari M</searchLink>; Division of Hematology Oncology, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan.<br /><searchLink fieldCode="AU" term="%22Bhambhani+C%22">Bhambhani C</searchLink>; Division of Hematology Oncology, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan.<br /><searchLink fieldCode="AU" term="%22Walline+H%22">Walline H</searchLink>; Department of Otolaryngology - Head & Neck Surgery, University of Michigan, Ann Arbor, Michigan.<br /><searchLink fieldCode="AU" term="%22Brenner+JC%22">Brenner JC</searchLink>; Department of Otolaryngology - Head & Neck Surgery, University of Michigan, Ann Arbor, Michigan.<br /><searchLink fieldCode="AU" term="%22Shah+J%22">Shah J</searchLink>; Department of Radiation Oncology, University of Michigan, Ann Arbor, Michigan.<br /><searchLink fieldCode="AU" term="%22Worden+F%22">Worden F</searchLink>; Division of Hematology Oncology, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan.
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