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IL-36γ armored CAR T cells reprogram neutrophils to induce endogenous antitumor immunity.

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Title: IL-36γ armored CAR T cells reprogram neutrophils to induce endogenous antitumor immunity.
Authors: Zuo Y; Department of Medicine, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14263, USA., Vohwinkel DJ; Department of Medicine, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14263, USA., Dong B; Department of Immunology, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14263, USA., McDowell JR; Department of Medicine, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14263, USA., Guzman BV; Department of Medicine, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14263, USA., Manickavel Pandian TS; Department of Immunology, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14263, USA., Chattopadhyay S; Department of Immunology, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14263, USA., McGray AJR; Department of Immunology, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14263, USA., Olejniczak SH; Department of Immunology, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14263, USA., Ohm J; Department of Cancer Genetics & Genomics, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14263, USA., Wang J; Department of Biostatistics and Bioinformatics, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14263, USA., Long MD; Department of Biostatistics and Bioinformatics, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14263, USA., Gomez EC; Department of Biostatistics and Bioinformatics, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14263, USA., Purdon TJ; Department of Medicine, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14263, USA., Luo W; Flow and Image Cytometry Shared Resource, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14263, USA., Mohammadpour H; Department of Cell Stress Biology, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14263, USA., Hackett CS; Department of Medicine, Weill Cornell Medicine, New York, NY 10065, USA., Cherkassky L; Department of Immunology, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14263, USA; Department of Surgical Oncology, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14203, USA., Davila M; Department of Medicine, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14263, USA., Abrams SI; Department of Immunology, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14263, USA. Electronic address: Scott.Abrams@RoswellPark.org., Brentjens RJ; Department of Medicine, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14263, USA. Electronic address: renier.brentjens@roswellpark.org.
Source: Cancer cell [Cancer Cell] 2026 Feb 09; Vol. 44 (2), pp. 366-382.e10. Date of Electronic Publication: 2025 Dec 11.
Publication Type: Journal Article
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101130617 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-3686 (Electronic) Linking ISSN: 15356108 NLM ISO Abbreviation: Cancer Cell Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: IL-36γ armored CAR T cells reprogram neutrophils to induce endogenous antitumor immunity.
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  Data: <searchLink fieldCode="AU" term="%22Zuo+Y%22">Zuo Y</searchLink>; Department of Medicine, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14263, USA.<br /><searchLink fieldCode="AU" term="%22Vohwinkel+DJ%22">Vohwinkel DJ</searchLink>; Department of Medicine, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14263, USA.<br /><searchLink fieldCode="AU" term="%22Dong+B%22">Dong B</searchLink>; Department of Immunology, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14263, USA.<br /><searchLink fieldCode="AU" term="%22McDowell+JR%22">McDowell JR</searchLink>; Department of Medicine, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14263, USA.<br /><searchLink fieldCode="AU" term="%22Guzman+BV%22">Guzman BV</searchLink>; Department of Medicine, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14263, USA.<br /><searchLink fieldCode="AU" term="%22Manickavel+Pandian+TS%22">Manickavel Pandian TS</searchLink>; Department of Immunology, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14263, USA.<br /><searchLink fieldCode="AU" term="%22Chattopadhyay+S%22">Chattopadhyay S</searchLink>; Department of Immunology, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14263, USA.<br /><searchLink fieldCode="AU" term="%22McGray+AJR%22">McGray AJR</searchLink>; Department of Immunology, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14263, USA.<br /><searchLink fieldCode="AU" term="%22Olejniczak+SH%22">Olejniczak SH</searchLink>; Department of Immunology, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14263, USA.<br /><searchLink fieldCode="AU" term="%22Ohm+J%22">Ohm J</searchLink>; Department of Cancer Genetics & Genomics, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14263, USA.<br /><searchLink fieldCode="AU" term="%22Wang+J%22">Wang J</searchLink>; Department of Biostatistics and Bioinformatics, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14263, USA.<br /><searchLink fieldCode="AU" term="%22Long+MD%22">Long MD</searchLink>; Department of Biostatistics and Bioinformatics, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14263, USA.<br /><searchLink fieldCode="AU" term="%22Gomez+EC%22">Gomez EC</searchLink>; Department of Biostatistics and Bioinformatics, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14263, USA.<br /><searchLink fieldCode="AU" term="%22Purdon+TJ%22">Purdon TJ</searchLink>; Department of Medicine, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14263, USA.<br /><searchLink fieldCode="AU" term="%22Luo+W%22">Luo W</searchLink>; Flow and Image Cytometry Shared Resource, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14263, USA.<br /><searchLink fieldCode="AU" term="%22Mohammadpour+H%22">Mohammadpour H</searchLink>; Department of Cell Stress Biology, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14263, USA.<br /><searchLink fieldCode="AU" term="%22Hackett+CS%22">Hackett CS</searchLink>; Department of Medicine, Weill Cornell Medicine, New York, NY 10065, USA.<br /><searchLink fieldCode="AU" term="%22Cherkassky+L%22">Cherkassky L</searchLink>; Department of Immunology, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14263, USA; Department of Surgical Oncology, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14203, USA.<br /><searchLink fieldCode="AU" term="%22Davila+M%22">Davila M</searchLink>; Department of Medicine, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14263, USA.<br /><searchLink fieldCode="AU" term="%22Abrams+SI%22">Abrams SI</searchLink>; Department of Immunology, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14263, USA. Electronic address: Scott.Abrams@RoswellPark.org.<br /><searchLink fieldCode="AU" term="%22Brentjens+RJ%22">Brentjens RJ</searchLink>; Department of Medicine, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14263, USA. Electronic address: renier.brentjens@roswellpark.org.
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  Data: <searchLink fieldCode="JN" term="%22101130617%22">Cancer cell</searchLink> [Cancer Cell] 2026 Feb 09; Vol. 44 (2), pp. 366-382.e10. <i>Date of Electronic Publication: </i>2025 Dec 11.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Cell+Press%22">Cell Press </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101130617 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1878-3686 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2215356108%22">15356108 </searchLink><i>NLM ISO Abbreviation: </i>Cancer Cell <i>Subsets: </i>MEDLINE
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